Machine Learning for Modeling Dose-Related Organ-at-Risk Complications after Radiation Therapy

2009 ◽  
Author(s):  
Hao H. Zhang ◽  
Leyuan Shi ◽  
Robert R. Meyer ◽  
Warren D. D'Souza
Keyword(s):  
Machine Learning ◽  
At Risk ◽  
Radiation Therapy ◽  
Organ At Risk

scholarly journals Dosimetric Comparison Between Jaw Tracking and No Jaw Tracking in Intensity-Modulated Radiation Therapy

2019 ◽  
Vol 18 ◽  
pp. 153303381984106 ◽  
Author(s):  
Shengyu Yao ◽  
Yin Zhang ◽  
Tingfeng Chen ◽  
Guoqi Zhao ◽  
Zhekai Hu ◽  
...  
Keyword(s):  
At Risk ◽  
Radiation Therapy ◽  
Nasopharyngeal Carcinoma ◽  
Brain Metastasis ◽  
Intensity Modulated Radiation Therapy ◽  
Large Tumor ◽  
Intensity Modulated ◽  
Passing Rates ◽  
Passing Rate ◽  
Organ At Risk

Purpose: This article compares the dosimetric differences between jaw tracking and no jaw tracking technique in static intensity-modulated radiation therapy plans of large and small tumors. Methods: Eight plans with large tumor (nasopharyngeal carcinoma, volume range: 510.9 to 768.0 cm3) and 8 plans with small tumor (single brain metastasis, volume range: 5.3 to 9.9 cm3) treated with jaw tracking on Varian EDGE LINAC were chosen and recalculated with no jaw tracking to study the dosimetric differences. We compared the differences of organ-at-risk doses (Dmax, Dmean), monitor units, and γ passing rate of plan verification (3mm/3%, threshold 10%; 2mm/2%, threshold 10%) between the 2 techniques. Results: The organ-at-risk doses of nasopharyngeal carcinoma cases having jaw tracking are all less than those with no jaw tracking. The Dmax and Dmean of organ-at-risks reduced 0.61% to 17.65% and 2.17% to 19.32%, P < .05, respectively. In cases with single brain metastasis, the organ-at-risk doses with jaw tracking were also lower than no jaw tracking. The Dmax and Dmean of organ-at-risk doses reduced 0.84% to 1.52% and 0.90% to 1.86%, P < .05, respectively. The monitor units for the large tumor and small tumor were increased by 2.41% and 1.1%, respectively. The γ passing rates (3mm/3%, th10%; 2mm/2%, th10%) of nasopharyngeal carcinoma plans are 99.89% ± 0.06% (jaw tracking) versus 99.56% ± 0.19% (no jaw tracking; P = .127); 97.15% ± 0.98% (jaw tracking) versus 91.90% ± 1.40% (no jaw tracking; P = .000), and the γ passing rates (3mm/3%, th10%; 2mm/2%, th10%) of brain metastasis plans are 99.97% ± 0.05% (jaw tracking) versus 99.44% ± 1.24% (no jaw tracking; P = .251), 98.65% ± 1.27% (jaw tracking) versus 93.35% ± 2.72% (no jaw tracking; P = .000). Conclusion: Jaw tracking can reduce the dose of organ-at-risks compared to no jaw tracking, and the effect is more significant for plans with large tumor. The γ passing rate of plans with jaw tracking is also higher than the plans with no jaw tracking. Although the monitor units in plans of jaw tracking will increase slightly, it is recommended to use jaw tracking in static intensity-modulated radiation therapy both in large and in small tumors.

Impact of Multi-Institutional Prospective Peer Review on Target and Organ-at-Risk Delineation in Radiation Therapy

2019 ◽  
Vol 9 (2) ◽  
pp. e228-e235 ◽  
Author(s):  
Adam C. Riegel ◽  
Marissa Vaccarelli ◽  
Brett W. Cox ◽  
Henry Chou ◽  
Yijian Cao ◽  
...  
Keyword(s):  
At Risk ◽  
Radiation Therapy ◽  
Peer Review ◽  
Organ At Risk

Impact of lung tumor motion on dose delivered to organ at risk in lung stereotactic body radiation therapy

2020 ◽  
Vol 9 (3-4) ◽  
pp. 191-198
Author(s):  
Milovan Savanovic ◽  
Bojan Strbac ◽  
Drazan Jaros ◽  
Dejan Cazic ◽  
Jean Noel Foulquier
Keyword(s):  
At Risk ◽  
Radiation Therapy ◽  
Stereotactic Body Radiation Therapy ◽  
Lung Tumor ◽  
Tumor Motion ◽  
Stereotactic Body Radiation ◽  
Organ At Risk

scholarly journals Adrenal Stereotactic Body Radiation Therapy: The Effects of a Full and Empty Stomach on Radiation Dose to Organs at Risk

2021 ◽  
Author(s):  
Osamu Tanaka ◽  
Takuya Taniguchi ◽  
Kousei Ono ◽  
Shuto Nakaya ◽  
Takuji Kiryu ◽  
...  
Keyword(s):  
At Risk ◽  
Radiation Therapy ◽  
Stereotactic Body Radiation Therapy ◽  
Organs At Risk ◽  
Left Kidney ◽  
Empty Stomach ◽  
Full Group ◽  
Left Adrenal Gland ◽  
Stereotactic Body Radiation ◽  
Organ At Risk

Abstract BackgroundStereotactic Body Radiation Therapy (SBRT) has been reported to be curative in the treatment of oligometastases to the adrenal glands. However, the adrenals are surrounded by radiation-sensitive organs. We performed an Organ at Risk (OAR) analysis for SBRT to the left adrenal gland based on gastric state.Patients and MethodsTwenty random stomachs were divided into “empty” or “full” groups of 10 each based on size. The PTV dose was 54 Gy/6 fx and D 95 coverage of PTV(CTV) (the dose to 95% of the PTV volume). ResultsThe gastric OAR dose in the empty group was significantly lower than the full group. The OAR dose to the left kidney in the empty group was significantly higher than in the full group.ConclusionThe smaller the stomach size, the lower the dose to the stomach. It is therefore better to perform SBRT on patients with an empty stomach.

The Dosimetric Impact of Interfractional Organ-at-Risk Movement During Liver Stereotactic Body Radiation Therapy

2019 ◽  
Vol 9 (6) ◽  
pp. e549-e558 ◽  
Author(s):  
Ryan K. Schmid ◽  
An Tai ◽  
Slade Klawikowski ◽  
Michael Straza ◽  
Khalid Ramahi ◽  
...  
Keyword(s):  
At Risk ◽  
Radiation Therapy ◽  
Stereotactic Body Radiation Therapy ◽  
Stereotactic Body Radiation ◽  
Organ At Risk

scholarly journals Dosimetric analysis of varying cord planning organ at risk volume in spine stereotactic body radiation therapy

2016 ◽  
Vol 1 (1) ◽  
pp. 76-81 ◽  
Author(s):  
Dawn Owen ◽  
Charles S. Mayo ◽  
Limin Song ◽  
Kamran Ahmed ◽  
Nadia Laack ◽  
...  
Keyword(s):  
At Risk ◽  
Radiation Therapy ◽  
Stereotactic Body Radiation Therapy ◽  
Stereotactic Body Radiation ◽  
Organ At Risk ◽  
Dosimetric Analysis
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