De-escalation of biological therapy in inflammatory bowel disease patients following prior dose escalation

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Pepijn W. A. Thomas ◽  
Lisa J. T. Smits ◽  
Maarten Te Groen ◽  
Rachel L. West ◽  
Maurice G. V. M. Russel ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Dose Escalation ◽  
Bowel Disease ◽  
Biological Therapy ◽  
Inflammatory Bowel

Preoperative biological therapy and short-term outcomes of abdominal surgery in patients with inflammatory bowel disease

Gut ◽  
2012 ◽  
Vol 62 (3) ◽  
pp. 387-394 ◽  
Author(s):  
Matti Waterman ◽  
Wei Xu ◽  
Amreen Dinani ◽  
A Hillary Steinhart ◽  
Kenneth Croitoru ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Abdominal Surgery ◽  
Bowel Disease ◽  
Biological Therapy ◽  
Short Term ◽  
Inflammatory Bowel

scholarly journals OUTCOMES OF DOSE ESCALATION WITH ADALIMUMAB (ADA) IN INFLAMMATORY BOWEL DISEASE

Gut ◽  
2013 ◽  
Vol 62 (Suppl 2) ◽  
pp. A42.3-A43
Author(s):  
A Dillon ◽  
C Rowan ◽  
D Gibson ◽  
D Keegan ◽  
K Byrne ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Dose Escalation ◽  
Bowel Disease ◽  
Inflammatory Bowel

scholarly journals FACTORS ASSOCIATED WITH PATIENT´S PREFERENCE IN CHOOSING THEIR THERAPY FOR INFLAMMATORY BOWEL DISEASE IN BRAZIL

2020 ◽  
Vol 57 (4) ◽  
pp. 491-497
Author(s):  
Adhan Amenomori WU ◽  
Jaqueline Ribeiro de BARROS ◽  
Madhoor RAMDEEN ◽  
Julio Pinheiro BAIMA ◽  
Rogerio SAAD-HOSSNE ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Biological Therapy ◽  
Oral Route ◽  
New Drugs ◽  
Cross Sectional ◽  
Mode Of Administration ◽  
Mode Of Application ◽  
Inflammatory Bowel

BACKGROUND: Biological therapy and new drugs have revolutionized the treatment of inflammatory bowel disease. Ideally, the choice of medication should be a shared decision with the patient, aiming at greater satisfaction, compliance, and consequently, favorable clinical outcome. OBJECTIVE: This study aims to evaluate patient’s preferences in the choice of their therapy and the factors that influence this choice. METHODS: This cross-sectional study enrolled 101 outpatients with Crohn’s disease or ulcerative colitis. The inclusion criteria were age ≥18 years and no previous exposure to biological therapy. Patients’ preferences were assessed through questions that addressed the preferred mode of administration (oral, subcutaneous, or intravenous) and the factors that determined the choice of medication (efficacy, medical indication, fear of medication, convenience, mode of application, and personal doctors’ indication). RESULTS: The mean age was 43.6±13.5 years, 75.3% were female, and 81.2% were cases of ulcerative colitis. Regarding the mode of administration, the majority of patients preferred oral (87.1%), followed by intravenous (6.93%) and subcutaneous (5.94%) medications. The reasons were “I prefer to take it at home” (42.57%), “I have more freedom” (36.63%), “I don’t like self-application” (29.70%), and “I believe it works better” (19.80%). Younger patients and patients in clinical disease activity preferred intravenous mode compared to the oral route (P<0.05). Doctor’s opinion (98%) was an important factor associated with the medication choice. CONCLUSION: Oral route was the preferred mode of administration and most patients took their physician’s opinion into account in their choice of medication.

Safety of Sequential Biological Therapy in Inflammatory Bowel Disease: Results From a Tertiary Referral Centre

2021 ◽  
Author(s):  
Annick Moens ◽  
Nasim Sadat Seyed Tabib ◽  
Vera Ballet ◽  
João Sabino ◽  
Séverine Vermeire ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Biological Therapy ◽  
Referral Centre ◽  
Tertiary Referral ◽  
Tertiary Referral Centre ◽  
Inflammatory Bowel

scholarly journals Mo1740 OPTICAL ENHANCEMENT AND PROBE CONFOCAL LASER ENDOMICROSCOPY CAN ACCURATELY PREDICT RESPONSE TO BIOLOGICAL THERAPY IN INFLAMMATORY BOWEL DISEASE PATIENTS

2020 ◽  
Vol 91 (6) ◽  
pp. AB476
Author(s):  
Marietta Iacucci ◽  
Olga Maria Nardone ◽  
Samuel C. Smith ◽  
Alina Bazarova ◽  
Rosanna Cannatelli ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Biological Therapy ◽  
Confocal Laser Endomicroscopy ◽  
Confocal Laser ◽  
Inflammatory Bowel
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