The role of opioidergic system in modulating cost/benefit decision-making in alcohol-preferring AA rats and Wistar rats

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Ville Oinio ◽  
Mikko Sundström ◽  
Pia Bäckström ◽  
Johanna Uhari-Väänänen ◽  
Kalervo Kiianmaa ◽  
...  
2020 ◽  
Author(s):  
Arish Mudra Rakshasa ◽  
Michelle T. Tong

AbstractChronic stress can impact decision-making and lead to a preference for immediate rewards rather than long-term payoffs. Factors that may mitigate these effects of chronic stress on decision-making are under-explored. Here we used a mouse model to investigate the changes in decision-making caused by the experience of chronic stress and the role of social interaction in attenuating these changes. To test decision-making, mice were trained to perform a Cost-Benefit Conflict (CBC) task on a T-maze, in which they could choose between a high-reward, high-risk alternative and a low-reward, low-risk alternative. Mice were either housed in groups or alone throughout the experiment. Both groups of mice underwent a seven-day period of repeated immobilisation to induce chronic stress. Stress levels were confirmed using behavioural (open field test) and physiological (urine corticosterone ELISA) measures. We found a significant increase in frequency of high-risk decisions after exposure to chronic stress among both socially- and individually-housed mice. Crucially, socially-housed mice showed a significantly smaller increase in high-risk decision-making compared to singly-housed mice. These findings suggest that although chronic stress leads to an increase in high-risk decision-making in mice, access to social interaction may mitigate this stress effect.


2018 ◽  
Vol 41 ◽  
Author(s):  
Kevin Arceneaux

AbstractIntuitions guide decision-making, and looking to the evolutionary history of humans illuminates why some behavioral responses are more intuitive than others. Yet a place remains for cognitive processes to second-guess intuitive responses – that is, to be reflective – and individual differences abound in automatic, intuitive processing as well.


2014 ◽  
Vol 21 (1) ◽  
pp. 15-23 ◽  
Author(s):  
Helen Pryce ◽  
Amanda Hall

Shared decision-making (SDM), a component of patient-centered care, is the process in which the clinician and patient both participate in decision-making about treatment; information is shared between the parties and both agree with the decision. Shared decision-making is appropriate for health care conditions in which there is more than one evidence-based treatment or management option that have different benefits and risks. The patient's involvement ensures that the decisions regarding treatment are sensitive to the patient's values and preferences. Audiologic rehabilitation requires substantial behavior changes on the part of patients and includes benefits to their communication as well as compromises and potential risks. This article identifies the importance of shared decision-making in audiologic rehabilitation and the changes required to implement it effectively.


2009 ◽  
Vol 00 (00) ◽  
pp. 090930024626018-7
Author(s):  
Shyam S. Agrawal ◽  
Sibi P. Ittiyavirah
Keyword(s):  

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