Celiac Disease with Mild to Moderate Histologic Changes is a Common Cause of Chronic Diarrhea in Indian Children

2005 ◽  
Vol 41 (2) ◽  
pp. 204-209 ◽  
Author(s):  
Shinjini Bhatnagar ◽  
Sidhartha Datta Gupta ◽  
Meera Mathur ◽  
Alan D Phillips ◽  
Ramesh Kumar ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Chronic Diarrhea ◽  
Indian Children ◽  
Common Cause ◽  
Histologic Changes

scholarly journals The clinical spectrum of chronic diarrhoea in children in a tertiary care hospital in Bangalore, India

2018 ◽  
Vol 5 (4) ◽  
pp. 1267 ◽  
Author(s):  
Bhaskar Shenoy ◽  
Sunil Kumar Dodderi
Keyword(s):  
Celiac Disease ◽  
Milk Protein ◽  
Chronic Diarrhea ◽  
Tertiary Care ◽  
Cow Milk ◽  
Chronic Diarrhoea ◽  
Care Hospital ◽  
Common Cause ◽  
Protein Intolerance ◽  
Post Infectious

Background: In the developing world, chronic diarrhea is typically associated with serial enteric infections and malnutrition. There are many causes for chronic diarrhea and with better facilities these are being increasingly diagnosed in India. To study the clinical spectrum of chronic diarrhoea in children. in a tertiary care hospital in BangaloreMethods: This was a prospective observational study conducted at the Dept of Pediatrics, Dr.B.R.Ambedkar Medical College , Bangalore from April 2015 to April 2017. All the patients who presented with symptoms suggestive of chronic diarrhoea were enrolled for the study. 50 children fulfilling inclusion criteria were selected for the study.Results: Of 50 cases, 31(62%) showed cow milk protein intolerance (CMPI), 6 (12%) celiac disease, 5(10%) post infectious, 2(4%) glucose galactose intolerance, 1(2%) non-specific, 1(2%) cystic fibrosis, 1(2%) IBD, TB 1(2%) and 2(4%) lympangiectesia. In children below 2 years, cow milk protein intolerance was the most common cause of diarrhea whereas post infectious was the most common cause in 2-6 years age group and celiac disease in above 6 years of age group.Conclusions: Cow milk protein intolerance is the most common etiological factor. The incidence of celiac disease was the second most common cause after CMPI in the present study. The incidence of CMPI as a cause of chronic diarrhoea reduces as the age increases as seen in present study. The high incidence of celiac diseases may be due to referral to our institution by various peripheral hospitals when they could not diagnose after routine investigations.

Lymphocytic Gastritis and Celiac Disease in Indian Children: Evidence of a Positive Relation

2008 ◽  
Vol 47 (5) ◽  
pp. 568-572 ◽  
Author(s):  
Kaushal K Prasad ◽  
Babu R Thapa ◽  
Sadhna Lal ◽  
Arun K Sharma ◽  
Chander K Nain ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Positive Relation ◽  
Indian Children ◽  
Lymphocytic Gastritis

scholarly journals Association between Endoscopic Findings Vs. Serology Findings of Patients with Suspected Celiac Disease

2021 ◽  
pp. 301-307
Author(s):  
Anwar Hussain Abbasi ◽  
Khawaja Ishfaq Ahmed ◽  
Nadeem Yousuf ◽  
Mahjabeen Fatima Qureshi ◽  
Muhammad Shahzeb Shaikh ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Chronic Diarrhea ◽  
Villous Atrophy ◽  
Clinical Manifestations ◽  
Final Analysis ◽  
Normal Mucosa ◽  
Diagnostic Value ◽  
Endoscopic Evaluation ◽  
Drug Induced ◽  
Endoscopic Findings

Objective: To determine the association between endoscopic findings vs. serology findings of patients with suspected celiac disease Methods: All the suspected cases (based on their clinical manifestations) of celiac disease were initially recruited having age >14 years and <40 years of both gender. Patients who did not willing to participate, patients already taking gluten diet for more than 3 months, patients with other causes of chronic diarrhea and alternate diagnosis like thyrotoxicosis, whipple’s disease, giardiasis, patients with drug induced diarrhea, patients in whom we cannot perform endoscopy, pregnant women, and patients already diagnosed cases of celiac disease were excluded from this study. Celiac disease was confirmed based on positive anti-tTG antibodies. Endoscopic evaluation of duodenum was performed in all positive cases. Results: A total of 50 patients were recruited for final analysis. Diagnostic accuracy of endoscopy was 34.6%. Young population (31.14±6.07 years) with females predominance (72%, n=36) were more common than males. The most common symptoms were presence of chronic diarrhea (74%, n=37) followed by abdominal pain (52%, n=26), nausea & vomiting (34%, n=17), and least common was presence of constipation (2%, n=1). On endoscopic evaluation, out of 50 positive anti-tTG antibodies cases, 24 had normal mucosa while partial villous atrophy observed in 15 (30%) cases and total villous atrophy observed in 11 cases (22%). Conclusions: Celiac disease was more prevalent in young females and patients usually presents with history of chronic diarrhea. Anti-tTG antibodies have more diagnostic value than duodenal endoscopy. Villous atrophy was found in more than 50% of the patients who were diagnosed with celiac disease.

