A Preliminary Study on Identifying Probable Biomarker of Type 2 Diabetes using Recursive Feature Extraction

2018 ◽  
Author(s):  
Nur Nilamyani ◽  
Armin Lawi ◽  
Sri Astuti Thamrin
Keyword(s):  
Type 2 Diabetes ◽  
Feature Extraction ◽  
Preliminary Study

Role of type 2 diabetes and hemodialysis in serum adipolin concentrations: A preliminary study

2019 ◽  
Vol 23 (4) ◽  
pp. 472-478 ◽  
Author(s):  
Elham Alipoor ◽  
Mahnaz Salmani ◽  
Mehdi Yaseri ◽  
Roya Kolahdouz‐Mohammadi ◽  
Alireza Esteghamati ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Preliminary Study

Executive Functioning in Older Adult Outpatients With Type 2 Diabetes Mellitus: A Preliminary Study

2014 ◽  
Vol 37 (2) ◽  
pp. 91-107 ◽  
Author(s):  
Sara Bottiroli ◽  
Tomaso Vecchi ◽  
Francesca Campanella ◽  
Alessia Varetta ◽  
Maria Cristina Gallotti ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Executive Functioning ◽  
Older Adult ◽  
Preliminary Study

scholarly journals The Circulating Levels of CTRP1 and  CTRP5  Are Associated with Obesity Indices and  Carotid Intima-Media Thickness (cIMT) Value in Patients with Type 2 Diabetes: A Preliminary Study

2021 ◽  
Author(s):  
Ziba Majidi ◽  
Solaleh Emamgholipour ◽  
Abolfazl Omidifar ◽  
Soheil Rahmani Fard ◽  
Hossein Poustchi ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Thickness Measurement ◽  
Enzyme Linked Immunosorbent Assay ◽  
Visceral Adiposity Index ◽  
Media Thickness ◽  
Preliminary Study ◽  
Circulating Levels

Abstract Background: There is growing evidence that the C1qTNF-related protein (CTRP) family has a crucial role in the physiology and pathophysiology of metabolic disorders such as Type 2 Diabetes (T2D) and obesity. We sought to identify the association of CTRP1 and CTRP5 circulating levels with various obesity parameters such as visceral adipose tissue (VAT) thickness, visceral adiposity index (VAI), and with carotid intima-media thickness (cIMT) in patients with T2D and healthy subjects. Methods: This preliminary study consisted of men with T2D (n=42) and men without T2D (n=42). cIMT and VAT thickness measurement was performed using an Accuvix XQ ultrasound. Circulating levels of CTRP1, CTRP5, and adiponectin were measured by enzyme-linked immunosorbent assay (ELISA).Results: CTRP-1 and CTRP1/CTRP5 ratio was markedly higher in patients with T2D compared to controls (p < 0001 and p = 0004 respectively). Interestingly, binominal logistic regression revealed that a higher circulating level of CTRP1 was associated with the presence of T2D (odds ratio [OR]: 1.009 [95% CI: 1.004-1.015]; P=.001). CTRP1 circulating levels were correlated with WHR, VAT, and HOMA-IR in the whole population study. Also, we observed that the ratio of CTRP1 to CTRP5 in plasma (β = 0.648, P=0.005) and CTRP5 circulating levels (β = 0.444, P=0.049) are independently associated with cIMT value.Conclusions: Our results indicated that CTRP1 and CTRP5 concentrations were correlated with atherosclerosis in men with T2D and these adipokines might have a causal role for cardiometabolic risk in T2D.However, more studies in large sample sizes are required to clarify the role of CTRPs in T2D pathogenesis.

scholarly journals Does CD31 possess a role in patients with type 2 diabetes mellitus? a preliminary study

2021 ◽  
Vol 12 (1) ◽  
pp. 1-6
Author(s):  
Mohamed Mohey ◽  
Hanan Soliman ◽  
Ahmed Okasha
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Preliminary Study

scholarly journals The CTRP5  Circulating Levels  and the Ratio of CTRP1 to CTRP5 in Plasma are Significant Predictors for Carotid Intima-Media Thickness(cIMT) value in Patients with type 2 diabetes: A Preliminary Study

2020 ◽  
Author(s):  
Ziba Majidi ◽  
Solaleh Emamgholipour ◽  
Abolfazl Omidifar ◽  
Soheil Rahmani Fard ◽  
Hossein Poustchi ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Thickness Measurement ◽  
Enzyme Linked Immunosorbent Assay ◽  
Visceral Adiposity Index ◽  
Media Thickness ◽  
Preliminary Study ◽  
Circulating Levels

Abstract Background: There is growing evidence that the C1qTNF-related protein (CTRP) family has a crucial role in the physiology and pathophysiology of metabolic disorders such as Type 2 Diabetes (T2D) and obesity. We sought to identify the association of CTRP1 and CTRP5 circulating levels with various obesity parameters such as visceral adipose tissue (VAT) thickness, visceral adiposity index (VAI), and with carotid intima-media thickness (cIMT) in patients with T2D and healthy subjects.Methods: This preliminary study consisted of men with T2D (n=42) and men without T2D (n=42) . cIMT and VAT thickness measurement was performed using an Accuvix XQ ultrasound. Circulating levels of CTRP1, CTRP5, and adiponectin were measured by enzyme-linked immunosorbent assay (ELISA).Results: CTRP-1 and CTRP1/CTRP5 ratio were markedly higher in patients with T2D compared to controls (p < 0001 and p = 0004 respectively). Interestingly, binominal logistic regression revealed that a higher circulating level of CTRP1 was associated with the presence of T2D (odds ratio [OR]: 1.009 [95% CI: 1.004-1.015]; P=.001). CTRP1 circulating levels were correlated with WHR, VAT, and HOMA-IR in the whole population study. Also, we observed that the ratio of CTRP1 to CTRP5 in plasma (β = 0.648, P=0.005) and CTRP5 circulating levels (β = 0.444, P=0.049) are significant predictors for cIMT value.Conclusions: Our results indicated that CTRP1 and CTRP5 concentrations were correlated with atherosclerosis in men with T2D and these adipokines might have a causal role for cardiometabolic risk in T2D.However, more studies in large sample sizes are required to clarify the role of CTRPs in T2D pathogenesis.

scholarly journals Assessment of energy expenditure using doubly labeled water, physical activity by accelerometer and reported dietary intake in Japanese men with type 2 diabetes: A preliminary study

2018 ◽  
Vol 10 (2) ◽  
pp. 318-321 ◽  
Author(s):  
Eiichi Yoshimura ◽  
Kazunori Ohkawara ◽  
Kazuko Ishikawa-Takata ◽  
Satoru Yamada ◽  
Mikiya Tokui ◽  
...  
Keyword(s):  
Physical Activity ◽  
Type 2 Diabetes ◽  
Energy Expenditure ◽  
Dietary Intake ◽  
Doubly Labeled Water ◽  
Japanese Men ◽  
Preliminary Study
Sign in / Sign up

Export Citation Format

Share Document