scholarly journals Effects of smoking on delayed neuropsychiatric sequelae in acute carbon monoxide poisoning

Medicine ◽  
2021 ◽  
Vol 100 (20) ◽  
pp. e26032
Author(s):  
Sangun Nah ◽  
Sungwoo Choi ◽  
Sun-Uk Lee ◽  
Gi Woon Kim ◽  
Young Hwan Lee ◽  
...  
2013 ◽  
Vol 14 (1) ◽  
Author(s):  
Mounia Rahmani ◽  
Halima Belaidi ◽  
Maria Benabdeljlil ◽  
Wafa Bouchhab ◽  
Nadia El Jazouli ◽  
...  

1989 ◽  
Vol 45 (2-3) ◽  
pp. 207-213 ◽  
Author(s):  
David G. Penney ◽  
Kuldeep Verma ◽  
Julie A. Hull

The Lancet ◽  
1940 ◽  
Vol 236 (6118) ◽  
pp. 677-679
Author(s):  
J MCMICHAEL

2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Shu-Chen Liao ◽  
Yan-Chiao Mao ◽  
Yao-Min Hung ◽  
Ching-Hsing Lee ◽  
Chen-Chang Yang

Objective. Delayed neuropsychiatric sequelae (DNS) are serious complications of carbon monoxide (CO) poisoning that adversely affect poisoned patients’ quality of life as well as socioeconomic status. This study aimed to determine clinical predictors of DNS in patients with CO poisoning. Methods. This retrospective study included all CO-poisoned patients admitted to the emergency department (ED) of Linkou Chang Gung Memorial Hospital in Taiwan from 1 January 2009 to 31 December 2015. The medical records of all patients with CO poisoning were carefully reviewed, and relevant data were abstracted into a standardised form. Univariate and multivariate logistic regression models were used to identify predictors of DNS after CO poisoning. Receiver operating characteristic (ROC) curve analysis was used to determine the ideal cut-off value for continuous variables that predict the development of DNS. Results. A total of 760 patients with CO poisoning were identified during the study period. Among them, 466 were eligible for the analysis of predictors of DNS. In multivariate analysis, Glasgow Coma Scale <9 (odds ratio [OR], 2.74; 95% confidence interval [CI], 1.21–6.21), transient loss of consciousness (OR, 3.59; 95% CI, 1.31–9.79), longer duration from CO exposure to ED presentation (OR, 1.05; 95% CI, 1.03–1.08), and corrected QT (QTc) prolongation (OR, 2.61; 95% CI, 1.21–5.61) were found to be associated with a higher risk of DNS. The area under the ROC curve (AUC) for QTc interval measured within 6 h after exposure best predicted the development of DNS, with a result of 0.729 (95% CI 0.660–0.791). Moreover, the best cut-off value of the QTc interval was 471 ms, with a sensitivity of 53.3% and a specificity of 85.1%. Conclusions. We identified several potential predictors of DNS following CO poisoning. Among them, QTc prolongation found within 6 h after exposure is a novel predictor of DNS, which may be helpful in the future care of patients with CO poisoning.


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