Prognostic and Predictive Value of Epidermal Growth Factor Receptor Tyrosine Kinase Domain Mutation Status and Gene Copy Number for Adjuvant Chemotherapy in Non-small Cell Lung Cancer

Gene Copy Number ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Gene Copy ◽

Tyrosine Kinase Domain ◽

Small Cell Lung ◽

Mutation Status ◽

Kinase Domain Mutation ◽

Gefitinib-Sensitive Mutations of the Epidermal Growth Factor Receptor Tyrosine Kinase Domain in Chinese Patients with Non–Small Cell Lung Cancer

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-04-2506 ◽

2005 ◽

Vol 11 (12) ◽

pp. 4289-4294 ◽

Cited By ~ 90

Author(s):

Xin Lin Mu ◽

Long Yun Li ◽

Xiao Tong Zhang ◽

Men Zhao Wang ◽

Rui E. Feng ◽

...

Keyword(s):

Lung Cancer ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Small Cell ◽

Chinese Patients ◽

Tyrosine Kinase Domain ◽

Small Cell Lung ◽

Mutations of the epidermal growth factor receptor tyrosine kinase domain and associations with clinicopathological features in non-small cell lung cancer patients

Lung Cancer ◽

10.1016/j.lungcan.2005.12.015 ◽

2006 ◽

Vol 52 (2) ◽

pp. 225-233 ◽

Cited By ~ 22

Author(s):

S. Murray ◽

E. Timotheadou ◽

H. Linardou ◽

A.V. Vrettou ◽

I. Kostopoulos ◽

...

Keyword(s):

Lung Cancer ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Small Cell ◽

Clinicopathological Features ◽

Tyrosine Kinase Domain ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

P1-024: Relationship between tyrosine kinase domain gene mutations of epidermal growth factor receptor and respiratory function in non-small cell lung cancer

Journal of Thoracic Oncology ◽

10.1097/01.jto.0000283638.97101.d2 ◽

2007 ◽

Vol 2 (8) ◽

pp. S559

Author(s):

Kouki Ohtsuka ◽

Hiroaki Ohnishi ◽

Keiko Morita ◽

Misaki Chiba ◽

Wataru Ogura ◽

...

Keyword(s):

Lung Cancer ◽

Respiratory Function ◽

Growth Factor Receptor ◽

Gene Mutations ◽

Kinase Domain ◽

Small Cell ◽

Tyrosine Kinase Domain ◽

Small Cell Lung ◽

Mutation in the tyrosine kinase domain of epidermal growth factor receptor is a predictive and prognostic factor for gefitinib treatment in patients with non-small cell lung cancer

Journal of Clinical Oncology ◽

10.1200/jco.2005.23.16_suppl.7086 ◽

2005 ◽

Vol 23 (16_suppl) ◽

pp. 7086-7086

Author(s):

C.-M. Tsai ◽

C.-H. Chiu ◽

T.-Y. Chou ◽

L.-H. Li ◽

C.-Y. Hsiao ◽

...

Keyword(s):

Lung Cancer ◽

Prognostic Factor ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Small Cell ◽

Tyrosine Kinase Domain ◽

Small Cell Lung ◽

Gefitinib Treatment ◽

Increased epidermal growth factor receptor (EGFR) gene copy number is strongly associated with EGFR mutations and adenocarcinoma in non-small cell lung cancers: A chromogenic in situ hybridization study of 182 patients

Lung Cancer ◽

10.1016/j.lungcan.2008.01.009 ◽

2008 ◽

Vol 61 (3) ◽

pp. 328-339 ◽

Cited By ~ 34

Author(s):

John Wen-Cheng Chang ◽

Hui-Ping Liu ◽

Meng-Heng Hsieh ◽

Yueh-Fu Fang ◽

Meng-Shu Hsieh ◽

...

Keyword(s):

Gene Copy Number ◽

Growth Factor Receptor ◽

Small Cell ◽

Egfr Mutations ◽

Gene Copy ◽

Hybridization Study ◽

Small Cell Lung ◽

Lung Cancers ◽

Increased HER2 Gene Copy Number Is Associated With Response to Gefitinib Therapy in Epidermal Growth Factor Receptor-Positive Non-Small-Cell Lung Cancer Patients

Yearbook of Oncology ◽

10.1016/s1040-1741(08)70162-3 ◽

2006 ◽

Vol 2006 ◽

pp. 229-231

Author(s):

N.H. Hanna

Keyword(s):

Lung Cancer ◽

Copy Number ◽

Gene Copy Number ◽

Growth Factor Receptor ◽

Small Cell ◽

Gene Copy ◽

Small Cell Lung ◽

Her2 Gene ◽

Lung Cancer Patients ◽

Antibodies against highly conserved sites in the epidermal growth factor receptor tyrosine kinase domain as probes for structure and function

Biochemistry ◽

10.1021/bi00068a025 ◽

1993 ◽

Vol 32 (17) ◽

pp. 4659-4664 ◽

Cited By ~ 2

Author(s):

Nancy A. Brown ◽

Larry A. Compton ◽

Gail M. Clinton

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Structure And Function ◽

Tyrosine Kinase Domain ◽

Epidermal Growth ◽

And Function

Somatic Mutations in the Tyrosine Kinase Domain of Epidermal Growth Factor Receptor (EGFR) Abrogate EGFR-Mediated Radioprotection in Non–Small Cell Lung Carcinoma

Cancer Research ◽

10.1158/0008-5472.can-07-0242 ◽

2007 ◽

Vol 67 (11) ◽

pp. 5267-5274 ◽

Cited By ~ 107

Author(s):

Amit K. Das ◽

Benjamin P. Chen ◽

Michael D. Story ◽

Mitsuo Sato ◽

John D. Minna ◽

...

Keyword(s):

Somatic Mutations ◽

Small Cell Lung Carcinoma ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Small Cell ◽

Tyrosine Kinase Domain ◽

Small Cell Lung ◽

Cell Lung Carcinoma ◽

Somatic Mutations of the Tyrosine Kinase Domain of Epidermal Growth Factor Receptor and Tyrosine Kinase Inhibitor Response to TKIs in Non-small Cell Lung Cancer: An Analytical Database

Journal of Thoracic Oncology ◽

10.1097/jto.0b013e31818071f3 ◽

2008 ◽

Vol 3 (8) ◽

pp. 832-839 ◽

Cited By ~ 86

Author(s):

Samuel Murray ◽

Issa J. Dahabreh ◽

Helena Linardou ◽

Menelaos Manoloukos ◽

Dimitrios Bafaloukos ◽

...

Keyword(s):

Lung Cancer ◽

Tyrosine Kinase ◽

Somatic Mutations ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Small Cell ◽

Tyrosine Kinase Domain ◽

Small Cell Lung ◽

Epidermal growth factor receptor gene copy number and protein level are not associated with outcome of non-small-cell lung cancer patients treated with chemotherapy

Annals of Oncology ◽

10.1093/annonc/mdl407 ◽

2007 ◽

Vol 18 (3) ◽

pp. 447-452 ◽

Cited By ~ 34

Author(s):

R. Dziadziuszko ◽

B. Holm ◽

B.G. Skov ◽

K. Osterlind ◽

M.V. Sellers ◽

...

Keyword(s):

Lung Cancer ◽

Copy Number ◽

Receptor Gene ◽

Gene Copy Number ◽

Growth Factor Receptor ◽

Small Cell ◽

Gene Copy ◽

Small Cell Lung ◽

Lung Cancer Patients ◽