What is the impact of bisphosphonate therapy upon dental implant survival? A systematic review and meta-analysis

2014 ◽  
Vol 27 (2) ◽  
pp. e38-e46 ◽  
Author(s):  
Javier Ata-Ali ◽  
Fadi Ata-Ali ◽  
David Peñarrocha-Oltra ◽  
Pablo Galindo-Moreno
Keyword(s):  
Systematic Review ◽  
Dental Implant ◽  
Meta Analysis ◽  
Bisphosphonate Therapy ◽  
Implant Survival ◽  
The Impact

scholarly journals Dental implants in immunocompromised patients: a systematic review and meta-analysis

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Fabian Duttenhoefer ◽  
Marc Anton Fuessinger ◽  
Yasmin Beckmann ◽  
Rainer Schmelzeisen ◽  
Knut A. Groetz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dental Implant ◽  
Meta Analysis ◽  
Cochrane Collaboration ◽  
Implant Failure ◽  
Immunocompromised Patients ◽  
Implant Survival ◽  
Life Saving ◽  
Impaired Health ◽  
The Cochrane Collaboration

Abstract Objective Impaired health conditions and related lack of adequate host healing are among the most important conditions that account for dental implant failure. Today clinicians face an increasing number of immunocompromised patients requesting implant-based rehabilitation. To provide clinical evidence for prospective decision-making, the aim of this systematic review and meta-analysis was to analyse the influence of immunodeficiency on dental implant survival. Methods The study was conducted according to the PRISMA Statement and the principles of the Cochrane Collaboration. MEDLINE and Web of Science were searched. Results were calculated by the pooled incidence of implant loss. Reported odds ratios (OR) from fully adjusted models were preferred. Distinct risk estimates were synthesised with 95% confidence intervals. Results A total of 62 publications including 1751 endosseous implants placed in immunocompromised patients were included. For the follow-up of 24 months and longer, the mean survival rate of implants in patients with HIV was 93.1%, chemotherapy was 98.8%, autoimmune disease was 88.75%, after organ transplantation was 100%. Crohn’s disease showed a significant effect on early implant failure and resulted in increased, however not significant, implant loss. Conclusion No significant effect of immunocompromised conditions on implant survival was detectable. Implant-based therapy in immunocompromised patients should not aggravate the general morbidity and must not interfere in life-saving therapies. A careful risk stratification prior implant therapy is fundamental. To further decipher the role of immunosuppression on dental implantology, more data from controlled and randomised studies are needed.

scholarly journals Dental Implant Survival in Vascularized Bone Flaps: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 146 (3) ◽  
pp. 637-648
Author(s):  
Hina Panchal ◽  
Meghana G. Shamsunder ◽  
Ivana Petrovic ◽  
Evan B. Rosen ◽  
Robert J. Allen ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dental Implant ◽  
Meta Analysis ◽  
Implant Survival ◽  
Vascularized Bone

scholarly journals Effect of advanced age and/or systemic medical conditions on dental implant survival: A systematic review and meta‐analysis

2018 ◽  
Vol 29 (S16) ◽  
pp. 311-330 ◽  
Author(s):  
Martin Schimmel ◽  
Murali Srinivasan ◽  
Gerald McKenna ◽  
Frauke Müller
Keyword(s):  
Systematic Review ◽  
Dental Implant ◽  
Meta Analysis ◽  
Advanced Age ◽  
Medical Conditions ◽  
Implant Survival

scholarly journals Can Genetic Factors Compromise the Success of Dental Implants? A Systematic Review and Meta-Analysis

2018 ◽  
Author(s):  
Joel Ferreira Santiago Junior ◽  
Claudia Cristina Biguetti ◽  
Mariza Akemi Matsumoto ◽  
Guilherme Abu Halawa Kudo ◽  
Raquel Barroso Parra da Silva ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dental Implants ◽  
Dental Implant ◽  
Genetic Factors ◽  
Association Studies ◽  
Meta Analysis ◽  
Implant Failure ◽  
High Survival ◽  
Dna Variations ◽  
The Impact

Dental implants provide a predictable treatment option for partial and complete edentulism via the placement of fixed permanent artificial root to support prosthetic dental crowns. Despite the high survival rates, long-term implant failures are still reported leading to implant removal and additional financial and health burdens. While extrinsic factors that improve survival rate of implants have been well explored, the impact of genetic factors on this matter is poorly understood. A systematic review and meta-analysis study was conducted to determine whether genetic factors contribute to increase the risk of dental implant failure. A comprehensive search for peer-reviewed articles on dental implants and genetics was performed using various literature database libraries. The study design was conducted according to PRISMA guidelines, and the obtained records were registered in PROSPERO database. According to the exclusion/inclusion criteria, 11 studies were eligible for this study out of 808 articles. The meta-analysis of the combined association studies of DNA variations and dental implants did not indicate an increase risk for implant failure due to DNA variations in IL-1B, IL-10 and TNF-α. This study emphasizes the need for larger randomized controlled clinical trails to inform clinicians and patients about the role of genetic factors on dental implant survival and success rate in healthy and compromised patients.

scholarly journals Can Genetic Factors Compromise the Success of Dental Implants? A Systematic Review and Meta-Analysis

Genes ◽  
2018 ◽  
Vol 9 (9) ◽  
pp. 444 ◽  
Author(s):  
Joel Santiago Junior ◽  
Claudia Biguetti ◽  
Mariza Matsumoto ◽  
Guilherme Abu Halawa Kudo ◽  
Raquel Parra da Silva ◽  
...  
Keyword(s):  
Systematic Review ◽  
Success Rate ◽  
Dental Implants ◽  
Dental Implant ◽  
Systematic Reviews ◽  
Genetic Factors ◽  
Meta Analysis ◽  
Increased Risk ◽  
Dna Variations ◽  
The Impact

Dental implants provide a predictable treatment option for partial and complete edentulism via the placement of a fixed permanent artificial root to support prosthetic dental crowns. Despite the high survival rates, long-term dental implant failures are still reported, leading to implant removals and additional financial and health burdens. While extrinsic factors that improve the success rate of implants have been well explored, the impact of genetic factors on this matter is poorly understood. A systematic review and meta-analysis study was conducted to determine whether genetic factors contribute to an increased risk of dental implant failures. A comprehensive search for peer-reviewed articles on dental implants and genetic factors was performed using various literature database libraries. The study design was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, and the obtained records were registered in the International Prospective Register of Systematic Reviews (PROSPERO) database. According to the exclusion/inclusion criteria, 13 studies were eligible for this study out of 809 articles. The meta-analysis of the combined association studies of DNA variations and dental implants did not indicate an increased risk for implant failure due to DNA variations in IL-1B, IL-10 and TNF-α. This study emphasizes the need for larger randomized controlled clinical trials to inform clinicians and patients about the role of genetic factors on dental implant survival and the success rate in healthy and compromised patients.

Sign in / Sign up

Export Citation Format

Share Document