Restoring vaginal function in postmenopausal women with genitourinary syndrome of menopause

2018 ◽  
Vol 25 (1) ◽  
pp. 106-108 ◽  
Author(s):  
Risa Kagan ◽  
Eliza Rivera
Keyword(s):  
Postmenopausal Women ◽  
Genitourinary Syndrome Of Menopause ◽  
Genitourinary Syndrome

scholarly journals Genitourinary syndrome of menopause. Prevalence and quality of life in Spanish postmenopausal women. The GENISSE study

Climacteric ◽  
2018 ◽  
Vol 21 (2) ◽  
pp. 167-173 ◽  
Author(s):  
E. Moral ◽  
J. L. Delgado ◽  
F. Carmona ◽  
B. Caballero ◽  
C. Guillán ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Postmenopausal Women ◽  
Genitourinary Syndrome Of Menopause ◽  
Genitourinary Syndrome

scholarly journals Local treatment with a polycarbophil-based cream in postmenopausal women with genitourinary syndrome of menopause

2020 ◽  
Author(s):  
Tipatai Yodplob ◽  
Kun Sirisopana ◽  
Mutita Jongwannasiri ◽  
Pokket Sirisreetreerux ◽  
Wit Viseshsindh ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Local Treatment ◽  
Genitourinary Syndrome Of Menopause ◽  
Genitourinary Syndrome

The experience of genitourinary syndrome of menopause (GSM) among Thai postmenopausal women: the non-reporting issue

2019 ◽  
Vol 30 (11) ◽  
pp. 1843-1847 ◽  
Author(s):  
Sasivimol Srisukho ◽  
Tawiwan Pantasri ◽  
Wirawit Piyamongkol ◽  
Chailert Phongnarisorn ◽  
Nuntana Morakote
Keyword(s):  
Postmenopausal Women ◽  
Genitourinary Syndrome Of Menopause ◽  
Genitourinary Syndrome

Vaginal Microbiota in postmenopausal women treated with pulsed CO 2 laser for genitourinary syndrome of menopause (GSM)

Maturitas ◽  
2017 ◽  
Vol 100 ◽  
pp. 198
Author(s):  
Stefano Salvatore ◽  
Filippo Verri ◽  
Serena Girardelli ◽  
Eleonora Iachini ◽  
Nicasio Mancini ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Vaginal Microbiota ◽  
Genitourinary Syndrome Of Menopause ◽  
Genitourinary Syndrome

Association of Vaginal Microbiota with Signs and Symptoms of the Genitourinary Syndrome of Menopause across Reproductive Stages

2021 ◽  
Author(s):  
Michelle Shardell ◽  
Patti E Gravitt ◽  
Anne E Burke ◽  
Jacques Ravel ◽  
Rebecca M Brotman
Keyword(s):  
Postmenopausal Women ◽  
Female Genital Tract ◽  
Premenopausal Women ◽  
Signs And Symptoms ◽  
Amplicon Sequencing ◽  
Vaginal Microbiota ◽  
Gardnerella Vaginalis ◽  
Rrna Gene ◽  
Genitourinary Syndrome Of Menopause ◽  
Genitourinary Syndrome

Abstract The genitourinary syndrome of menopause (GSM) describes signs and symptoms resulting from effects of estrogen deficiency on the female genitourinary tract, including the vagina, labia, urethra, and bladder. Signs/symptoms associated with GSM may occur during any reproductive stage from multiple etiologies but are most common during menopause due to low estrogen. Vaginal microbiota, particularly Lactobacillus spp., are beneficial to the female genital tract; however, their abundance declines during menopause. We aimed to longitudinally assess vaginal microbiota characterized by 16S rRNA gene amplicon sequencing and GSM-associated endpoints across reproductive stages. In a two-year cohort study of 750 women aged 35-60 years at enrollment and 2,111 semiannual person-visits, low-Lactobacillus vaginal microbiota communities were observed at 21.2% (169/798), 22.9% (137/597), and 49.7% (356/716) of person-visits among pre-, peri-, and postmenopausal women, respectively (p<.001). Compared to communities that have high Gardnerella vaginalis relative abundance and diverse anaerobes, the following communities were associated with a lower covariate-adjusted odds of vaginal atrophy: L. crispatus-dominated communities among postmenopausal women (odds ratio[OR]=0.25; 95% confidence interval[CI], 0.08, 0.81), L. gasseri/L. jensenii (OR=0.21; 95%CI, 0.05, 0.94) and L. iners (OR=0.21; 95%CI, 0.05, 0.85) among perimenopausal women, and L. iners-dominated communities (OR=0.18; 95%CI, 0.04, 0.76) among premenopausal women. Postmenopausal women with L. gasseri/L. jensenii-dominated communities had the lowest odds of vaginal dryness (OR=0.36; 95%CI, 0.12, 1.06) and low libido (OR=0.28; 95%CI, 0.10, 0.74). Findings for urinary incontinence were inconsistent. Associations of vaginal microbiota with GSM signs/symptoms are most evident after menopause, suggesting an avenue for treatment and prevention.

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