ped-1. Evaluation of Celiac Disease Serologic Markers in Pediatric Patients with Type 1 Diabetes Mellitus

2003 ◽  
Vol 96 (Supplement) ◽  
pp. S70-S71
Author(s):  
Dina S. Parekh ◽  
Cydney Fenton ◽  
David Bush
2015 ◽  
Vol 18 (7) ◽  
pp. A603
Author(s):  
J López-Bastida ◽  
J Oliva Moreno ◽  
JP López-Siguero ◽  
LA Vázquez ◽  
D Jiang ◽  
...  

Author(s):  
Basma Haris ◽  
Ahmed Abdellatief ◽  
Houda Afyouni ◽  
Tasneem Abdel-Karim ◽  
Shayma Mohammed ◽  
...  

Abstract Objectives Children with antibody positive type 1 diabetes mellitus (type 1 diabetes) are at an increased risk of developing celiac disease (CD) which suggests a common autoimmune basis with both high-risk human lymphocyte antigen (HLA) and non-HLA factors playing a role in the pathophysiology. We aim to describe the prevalence, immune profile, and clinical characteristics of children with CD who have type 1 diabetes mellitus in Qatar. Methods All children (aged 0–18 years) attending a regional diabetes clinic with antibody positive type 1 diabetes were screened for CD. Measurement of tissue transglutaminase IgA and IgG as well as anti-endomysial antibody, was done, clinical details about the birth history, family history of diabetes and CD, age of onset, and ethnicity were collected. Results Out of the 1,325 children with antibody positive type 1 diabetes, 54 were identified to have CD on screening and then confirmed on small bowel biopsy. The prevalence of CD in the type 1 diabetes childhood population in Qatar is 4.07%. CD and type 1 diabetes were more prevalent in the Qatari children (n=32) as compared to non-Qatari (n=22) and occurred mostly in the age group 6–10 years. The most common type 1 diabetes antibodies in children with CD were glutamic acid decarboxylase and insulin autoantibody. Twelve subjects were asymptomatic for CD symptoms and picked up only on screening. Conclusions The prevalence of CD in children with type 1 diabetes in Qatar is comparable to reports from around the world. Many children were asymptomatic and thus routine screening is recommended.


2011 ◽  
pp. P3-746-P3-746
Author(s):  
Monica Grover ◽  
Andrea Erika Balazs ◽  
Carlos A Bacino ◽  
Christian Patrick Schaaf ◽  
Saul J Karpen ◽  
...  

2018 ◽  
Vol 19 (4) ◽  
pp. 749-755 ◽  
Author(s):  
Itay Tokatly Latzer ◽  
Marianna Rachmiel ◽  
Nehama Zuckerman Levin ◽  
Kineret Mazor-Aronovitch ◽  
Zohar Landau ◽  
...  

2021 ◽  
Author(s):  
Jyoti Diwakar ◽  
Arghadip Samaddar ◽  
Subhas Kanti Konar ◽  
Maya Dattatraya Bhat ◽  
Emma Manuel ◽  
...  

2021 ◽  
Vol 27 (12) ◽  
pp. S38
Author(s):  
Paras Imran ◽  
Saeeda Fouzia Qasim ◽  
Saba Latif ◽  
Mohammad Yahya ◽  
Saima Athar Shaikh

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