Fraternal Coopers Develop Sinonasal Intestinal-Type Adenocarcinoma

2021 ◽  
Vol 26 (4) ◽  
pp. 252-255
Author(s):  
Wesley D. Mallinger ◽  
Paul W. Read ◽  
Edward B. Stelow
2017 ◽  
Vol 24 (1) ◽  
pp. 55 ◽  
Author(s):  
C. Jain ◽  
L. Caulley ◽  
K.I. Macdonald ◽  
B. Purgina ◽  
C.K. Lai ◽  
...  

Background Non-intestinal-type adenocarcinoma is a malignancy traditionally found in the sinonasal cavity. To our knowledge, this case is the first reported of this rare condition originating in the nasopharynx.Case Presentation A 67-year-old woman with nasopharyngeal non-intestinal-type adenocarcinoma, with an accompanying parapharyngeal mass received primary radiation treatment for both lesions. Her tumour subsequently persisted, with a concomitant conversion in pathology from a low- to a high-grade malignancy.Results Non-intestinal-type and intestinal-type adenocarcinomas of the nasopharynx are extremely rare tumours and do not appear in the World Health Organization classification system. We review the pathophysiologic features of these malignancies and propose modifications to the current classification system.Conclusions Non-intestinal-type adenocarcinoma should be included in the differential diagnosis of nasopharyngeal masses. In our experience, this tumour in this location showed a partial response to primary radiation but later converted from a low- to a high-grade adenocarcinoma.


2018 ◽  
Vol 32 (4) ◽  
pp. 568-575 ◽  
Author(s):  
Taiki Hashimoto ◽  
Reiko Ogawa ◽  
Tzu-Yin Tang ◽  
Hiroshi Yoshida ◽  
Hirokazu Taniguchi ◽  
...  

2018 ◽  
Vol 120 ◽  
pp. e962-e969 ◽  
Author(s):  
Maurizio Bignami ◽  
Davide Lepera ◽  
Luca Volpi ◽  
Alessia Lambertoni ◽  
Alberto Arosio ◽  
...  

Head & Neck ◽  
2013 ◽  
Vol 36 (5) ◽  
pp. E44-E47 ◽  
Author(s):  
Diana Bell ◽  
Floyd Christopher Holsinger ◽  
Nelson Ordonez ◽  
Adel K. El-Naggar

1993 ◽  
Vol 79 (3) ◽  
pp. 205-210 ◽  
Author(s):  
Carmelo Urso ◽  
Maria Benedetta Ninu ◽  
Alessandro Franchi ◽  
Milena Paglierani ◽  
Roberto Bondi

Background Intestinal-type adenocarcinoma (ITAC) of the nose and paranasal sinuses is a relatively rare tumor. It commonly affects subjects exposed to wood or leather dust. Methods The authors present the clinicopathologic findings of 18 cases of sinonasal ITACs and review the proposed histologic classifications. Results All patients, except one, were males; mean age was 60 years (range, 41-79); in 9 cases an occupational exposure to wood or leather dust was found. Common presenting symptoms were epistaxis, nasal obstruction and rhinorrhea. Histologically, tumors were divided into four groups: well-differentiated (G1) ITACs = 3 cases; moderately differentiated (G2) ITACs = 8 cases; poorly differentiated (G3) ITACs = 2 cases; mucinous (M) ITACs = 5 cases. Immunocytochemically, 16/17 cases were positive for carcinoembryonal antigen, 1/17 for somatostatin, and 0/16 cases for gastrin. Conclusions Sinonasal ITACs are aggressive tumors, often diagnosed in a relatively advanced stage. Owing the close similarity of the microscopic aspects, a histologic classification of ITACs analogous to that of colonic adenocarcinomas is proposed.


1991 ◽  
Vol 15 (4) ◽  
pp. 368-375 ◽  
Author(s):  
Douglas W. Franquemont ◽  
Robert E. Fechner ◽  
Stacey E. Mills

2017 ◽  
Vol 38 (9) ◽  
pp. e364-e368 ◽  
Author(s):  
Marc-Elie Nader ◽  
Diana Bell ◽  
Lawrence Ginsberg ◽  
Franco DeMonte ◽  
G. Brandon Gunn ◽  
...  

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