scholarly journals Preliminary evidence for the role of HTR2A variants in binge eating in young women

2014 ◽  
Vol 24 (1) ◽  
pp. 28-33 ◽  
Author(s):  
Rachel Koren ◽  
Alexis E. Duncan ◽  
Melissa A. Munn-Chernoff ◽  
Kathleen K. Bucholz ◽  
Michael T. Lynskey ◽  
...  
Life ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 508
Author(s):  
Robert K. Townsend ◽  
Kyle M. Fargen

Idiopathic intracranial hypertension (IIH) is a debilitating condition that has traditionally been difficult to treat. In recent years, there has been increasing focus on the role of intracranial venous hypertension in the pathophysiology of IIH. Based on increased understanding of this pathophysiology, venous sinus stenting (VSS) has emerged as a safe and reliable treatment for a certain population of patients with IIH. Stratifying patients with IIH based on the status of their venous outflow can provide insight into which patients may enjoy reduction in their symptoms after VSS and provides information regarding why some patients may have symptom recurrence. The traditional view of IIH as a disease due to obesity in young women has been cast into doubt as the understanding of the role of intracranial venous hypertension has improved.


2020 ◽  
pp. 193229682097640
Author(s):  
Michelle Dugas ◽  
Weiguang Wang ◽  
Kenyon Crowley ◽  
Anand K. Iyer ◽  
Malinda Peeples ◽  
...  

Background: Digital health solutions targeting diabetes self-care are popular and promising, but important questions remain about how these tools can most effectively help patients. Consistent with evidence of the salutary effects of note-taking in education, features that enable annotation of structured data entry might enhance the meaningfulness of the interaction, thereby promoting persistent use and benefits of a digital health solution. Method: To examine the potential benefits of note-taking, we explored how patients with type 2 diabetes used annotation features of a digital health solution and assessed the relationship between annotation and persistence in engagement as well as improvements in glycated hemoglobin (A1C). Secondary data from 3142 users of the BlueStar digital health solution collected between December 2013 and June 2017 were analyzed, with a subgroup of 372 reporting A1C lab values. Results: About a third of patients recorded annotations while using the platform. Annotation themes largely reflected self-management behaviors (diet, physical activity, medication adherence) and well-being (mood, health status). Early use of contextual annotations was associated with greater engagement over time and with greater improvements in A1C. Conclusions: Our research provides preliminary evidence of the benefits of annotation features in a digital health solution. Future research is needed to assess the causal impact of note-taking and the moderating role of thematic content reflected in notes.


Author(s):  
Dorota Czyżowska ◽  
Ewa Gurba ◽  
Natalia Czyżowska ◽  
Alicja Kalus ◽  
Katarzyna Sitnik-Warchulska ◽  
...  

The main research objective of this study was seeking the predictive role of closeness to parents, attachment, identity style, identity commitment, type of relationship, and having children in intimacy among young women and men. Many studies indicate differences in the level of engagement, communication, and satisfaction in relationships. The study group comprised 227 people, including 114 women (M = 29.99; SD = 4.36), and 113 men (M = 30.00; SD = 4.33). A total of 40% of the subjects were married, and the remaining 60% subjects were in informal relationships; 101 people had children and the other individuals were childless. The following instruments were used: The Miller Social Intimacy Scale, questionnaires to assess closeness and attachment, and the Identity Style Inventory. The significance of the differences and the stepwise regression analysis were performed. The results of the study demonstrated a higher level of intimacy in a relationship with a partner among women than men. The nature of a relationship does not matter to the sense of intimacy. However, closeness to parents during childhood and adolescence, the model of interpersonal relations, and the identity style are predictors of intimacy in a relationship. The study results can be used in creating preventive and educational programs focused on family life and satisfied relationships.


2012 ◽  
Vol 53 (6) ◽  
pp. 774-778 ◽  
Author(s):  
Raffaella Di Schiena ◽  
Olivier Luminet ◽  
Pierre Philippot ◽  
Céline Douilliez

Author(s):  
Saubhagya Kumar Jena ◽  
Lipsa Mishra ◽  
Sushree Samiksha Naik ◽  
Shahnawaz Khan

AbstractObjectiveTo explore the perception on PCOS and its prevalence among adolescent and young women.MethodsThe study was conducted over 2 year period in a tertiary care teaching hospital from Eastern India. A pre-formed, validated questionnaire was used to record the details. Descriptive statistics was used to report the findings.ResultsOf 965 young patients with mean (SD) age 20.64 (2.1) years, 27 (2.79 %) were aware of an entity called PCOS. Awareness among adolescents with PCOS was 25.9 % (7/27). All aware patients belonged to the urban sector with professionals constituting around 48%, of which 11% were students. The major source of information among aware patients was from doctors (40.7%), and friends and Internet (25.9%); rest being from books, newspapers, and teachers. Majority (70%) were aware that diet restriction and exercise were the primary modalities of treatment, whereas, only 3.7% knew about the role of contraceptive pills in PCOS.ConclusionsAwareness regarding PCOS among the young women is very low mainly in the rural set up. Doctors and health staffs should play a major role in spreading awareness of the entity to prevent long term complications.


2015 ◽  
Vol 23 (5) ◽  
pp. 413-416 ◽  
Author(s):  
Lies Depestele ◽  
Laurence Claes ◽  
Eva Dierckx ◽  
Imke Baetens ◽  
Katrien Schoevaerts ◽  
...  

2002 ◽  
Vol 44 (3) ◽  
pp. 1-14
Author(s):  
Penny Harwood ◽  
Caroline Davey

In the context of an increasingly pluralist and in some ways troubled society, work was undertaken to investigate the role of formal education and non-educational organisations in building good citizenship in girls and young women (9-19 years old). Different stages in the developmental process are identified, and the paper describes a number of ways in which experiential and attitudinal information was obtained from the range of respondents: these included a Citizen's Forum and quantitative omnibus research. Methodologies to involve the young people in focused and relevant debate during the one-day Forum were developed and are discussed.


2018 ◽  
Vol 14 (12) ◽  
pp. 20180642 ◽  
Author(s):  
Eiluned Pearce ◽  
Rafael Wlodarski ◽  
Anna Machin ◽  
Robin I. M. Dunbar

The ratio between the second and fourth digits (2D:4D) has been widely used as a proxy for fetal exposure to androgens and has been linked to a number of sociosexual traits in humans. However, the role of genes in this equation remains unknown. Here ( N = 474), we test, firstly, for associations between 2D:4D and single-nucleotide polymorphisms (SNPs) in nine neurochemical receptor genes ( AR, OXTR, AVPR1A, OPRM1, DRD1/2, ANKK1, 5HTR1A/2A ), and secondly, whether digit ratios mediate the relationship between genetic variation and sociosexuality. We demonstrate significant associations between AR , OPRM1 and AVPR1A and 2D:4D. Moreover, mediation analysis indicates that, in women, AR and OPRM1 variation drives digit ratios, which are related positively to impulsivity and, for OPRM1 , negatively to romantic relationship quality. Although these findings are subject to multiple testing issues, this study provides preliminary evidence that in women genetic factors may affect both impulsivity and perceived relationship quality through influencing factors indexed by digit ratios.


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