Preliminary Study on Machine Learning Application for Parkinson's Disease Diagnosis

2019 ◽  
Author(s):  
Ahmad Habbie Thias ◽  
Isca Amanda ◽  
Jessika ◽  
Navila Akhsanil Fitri ◽  
Raih Rona Althof ◽  
...  
Keyword(s):  
Machine Learning ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Disease Diagnosis ◽  
Preliminary Study

scholarly journals Cloud-Based Parkinson’s Disease Diagnosis Using Machine Learning

2021 ◽  
Vol 8 (6) ◽  
pp. 915-922
Author(s):  
Ahmed R. Nasser ◽  
Ali M. Mahmood
Keyword(s):  
Machine Learning ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Early Treatment ◽  
Intelligent System ◽  
Feature Selection Method ◽  
Disease Diagnosis ◽  
Classification Model ◽  
Accuracy Measurement ◽  
Diagnosis Model

Parkinson’s disease (PD) harms the human brain's nervous system and can affect the patient's life. However, the diagnosis of PD diagnosis in the first stages can lead to early treatment and save costs. In this paper, a cloud-based machine learning diagnosing intelligent system is proposed for the PD with respect to patient voice. The proposed system is composed of two stages. In the first stage, two machine learning approaches, Random-Forest (RF) and Long-Short-Term-Memory (LSTM) are applied to generate a model that can be used for early treatment of PD. In this stage, a feature selection method is used to choose the minimum subset of the best features, which can be utilized later to generate the classification model. In the second stage, the best diagnosis model is deployed in cloud computing. In this stage, an Android application is also designed to provide the interface to the diagnosis model. The performance evaluation of the diagnosis model is conducted based on the F-score accuracy measurement. The result shows that the LTSM model has superior accuracy with 95% of the F-score compared with the RF model. Therefore, the LSTM model is selected for implementing a cloud-based PD diagnosing application using Python and Java.

Machine Learning Approaches in Parkinson’s Disease

2021 ◽  
Vol 28 ◽  
Author(s):  
Annamaria Landolfi ◽  
Carlo Ricciardi ◽  
Leandro Donisi ◽  
Giuseppe Cesarelli ◽  
Jacopo Troisi ◽  
...  
Keyword(s):  
Machine Learning ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Neurodegenerative Disorder ◽  
Learning Algorithms ◽  
Disease Diagnosis ◽  
Machine Learning Algorithms ◽  
Clinical Aspects ◽  
Learning Approaches

Background:: Parkinson’s disease is the second most frequent neurodegenerative disorder. Its diagnosis is challenging and mainly relies on clinical aspects. At present, no biomarker is available to obtain a diagnosis of certainty in vivo. Objective:: The present review aims at describing machine learning algorithms as they have been variably applied to different aspects of Parkinson’s disease diagnosis and characterization. Methods:: A systematic search was conducted on PubMed in December 2019, resulting in 230 publications obtained with the following search query: “Machine Learning” “AND” “Parkinson Disease”. Results:: the obtained publications were divided into 6 categories, based on different application fields: “Gait Analysis - Motor Evaluation”, “Upper Limb Motor and Tremor Evaluation”, “Handwriting and typing evaluation”, “Speech and Phonation evaluation”, “Neuroimaging and Nuclear Medicine evaluation”, “Metabolomics application”, after excluding the papers of general topic. As a result, a total of 166 articles were analyzed, after elimination of papers written in languages other than English or not directly related to the selected topics. Conclusion:: Machine learning algorithms are computer-based statistical approaches which can be trained and are able to find common patterns from big amounts of data. The machine learning approaches can help clinicians in classifying patients according to several variables at the same time.

