The Utility of Deep Soft-Tissue Cultures in Diagnosing the Causative Agent of Sternal Osteomyelitis following Median Sternotomy

2007 ◽  
Vol 119 (2) ◽  
pp. 568-572 ◽  
Author(s):  
Alexander M. Spiess ◽  
Tanju Istanbullu ◽  
Patricia D. Brown ◽  
Chenicheri Balakrishnan ◽  
Eti Gursel
2008 ◽  
Vol 98 (4) ◽  
pp. 290-295 ◽  
Author(s):  
M. Bulent Ertugrul ◽  
Selcuk Baktiroglu ◽  
Serpil Salman ◽  
Seher Unal ◽  
Murat Aksoy ◽  
...  

Background: We sought to determine the similarity of pathogens isolated from soft tissue and bone in patients with diabetic foot infections. It is widely believed that soft-tissue cultures are adequate in the determination of causative bacteria in patients with diabetic foot osteomyelitis. The culture results of specimens taken concurrently from soft-tissue and bone infections show that the former does not predict the latter with sufficient reliability. We sought to determine the similarity of pathogens isolated from soft tissue and bone in patients with diabetic foot infections. Methods: Forty-five patients with diabetic foot infections were enrolled in the study. Patients had to have clinically suspected foot lesions of grade 3 or higher on the Wagner classification system. In patients with clinically suspected osteomyelitis, magnetic resonance imaging, scintigraphy, or histopathologic examination were performed. Bone and deep soft tissue specimens were obtained from all patients by open surgical procedures under aseptic conditions during debridement or amputation. The specimens were compared only with the other specimens taken from the same patients. Results: The results of bone and soft-tissue cultures were identical in 49% (n = 22) of cases. In 11% (n = 5) of cases there were no common pathogens. In 29% (n = 13) of cases there were more pathogens in the soft-tissue specimens; these microorganisms included microbes isolated from bone cultures. In four patients (9%) with culture-positive soft-tissue specimens, bone culture specimens remained sterile. In one patient (2%) with culture-positive bone specimen, soft-tissue specimen remained sterile. Conclusion: Culture specimens should be obtained from both the bone and the overlying deep soft tissue in patients with suspected osteomyelitis whose clinical conditions are suitable. The decision to administer antibiotic therapy should depend on these results. (J Am Podiatr Med Assoc 98(4): 290–295, 2008)


1999 ◽  
Vol 48 (4) ◽  
pp. 1130-1132
Author(s):  
Tomoaki Horikawa ◽  
Kensuke Yonemura ◽  
Kimiaki Nishida ◽  
Toshitake Yakushiji ◽  
Teiji Kato ◽  
...  
Keyword(s):  

1984 ◽  
Vol 33 (2) ◽  
pp. 541-547
Author(s):  
Katsuji Shimizu ◽  
Goro Awaya ◽  
Fumihide Matsuda ◽  
Shigeaki Wakita ◽  
Masaki Maekawa ◽  
...  

1995 ◽  
Vol 14 (11) ◽  
pp. 1002-1004 ◽  
Author(s):  
P. Kragsbjerg ◽  
T. Norén ◽  
B. Söderquist

2010 ◽  
Vol 124 (9) ◽  
pp. 1017-1020 ◽  
Author(s):  
A Toth ◽  
T Nemeth ◽  
A Szucs ◽  
Z Szollosi ◽  
I Sziklai

AbstractObjective:To describe the first published case of superficial angiomyxoma with an epithelial component occurring in the retropharynx.Method:Case report of a patient with swallowing difficulties caused by a rare case of superficial angiomyxoma in the retropharynx.Results:Superficial angiomyxoma is a distinct entity among the dermal myxomatous lesions. Superficial angiomyxoma is poorly circumscribed, and local recurrence is common unless the tumour is excised with clear margins. Distinctive histological features include a myxoid mass composed of spindle and stellate-shaped cells and occasional multinucleated cells. There is prominent vasculature and a mixed inflammatory infiltrate in the stroma, particularly by neutrophil polymorphs. Epithelial structures are seen in about one-third of cases. A case of retropharyngeal tumour with morphological features of superficial angiomyxoma is reported. The tumour cells, including multinucleated ones, were negative for soft tissue differentiation markers. The inflammatory cells included lymphocytes, histiocytes and neutrophil polymorphs.Conclusion:This case demonstrates that a cutaneous type of angiomyxoma with epithelial-lined structures can occur in deep soft tissue, such as the retropharynx.


2002 ◽  
Vol 126 (4) ◽  
pp. 468-470 ◽  
Author(s):  
Tetsuji Yamamoto ◽  
Rieko Minami ◽  
Chiho Ohbayashi ◽  
Mayumi Inaba

Abstract Epithelioid leiomyosarcoma in the external deep soft tissue is extremely rare. Most epithelioid leiomyosarcomas occur in the uterus. We present a case of epithelioid leiomyosarcoma occurring in the muscle of the thigh of a 78-year-old man. Histologically, the tumor predominantly consisted of round or polygonal cells arranged in sheets with a focal spindle cell component. Immunohistochemical analysis revealed that the tumor cells expressed vimentin, α-smooth muscle actin, and α-sarcomeric actin. The tumor was negative for desmin, S100 protein, glial fibrillary acidic protein, pan-keratin, epithelial membrane antigen, CAM 5.2, HMB-45, leukocyte common antigen, factor VIII–associated antigen, and CD34. Electron microscopically, some tumor cells contained abundant actin-type filaments in their cytoplasm.


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