High-Performance Liquid Chromatographic Method with Diode Array Detection for Identification and Quantification of the Eight New Antidepressants and Five of Their Active Metabolites in Plasma after Overdose

2003 ◽  
Vol 25 (5) ◽  
pp. 581-587 ◽  
Author(s):  
Karine Titier ◽  
Nadège Castaing ◽  
Emmanuelle Scotto-Gomez ◽  
Fabienne Pehourcq ◽  
Nicholas Moore ◽  
...  
Keyword(s):  
High Performance ◽  
Chromatographic Method ◽  
High Performance Liquid Chromatographic ◽  
Diode Array ◽  
Diode Array Detection ◽  
Active Metabolites ◽  
Liquid Chromatographic Method ◽  
Array Detection ◽  
Liquid Chromatographic ◽  
Identification And Quantification

Fingerprint Analysis of Polygonatum odoratum (Mill.) Druce Using High-Performance Liquid Chromatographic Method with Diode-Array Detection

2013 ◽  
Vol 781-784 ◽  
pp. 1199-1202
Author(s):  
Guang Sheng Xi
Keyword(s):  
High Performance ◽  
High Performance Liquid Chromatographic ◽  
Diode Array ◽  
Diode Array Detection ◽  
Fingerprint Analysis ◽  
Line Identification ◽  
Liquid Chromatographic Method ◽  
Average Similarity ◽  
Array Detection ◽  
Liquid Chromatographic

The fingerprints analysis of different lines ofPolygonatum odoratum(Mill.) Druce were established by high-performance liquid chromatographic with diode-array detection (HPLC/DAD). The analyses were performed on ZORBAX Eclipse XDB-C18(4.6×250 mm, 5 μm) column using a mobile phase (aqueous 0.05% formic acid-acetonitrile) under gradient conditions. The flow rate was 1.0 ml/min. The detecting wavelength was set at 210 nm. HPLC fingerprints of two lines were little different. The similarity of the same line was greater than 0.9, and the average similarity of the different lines was 0.794. This method could be suitable for the line identification and quality control ofPolygonatum odoratum(Mill.) Druce.

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