Synthesis and biological evaluation of 3-(4-fluorophenyl)-1H-pyrazole derivatives as androgen receptor antagonists

Anti-Cancer Drugs ◽

10.1097/cad.0000000000000322 ◽

2016 ◽

Vol 27 (4) ◽

pp. 278-285 ◽

Author(s):

Guangzhu Guo ◽

Jianzhen Liu ◽

Guanjie Wang ◽

Daoguang Zhang ◽

Jinjie Lu ◽

...

Keyword(s):

Androgen Receptor ◽

Biological Evaluation ◽

Pyrazole Derivatives ◽

Receptor Antagonists ◽

Synthesis And Biological Evaluation ◽

Androgen Receptor Antagonists

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Design, synthesis, and biological evaluation of 2-(5-methyl-1H-pyrazol-1-yl) acetamide derivatives as androgen receptor antagonists

Medicinal Chemistry Research ◽

10.1007/s00044-019-02291-y ◽

2019 ◽

Vol 28 (3) ◽

pp. 380-386

Author(s):

Junze Dong ◽

Jingya Zhang ◽

Zilu Li ◽

Solomon Asnake ◽

Daoguang Zhang ◽

...

Keyword(s):

Androgen Receptor ◽

Biological Evaluation ◽

Receptor Antagonists ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Androgen Receptor Antagonists

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Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17β-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2017.05.078 ◽

2017 ◽

Vol 27 (17) ◽

pp. 4212-4217 ◽

Author(s):

Kejing Lao ◽

Jie Sun ◽

Chong Wang ◽

Ying Wang ◽

Qidong You ◽

...

Keyword(s):

Androgen Receptor ◽

Biological Evaluation ◽

Receptor Antagonists ◽

Design Synthesis ◽

Reductase Inhibitors ◽

Amide Derivatives ◽

Synthesis And Biological Evaluation ◽

Androgen Receptor Antagonists

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Design, synthesis, and biological evaluation of 3-aryl-3-hydroxy-1-phenylpyrrolidine derivatives as novel androgen receptor antagonists

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2012.11.001 ◽

2013 ◽

Vol 21 (1) ◽

pp. 70-83 ◽

Author(s):

Satoshi Yamamoto ◽

Hiromi Kobayashi ◽

Tomohiro Kaku ◽

Katsuji Aikawa ◽

Takahito Hara ◽

...

Keyword(s):

Androgen Receptor ◽

Biological Evaluation ◽

Receptor Antagonists ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Androgen Receptor Antagonists

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ChemInform Abstract: Synthesis and Biological Evaluation of Amino-Pyridines as Androgen Receptor Antagonists for Stimulating Hair Growth and Reducing Sebum Production.

10.1002/chin.200804147 ◽

2008 ◽

Vol 39 (4) ◽

Author(s):

Lain-Yen Hu ◽

et al. et al.

Keyword(s):

Androgen Receptor ◽

Hair Growth ◽

Biological Evaluation ◽

Receptor Antagonists ◽

Sebum Production ◽

Synthesis And Biological Evaluation ◽

Androgen Receptor Antagonists

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Design, synthesis, and biological evaluation of 4-arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as novel androgen receptor antagonists

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2012.02.005 ◽

2012 ◽

Vol 20 (7) ◽

pp. 2338-2352 ◽

Author(s):

Satoshi Yamamoto ◽

Naoki Tomita ◽

Yuri Suzuki ◽

Tomohiko Suzaki ◽

Tomohiro Kaku ◽

...

Keyword(s):

Androgen Receptor ◽

Biological Evaluation ◽

Receptor Antagonists ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Androgen Receptor Antagonists

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Design, synthesis, and biological evaluation of novel androst-17β-amide structurally related compounds as dual 5α-reductase inhibitors and androgen receptor antagonists

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756366.2019.1654469 ◽

2019 ◽

Vol 34 (1) ◽

pp. 1597-1606 ◽

Author(s):

Kejing Lao ◽

Guoliang Xun ◽

Xingchun Gou ◽

Hua Xiang

Keyword(s):

Androgen Receptor ◽

Biological Evaluation ◽

Receptor Antagonists ◽

Design Synthesis ◽

Reductase Inhibitors ◽

Synthesis And Biological Evaluation ◽

Related Compounds ◽

Androgen Receptor Antagonists

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Design, synthesis and biological evaluation of novel 5-oxo-2-thioxoimidazolidine derivatives as potent androgen receptor antagonists

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2015.05.039 ◽

2015 ◽

Vol 99 ◽

pp. 51-66 ◽

Author(s):

Alexandre V. Ivachtchenko ◽

Yan A. Ivanenkov ◽

Oleg D. Mitkin ◽

Anton A. Vorobiev ◽

Irina V. Kuznetsova ◽

...

Keyword(s):

Androgen Receptor ◽

Biological Evaluation ◽

Receptor Antagonists ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Androgen Receptor Antagonists

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Design, synthesis and biological evaluation of novel thiohydantoin derivatives as potent androgen receptor antagonists for the treatment of prostate cancer

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2020.115953 ◽

2021 ◽

Vol 31 ◽

pp. 115953

Author(s):

Ao Wang ◽

Yawan Wang ◽

Xin Meng ◽

Yushe Yang

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Biological Evaluation ◽

Receptor Antagonists ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Androgen Receptor Antagonists

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Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2007.07.059 ◽

2007 ◽

Vol 17 (20) ◽

pp. 5693-5697 ◽

Author(s):

Lain-Yen Hu ◽

Huangshu John Lei ◽

Daniel Du ◽

Theodore R. Johnson ◽

Victor Fedij ◽

...

Keyword(s):

Androgen Receptor ◽

Hair Growth ◽

Biological Evaluation ◽

Receptor Antagonists ◽

Sebum Production ◽

Synthesis And Biological Evaluation ◽

Androgen Receptor Antagonists

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Design, synthesis, and biological evaluation of 4-phenylpyrrole derivatives as novel androgen receptor antagonists

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2011.10.067 ◽

2012 ◽

Vol 20 (1) ◽

pp. 422-434 ◽

Author(s):

Satoshi Yamamoto ◽

Nobuyuki Matsunaga ◽

Takenori Hitaka ◽

Masami Yamada ◽

Takahito Hara ◽

...

Keyword(s):

Androgen Receptor ◽

Biological Evaluation ◽

Receptor Antagonists ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Androgen Receptor Antagonists

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