Extreme Gradient Boosting for Parkinson’s Disease Diagnosis from Voice Recordings

2020 ◽  
Author(s):  
Ibrahim Karabayir ◽  
Suguna Pappu ◽  
Samuel Goldman ◽  
Oguz Akbilgic
Keyword(s):  
Machine Learning ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Disease Diagnosis ◽  
Machine Learning Algorithms ◽  
Gradient Boosting ◽  
Acoustic Features ◽  
Data Set ◽  
Non Invasive ◽  
Extreme Gradient Boosting

Abstract Background : Parkinson’s Disease (PD) is a clinically diagnosed neurodegenerative disorder that affects both motor and non-motor neural circuits. Speech deterioration (hypokinetic dysarthria) is a common symptom, which often presents early in the disease course. Machine learning can help movement disorders specialists improve their diagnostic accuracy using non-invasive and inexpensive voice recordings. Method : We used “Parkinson Dataset with Replicated Acoustic Features Data Set” from the UCI-Machine Learning repository. The dataset included 45 features including sex and 44 speech test based acoustic features from 40 patients with Parkinson’s disease and 40 controls. We analyzed the data using various machine learning algorithms including tree-based ensemble approaches such as random forest and extreme gradient boosting. We also implemented a variable importance analysis to identify important variables classifying patients with PD. Results : The cohort included total of 80 subjects; 40 patients with PD (55% men) and 40 controls (67.5% men). PD patients showed at least two of the three symptoms; resting tremor, bradykinesia, or rigidity. All patients were over 50 years old and the mean age for PD subjects and controls were 69.6 (SD 7.8) and 66.4 (SD 8.4), respectively. Our final model provided an AUC of 0.940 with 95% confidence interval 0.935-0.945in 4-folds cross validation using only six acoustic features including Delta3 (Run2), Delta0 (Run 3), MFCC4 (Run 2), Delta10 (Run 2/Run 3), MFCC10 (Run 2) and Jitter_Rap (Run 1/Run 2). Conclusions : Machine learning can accurately detect Parkinson’s disease using an inexpensive and non-invasive voice recording. Such technologies can be deployed into smartphones for screening of large patient populations for Parkinson’s disease.

Parkinson’s Disease Diagnosis Using Machine Learning and Voice

2018 ◽  
Author(s):  
Timothy J. Wroge ◽  
Yasin Ozkanca ◽  
Cenk Demiroglu ◽  
Dong Si ◽  
David C. Atkins ◽  
...  
Keyword(s):  
Machine Learning ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Disease Diagnosis

A Multi-agent Feature Selection and Hybrid Classification Model for Parkinson's Disease Diagnosis

2021 ◽  
Vol 17 (2s) ◽  
pp. 1-22
Author(s):  
Mazin Abed Mohammed ◽  
Mohamed Elhoseny ◽  
Karrar Hameed Abdulkareem ◽  
Salama A. Mostafa ◽  
Mashael S. Maashi
Keyword(s):  
Machine Learning ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Feature Selection ◽  
Prediction Models ◽  
Disease Diagnosis ◽  
Classification Model ◽  
Test Results ◽  
Multi Agent ◽  
The Voice

Parkinson's disease (PD) diagnostics includes numerous analyses related to the neurological, physical, and psychical status of the patient. Medical teams analyze multiple symptoms and patient history considering verified genetic influences. The proposed method investigates the voice symptoms of this disease. The voice files are processed, and the feature extraction is conducted. Several machine learning techniques are used to recognize Parkinson's and healthy patients. This study focuses on examining PD diagnosis through voice data features. A new multi-agent feature filter (MAFT) algorithm is proposed to select the best features from the voice dataset. The MAFT algorithm is designed to select a set of features to improve the overall performance of prediction models and prevent over-fitting possibly due to extreme reduction to the features. Moreover, this algorithm aims to reduce the complexity of the prediction, accelerate the training phase, and build a robust training model. Ten different machine learning methods are then integrated with the MAFT algorithm to form a powerful voice-based PD diagnosis model. Recorded test results of the PD prediction model using the actual and filtered features yielded 86.38% and 86.67% accuracies on average, respectively. With the aid of the MAFT feature selection, the test results are improved by 3.2% considering the hybrid model (HM) and 3.1% considering the Naïve Bayesian and random forest. Subsequently, an HM, which comprises a binary convolutional neural network and three feature selection algorithms (namely, genetic algorithm, Adam optimizer, and mini-batch gradient descent), is proposed to improve the classification accuracy of the PD. The results reveal that PD achieves an overall accuracy of 93.7%. The HM is integrated with the MAFT, and the combination realizes an overall accuracy of 96.9%. These results demonstrate that the combination of the MAFT algorithm and the HM model significantly enhances the PD diagnosis outcomes.

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