Maternal caries experience influences offspring’s early childhood caries—a birth cohort study

Aims: This study investigated caries predictors in 378 children remaining from a birth cohort of 1,052 at 7 y and compared the efficacy of home visits (HVs) and telephone contacts (TCs) for early childhood caries (ECC) prevention. Methods: The HVs or TCs were made at ages 6, 12, 18, 30, and 42 mo with annual dental clinic examinations at ages 2 to 7 y. At every visit, the parents completed validated questionnaires regarding the children’s family, medical, dental, and dietary histories. Results: The caries prevalence increased from 2% and 6% at ages 2 and 3 y to 15%, 33%, 42%, and 52% at ages 4 to 7 y. The mean caries experience (decayed, missing, and teeth extracted due to caries) of the total cohort increased from 0.1 ± 0.5 at age 2 y to 0.2 ± 1.1 at 3 y, 0.5 ± 1.6 at 4 y, 1.1 ± 2.4 at 5 y, 1.6 ± 2.6 at 6 y, and 2.0 ± 2.7 at 7 y. The prevalence of mutans streptococci (MS) in the total cohort at years 2 to 7 was 22%, 36%, 42%, 42%, 39%, and 44%, respectively. MS was strongly correlated with caries prevalence for all years (all P < 0.001). Statistical modeling employing the generalized estimating equations identified caries predictors as holding a Health Care Card (low socioeconomic status) ( P = 0.009; odds ratio [OR] = 2.05; confidence interval [CI]: 1.20–3.52), developmental defects of enamel (DDEs) ( P < 0.001; OR = 1.09; CI: 1.05–1.14), and MS counts ≤105/mL ( P = 0.001; OR = 1.63; CI: 1.24–2.14). By contrast, HVs were more protective than TCs for caries ( P = 0.008; OR = 0.42; CI: 0.22–0.80). Conclusions: This study provides prospective, clinical evidence that MS, DDEs, and low socioeconomic status are strongly correlated with early childhood caries and that HVs are more efficacious than TCs in ECC prevention. Knowledge Transfer Statement: This 7-y birth cohort study provides longitudinal clinical evidence that mutans streptococci, developmental defects of enamel, and low socioeconomic status are key risk indicators of early childhood caries.

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Prenatal Bisphenol A exposure and early childhood behavior and cognitive function: a Chinese birth cohort study

Neuroendocrinology ◽

10.1159/000516881 ◽

2021 ◽

Author(s):

Zhaohui Huang ◽

Weinan Fu ◽

Lianjie Dou ◽

Huihui Bao ◽

Wanke Wu ◽

...

Keyword(s):

Early Childhood ◽

Cohort Study ◽

Cognitive Function ◽

Bisphenol A ◽

Birth Cohort ◽

Birth Cohort Study ◽

Childhood Behavior ◽

Early Childhood Behavior

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The link between sleep problems in infancy and early childhood and attention problems at 5 and 14years: Evidence from a birth cohort study

Early Human Development ◽

10.1016/j.earlhumdev.2010.05.020 ◽

2010 ◽

Vol 86 (7) ◽

pp. 419-424 ◽

Cited By ~ 44

Author(s):

Frances V. O'Callaghan ◽

Abdullah Al Mamun ◽

Michael O'Callaghan ◽

Alexandra Clavarino ◽

Gail M. Williams ◽

...

Keyword(s):

Early Childhood ◽

Cohort Study ◽

Birth Cohort ◽

Sleep Problems ◽

Attention Problems ◽

Birth Cohort Study ◽

Infancy And Early Childhood

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Staphylococcus aureus sensitization and allergic disease in early childhood: Population-based birth cohort study

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2006.12.639 ◽

2007 ◽

Vol 119 (4) ◽

pp. 930-936 ◽

Cited By ~ 33

Author(s):

Aida Semic-Jusufagic ◽

Claus Bachert ◽

Philippe Gevaert ◽

Gabriele Holtappels ◽

Lesley Lowe ◽

...

Keyword(s):

Staphylococcus Aureus ◽

Early Childhood ◽

Cohort Study ◽

Birth Cohort ◽

Allergic Disease ◽

Population Based ◽

Birth Cohort Study ◽

Childhood Population

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Association of Feeding Methods and Streptococcus mutans Count with Early Childhood Caries: A Cross-sectional Study

International Journal of Clinical Pediatric Dentistry ◽

10.5005/jp-journals-10005-1420 ◽

2017 ◽

Vol 10 (2) ◽

pp. 119-125 ◽

Cited By ~ 2

Author(s):

Manjunath P Puranik ◽

Deepa Bullappa ◽

KR Sowmya ◽

T Nagarathnamma

Keyword(s):