A Single Institution’s Experience of Primary Headache in Children With Celiac Disease

2019 ◽  
Vol 35 (1) ◽  
pp. 37-41 ◽  
Author(s):  
Grant L. Hom ◽  
Brian L. Hom ◽  
Barbara Kaplan ◽  
A. David Rothner
Keyword(s):  
Celiac Disease ◽  
Tissue Transglutaminase ◽  
Primary Headache ◽  
Tension Type Headache ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Phone Survey ◽  
Type Headache ◽  
The Impact ◽  
Histologic Changes

Background: Few studies exist examining the frequency of primary headache in children with celiac disease and the impact of a gluten-free diet on primary headache symptomology. This study explores characteristics and frequency of headaches in children with celiac disease and response to gluten-free diet at a single institution. Methods: Medical records were reviewed for children with celiac disease confirmed by the presence of elevated tissue transglutaminase IgA levels and histologic changes consistent with the diagnosis of celiac disease on small bowel biopsy. Eligible participants were contacted via letter for participation in a phone survey regarding headaches. Phone interviews were conducted 2 weeks after notification and lasted approximately 10 minutes. Headaches were classified according to ICHD-3 criteria. Results: 247 eligible patients or their families were contacted. A total of 132 (53.44%) agreed to participate. One participant was excluded due to insufficient information provided. Overall, 51 of 131 participants had recurrent headache defined as at least 1 episode per month (39%, 95% confidence interval [CI]: 31%-47%) and 33 had migraine with or without aura (25%, 95% CI: 18%-33%). Twenty-eight had frequent tension-type headache (22%, 95% CI: 15%-29%). Thirty-two participants noted headaches before a confirmed diagnosis of celiac disease. Twenty-two of 32 participants (68.75%) noticed decreased headache frequency or intensity, or both, after starting the gluten-free diet. Conclusion: This study suggests that at least one-third of children and adolescents with celiac disease have recurrent headaches at the time of diagnosis. A gluten-free diet led to improved headache symptomology in a significant number of these patients.

Cystic fibrosis and celiac disease - multifaceted and similar

Folia Medica ◽  
2013 ◽  
Vol 55 (3-4) ◽  
pp. 87-89 ◽  
Author(s):  
Nelly D. Genkova ◽  
Ivan V. Yankov ◽  
Miroslava N. Bosheva ◽  
Benjamin L. Anavi ◽  
Dafina G. Grozeva ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Celiac Disease ◽  
Chronic Diarrhea ◽  
Serological Test ◽  
Clinical Manifestations ◽  
Duodenal Mucosa ◽  
Gluten Free ◽  
Immunological Tests ◽  
Targeted Screening ◽  
Sweat Tests

ABSTRACT Celiac disease and cystic fibrosis share a number of clinical manifestations. The comorbidity rate of these diseases is low: 1:200000. We present a case of a child aged 1 year and 5 months, born to a mixed-marriage parents, with concomitant cystic fibrosis and celiac disease manifesting initially with chronic diarrhea. Diagnosis of cystic fibrosis was made on the basis of changes in pulmonogram and three positive sweat tests with the malabsorption managed. Celiac disease was demonstrated through immunological tests (serological test of anti-transglutaminase antibodies of IgA class), histological tests (altered duodenal mucosa) and the therapeutic effect of a gluten-free diet. This case is the first ever reported case of a child with concomitant cystic fibrosis and celiac disease in Bulgaria. The case suggests the need for targeted screening for celiac disease in children with cystic fibrosis.

scholarly journals Severe persistent unremitting dermatitis, chronic diarrhea and hypoalbuminemia in a child; Hartnup disease in setting of celiac disease

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Thomas Ciecierega ◽  
Imad Dweikat ◽  
Mohammad Awar ◽  
Maher Shahrour ◽  
Bassam Abu Libdeh ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Chronic Diarrhea

Assessment of dietary compliance to Gluten Free Diet and psychosocial problems in Indian children with celiac disease

2010 ◽  
Vol 77 (6) ◽  
pp. 649-654 ◽  
Author(s):  
J. C. Chauhan ◽  
Praveen Kumar ◽  
A. K. Dutta ◽  
Srikanta Basu ◽  
Arun Kumar
Keyword(s):  
Celiac Disease ◽  
Psychosocial Problems ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Indian Children ◽  
Dietary Compliance

scholarly journals Tetany caused by chronic diarrhea in a child with celiac disease: A case report

Cases Journal ◽  
2008 ◽  
Vol 1 (1) ◽  
pp. 176 ◽  
Author(s):  
Jaime Hurtado-Valenzuela ◽  
Norberto Sotelo-Cruz ◽  
Guillermo López-Cervantes ◽  
Ana María de la Barca
Keyword(s):  
Celiac Disease ◽  
Case Report ◽  
Chronic Diarrhea
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