Time interval between rectal cancer resection and reintervention for anastomotic leakage and the impact of a defunctioning stoma: A Dutch population‐based study

2021 ◽  
Author(s):  
Anne‐Loes K. Warps ◽  
Rob A. E. M. Tollenaar ◽  
Pieter J. Tanis ◽  
Jan Willem T. Dekker ◽  
Keyword(s):  
Rectal Cancer ◽  
Anastomotic Leakage ◽  
Population Based ◽  
Time Interval ◽  
Dutch Population ◽  
Population Based Study ◽  
Defunctioning Stoma ◽  
Cancer Resection ◽  
Rectal Cancer Resection ◽  
The Impact

scholarly journals Rectal cancer resection and circumferential margin rates in Canada: a population-based study

2014 ◽  
Vol 22 (1) ◽  
pp. 60 ◽  
Author(s):  
K. DeCaria ◽  
R. Rahal ◽  
J. Niu ◽  
G. Lockwood ◽  
H. Bryant
Keyword(s):  
Rectal Cancer ◽  
Population Based ◽  
Circumferential Margin ◽  
Population Based Study ◽  
Cancer Resection ◽  
Rectal Cancer Resection

scholarly journals Stoma reversal after intended restorative rectal cancer resection in Denmark: nationwide population‐based study

BJS Open ◽  
2020 ◽  
Vol 4 (6) ◽  
pp. 1162-1171
Author(s):  
J. B. Jørgensen ◽  
R. Erichsen ◽  
B. G. Pedersen ◽  
S. Laurberg ◽  
L. H. Iversen
Keyword(s):  
Rectal Cancer ◽  
Population Based ◽  
Population Based Study ◽  
Cancer Resection ◽  
Stoma Reversal ◽  
Rectal Cancer Resection

Minimally invasive approaches to the management of anastomotic leakage following restorative rectal cancer resection

2019 ◽  
Vol 21 (12) ◽  
pp. 1364-1371 ◽  
Author(s):  
B. Creavin ◽  
É. J. Ryan ◽  
M. E. Kelly ◽  
A. Moynihan ◽  
C. E. Redmond ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Minimally Invasive ◽  
Anastomotic Leakage ◽  
Cancer Resection ◽  
Rectal Cancer Resection

scholarly journals LARS is Associated with Lower Anastomoses, but not with the Transanal Approach in Patients Undergoing Rectal Cancer Resection

2020 ◽  
Author(s):  
Alexandra Filips ◽  
Tobias Haltmeier ◽  
Andreas Kohler ◽  
Daniel Candinas ◽  
Lukas Brügger ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Anterior Resection ◽  
Functional Outcomes ◽  
Low Anterior Resection ◽  
Regression Coefficient ◽  
Anal Verge ◽  
Transanal Approach ◽  
Cancer Resection ◽  
Rectal Cancer Resection ◽  
The Impact

Abstract Background Low anterior resection syndrome (LARS) is a defecation disorder that frequently occurs after a low anterior resection (LAR) with a total mesorectal excision (TME). The transanal (ta) TME for low rectal pathologies could potentially overcome some of the difficulties encountered with the abdominal approach in a narrow pelvis. However, the impact of the transanal approach on functional outcomes remains unknown. Here, we investigated the effect of the taTME approach on functional outcomes by comparing LARS scores between the LAR and taTME approaches in patients with colorectal cancer. Methods We conducted a retrospective cohort study including 80 patients (n = 40 LAR-TME, n = 40 taTME) with rectal adenocarcinoma. We reviewed medical charts to obtain LARS scores 6 months after the rectal resection or a reversal of the protective ileostomy. Results At the 6-month follow-up, 80% of patients exhibited LARS symptoms (44% minor LARS and 36% major LARS). LARS scores were not significantly associated with the T-stage, N-stage, or neo-adjuvant radiotherapy. The mean distance of the anastomosis from the anal verge was 4.0 ± 2.0 cm. The taTME group had significantly lower anastomoses compared with the LAR-TME group (median 4.0 cm [IQR1.8] vs. median 5.0 cm [IQR 2.0], p < 0.001). Univariable analysis revealed significantly higher LARS scores in the taTME group compared with the LAR-TME group (median LARS scores: 29 vs. 25, p = 0.040). However, multivariable regression analysis, adjusting for neo-adjuvant treatment, anastomosis distance from the anal verge, anastomotic leak rate, and body mass index, revealed no significant effect of taTME on the LARS score (adjusted regression coefficient:  − 2.147, 95%CI:  − 2.130 to 6.169, p = 0.359). We also found a significant correlation between LARS scores and the distance of the anastomosis from the anal verge (regression coefficient:  − 1.145, 95%CI:  − 2.149 to  − 1.141, p = 0.026). Conclusion Fifty percentage of patients in this cohort exhibited some LARS symptoms after a mid- or low-rectal cancer resection. As previously described, LARS scores were negatively correlated with the distance of the anastomosis from the anal verge. TaTME was after adjustment for the height of the anastomosis not associated with higher LARS at 6 months when compared with LAR-TME.

Impact of anastomotic leakage on oncological outcome after rectal cancer resection

2007 ◽  
Vol 94 (12) ◽  
pp. 1548-1554 ◽  
Author(s):  
H. Ptok ◽  
F. Marusch ◽  
F. Meyer ◽  
D. Schubert ◽  
I. Gastinger ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Anastomotic Leakage ◽  
Oncological Outcome ◽  
Cancer Resection ◽  
Rectal Cancer Resection

Intrathoracic Anastomotic Leakage and Mortality After Esophageal Cancer Resection: A Population-Based Study

2011 ◽  
Vol 19 (1) ◽  
pp. 99-103 ◽  
Author(s):  
Martin Rutegård ◽  
Pernilla Lagergren ◽  
Ioannis Rouvelas ◽  
Jesper Lagergren
Keyword(s):  
Esophageal Cancer ◽  
Anastomotic Leakage ◽  
Population Based ◽  
Population Based Study ◽  
Cancer Resection
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