Early Childhood ◽

Streptococcus Mutans ◽

Early Childhood Caries ◽

Cross Sectional Study ◽

Caries Experience ◽

Sectional Study ◽

Cross Sectional ◽

Mothers And Children ◽

Feeding Methods ◽

Childhood Caries

ABSTRACT Introduction Early childhood caries (ECC) is a virulent form of dental caries that can destroy the primary dentition of toddlers and preschool children. The aim was to determine the relationship of feeding methods and oral Streptococcus mutans count in 3- to 5-year-old children with ECC. Materials and methods A cross-sectional study was conducted in children aged 3 to 5 years. Participating mothers were interviewed regarding child's demographic profile, educational level and socioeconomic status of parents, past medical and dental history of the mother and child, child's feeding habits, and dietary habits and oral hygiene practices of mother and child. Clinical examination for dental caries was done using the World Health Organization criteria (1997). Salivary samples of mother–child pair were collected to determine the pH, flow rate, and S. mutans count. Statistical tests, such as Student's t-test, analysis of variance, and Pearson's correlation were applied. Results Out of 150 mother–child pair, statistically significant difference in the caries experience was found between mothers and children with high and low S. mutans count. Moderate but statistically significant negative correlation was found between mean decayed, missing, and filled teeth of mothers and mean decayed, extracted and filled teeth (deft) of children with high S. mutans count. Regarding deft, there was no statistically significant difference between children who were exclusively breast fed (7.85 ± 2.94), exclusively bottle-fed (8.67 ± 3.98), and both breast and bottle-fed (7.77 ± 2.91). Conclusion The mean caries experience of mothers and children was 2.66 ± 2.01 and 7.82 ± 2.94 respectively, with decayed component being maximum. Moderate and significant correlation (r = 0.5) was found between S. mutans of mothers and children in saliva. Significant negative correlation was found between mothers and children with high S. mutans count (r = –0.0284; p = 0.046). How to cite this article Bullappa D, Puranik MP, Sowmya KR, Nagarathnamma T. Association of Feeding Methods and Streptococcus mutans Count with Early Childhood Caries: A Cross-sectional Study. Int J Clin Pediatr Dent 2017;10(2):119-125.

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Early life and socio-economic determinants of dietary trajectories in infancy and early childhood – results from the HSHK birth cohort study

Nutrition Journal ◽

10.1186/s12937-021-00731-3 ◽

2021 ◽

Vol 20 (1) ◽

Author(s):

Narendar Manohar ◽

Andrew Hayen ◽

Loc Do ◽

Jane Scott ◽

Sameer Bhole ◽

...

Keyword(s):

Early Childhood ◽

Cohort Study ◽

Birth Cohort ◽

Early Life ◽

Maternal Education ◽

Multinomial Logistic Regression ◽

Preschool Age ◽

Breastfeeding Duration ◽

Birth Cohort Study ◽

Infancy And Early Childhood

Abstract Background Early childhood is a period when dietary behaviours are established. This study aimed to examine the longitudinal intake of core and discretionary foods and identify early life and socio-economic factors influencing those intakes. Methods Mother-infant dyads (n = 934) from the Healthy Smiles Healthy Kids study, an ongoing birth cohort study, were interviewed. The information on ‘weekly frequency of core and discretionary foods intake’ using a food frequency questionnaire was collected at 4 months, 8 months, 1 year, 2 years and 3 years age points. Group-based trajectory modelling analyses were performed to identify diet trajectories for ‘core’ and ‘discretionary’ foods respectively. A multinomial logistic regression was performed to identify the maternal and child-related predictors of resulting trajectories. Results The intake of core and discretionary foods each showed distinct quadratic (n = 3) trajectories with age. Overall, core foods intake increased rapidly in the first year of life, followed by a decline after age two, whereas discretionary foods intake increased steadily across the five age points. Multiparity (Relative Risk (RR): 0.46, 95%CI: 0.27–0.77), non-English speaking ethnicity of mother (RR: 0.66, 95%CI: 0.47–0.91) and having a single mother (RR: 0.40, 95%CI: 0.18–0.85) were associated with low trajectories of core foods intake whereas older maternal age (RR: 1.05, 95%CI: 1.01–1.08) and longer breastfeeding duration (RR: 1.02, 95%CI: 1.00–1.03) were associated with higher trajectories of core foods intake. Also, multiparity (RR 2.63, 95%CI: 1.47–4.70), low maternal education (RR 3.01, 95%CI: 1.61–5.65), and socio-economic disadvantage (RR 2.69, 95%CI: 1.31–5.55) were associated with high trajectories of discretionary foods intake. Conversely, longer duration of breastfeeding (RR 0.99, 95%CI: 0.97–0.99), and timely introduction of complementary foods (RR 0.30, 95%CI: 0.15–0.61) had a protective effect against high discretionary foods consumption in infancy and early childhood. Conclusion Children’s frequency of discretionary foods intake increases markedly as they transition from infancy to preschool age, and the trajectories of intake established during early childhood are strongly influenced by socio-demographic factors and infant feeding choices. Hence, there is a need for targeted strategies to improve nutrition in early childhood and ultimately prevent the incidence of chronic diseases in children.

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