scholarly journals 828: OUTCOMES IN ACUTE STROKE THROMBECTOMY PATIENTS: GENERAL ANESTHESIA VERSUS CONSCIOUS SEDATION

2021 ◽  
Vol 50 (1) ◽  
pp. 408-408
Author(s):  
Daniel Najafali ◽  
Adelina Buganu ◽  
Kim Vuong ◽  
Bhakti Panchal ◽  
Muhammad Ullah ◽  
...  
2021 ◽  
Vol 7 (3) ◽  
pp. 201
Author(s):  
PengRoc Chen ◽  
MehmetEnes Inam ◽  
Elvira Lekka ◽  
FaheemG Sheriff ◽  
AdityaA Sanzgiri ◽  
...  

2016 ◽  
Vol 39 (9) ◽  
pp. 1239-1244 ◽  
Author(s):  
H. Janssen ◽  
G. Buchholz ◽  
M. Killer ◽  
L. Ertl ◽  
H. Brückmann ◽  
...  

2021 ◽  
Vol 26 (2) ◽  
pp. 47-51
Author(s):  
Levi W. Howard ◽  
Bart M. Demaerschalk ◽  
Brian W. Chong ◽  
Bernard R. Bendok ◽  
David Gritsch ◽  
...  

2015 ◽  
Vol 8 (9) ◽  
pp. 883-888 ◽  
Author(s):  
Manoj Jagani ◽  
Waleed Brinjikji ◽  
Alejandro A Rabinstein ◽  
Jeffrey J Pasternak ◽  
David F Kallmes

Background and purposeMany studies have suggested a relationship between the type of anesthesia provided during intra-arterial therapy for acute ischemic stroke and patient outcomes. Variability in blood pressure and hypotension have previously been identified as possible reasons for worse outcomes in acute stroke. Our aim was to investigate hemodynamic parameters and neurological outcomes of patients receiving either general anesthesia or conscious sedation for intra-arterial therapy of acute stroke.MethodsWe performed a retrospective review of patients undergoing intra-arterial therapy from December 2008 to March 2015. Demographic data, baseline National Institutes of Health Stroke Scale score, preoperative physiological variables, procedural details, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate, and modified Rankin Scale scores were recorded.Results99 patients were included in the study, with 38 receiving general anesthesia and 61 receiving conscious sedation. Patients who received general anesthesia had a lower maximum SBP (p=0.02), minimum SBP (p<0.0001), minimum DBP (p<0.0001), and minimum MAP (p<0.0001). On multivariate analysis, general anesthesia was associated with lower minimum SBP (p=0.04), DBP (p=0.02), and MAP (p=0.007). Conscious sedation was associated with more favorable neurological outcomes (p=0.02). Patients with favorable neurological outcomes had a lower maximum variability in SBP (p=0.01) and MAP (p=0.03), as well as a higher minimum DBP (p=0.03).ConclusionsPatients with acute ischemic stroke undergoing intra-arterial therapy with general anesthesia had lower minimum SBP, DBP, and MAP, greater fluctuations in blood pressure, and less favorable outcomes. More studies are needed to examine the implications of variable and reduced blood pressures and neurological outcomes.


2018 ◽  
Vol 69 (1) ◽  
pp. 24-29 ◽  
Author(s):  
Hae Jin Kim ◽  
Byung Kwan Park ◽  
In Sun Chung

Purpose Percutaneous radiofrequency ablation is so painful that this treatment requires pain control such as conscious sedation or general anesthesia. It is still unclear which type of anesthesia is better for treatment outcomes of renal cell carcinoma. This study aimed to compare general anesthesia and conscious sedation in treating patients with renal cell carcinoma with radiofrequency ablation. Methods Between 2010 and 2015, 51 patients with biopsy-proven renal cell carcinomas (<4 cm) were treated with computed tomography–guided radiofrequency ablation. General anesthesia was performed in 41 and conscious sedation was performed in 10 patients. Tumour size, local tumour progression, metastasis, major complication, effective dose, glomerular filtration rate difference, and recurrence-free survival rate were compared between these groups. Results The mean tumour size was 2.1 cm in both groups ( P = .673). Local tumour progression occurred in 0% (0 of 41) of the general anesthesia group, but in 40% (4 of 10) of the conscious sedation group ( P = .001). Metastases in these groups occurred in 2.4% (1 of 41) of the general anesthesia group and 20% (2 of 10) of the conscious sedation group ( P = .094). No major complications developed in either group after the first radiofrequency ablation session. The mean effective doses in these groups were 21.7 mSv and 21.2 mSv, respectively ( P = .868). The mean glomerular filtration rate differences in the general anesthesia and conscious sedation groups were −13.5 mL/min/1.73 m2 and −19.1 mL/min/1.73 m2, respectively ( P = .575). Three-year recurrence-free survival rates in these groups were 97.6% and 60.0%, respectively ( P = .001). Conclusions General anesthesia may provide better intermediate outcomes than conscious sedation in treating small renal cell carcinomas with radiofrequency ablation.


Neurosurgery ◽  
2016 ◽  
Vol 63 ◽  
pp. 155 ◽  
Author(s):  
François Alesch ◽  
Roshini Jain ◽  
Lilly Chen ◽  
Thomas Brucke ◽  
Fernando Seijo ◽  
...  

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