scholarly journals Morphological and histological investigation of the conduction system in the equine atrial muscle sleeve of pulmonary veins

2021 ◽  
Vol 53 (S55) ◽  
pp. 34-34
Keyword(s):  
Pulmonary Veins ◽  
Conduction System ◽  
Histological Investigation ◽  
Atrial Muscle

scholarly journals Long-standing Persistent Atrial Fibrillation Ablation: the Role of the Inter- and Intra-atrial Bundles

2020 ◽  
Vol 33 (2) ◽  
pp. 73-81
Author(s):  
Russell Mitchell ◽  
Cesar Augusto Bonilla Isaza
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Clinical Outcomes ◽  
Pulmonary Veins ◽  
Persistent Atrial Fibrillation ◽  
Conduction System ◽  
Atrial Fibrillation Ablation ◽  
Anatomical Location

Catheter ablation has become the mainstream treatment of atrial fibrillation, but still remains a challenge in those patient with persistent and long standing persistent atrial fibrillation. In addition of isolation of the pulmonary veins, any other areas that can trigger or perpetuate atrial fibrillation need to be isolated. Current technologies may allow to effectively deliver permanently lasting lesions, and therefore improve clinical outcomes after ablation. The specialized conduction system including the Bachmann and septopulmonary bundles, are important substrate targets for the management of atrial fibrillation. The anatomical location of these fibers, and the corresponding approach for ablation are described in this case.

scholarly journals Effect of Antazoline on Electrophysiological Properties of Atrial Muscle and Conduction System of the Heart

2018 ◽  
Vol 32 (2) ◽  
pp. 169-173 ◽  
Author(s):  
Bartłomiej Jacek Bińkowski ◽  
Marcin Makowski ◽  
Paweł Kubiński ◽  
Andrzej Lubiński
Keyword(s):  
Conduction System ◽  
Electrophysiological Properties ◽  
Atrial Muscle

scholarly journals 2880Impact of antazoline on electrophysiologic properties of atrial muscle and conduction system of the heart

2017 ◽  
Vol 38 (suppl_1) ◽  
Author(s):  
B. Binkowski ◽  
M. Makowski ◽  
P. Kubinski ◽  
A. Lubinski
Keyword(s):  
Conduction System ◽  
Atrial Muscle

Molecular and Microscopic Analysis of Altered Gene Expression in Transgenic and Gene Targeted Mice

1996 ◽  
Vol 54 ◽  
pp. 12-13
Author(s):  
W. K. Jones ◽  
J. Robbins
Keyword(s):  
Gene Expression ◽  
Pulmonary Veins ◽  
Microscopic Analysis ◽  
Mouse Tissue ◽  
Adult Heart ◽  
Heavy Chains ◽  
Altered Gene Expression ◽  
Altered Gene ◽  
Pulmonary Myocardium

Two myosin heavy chains (MyHC) are expressed in the mammalian heart and are differentially regulated during development. In the mouse, the α-MyHC is expressed constitutively in the atrium. At birth, the β-MyHC is downregulated and replaced by the α-MyHC, which is the sole cardiac MyHC isoform in the adult heart. We have employed transgenic and gene-targeting methodologies to study the regulation of cardiac MyHC gene expression and the functional and developmental consequences of altered α-MyHC expression in the mouse.We previously characterized an α-MyHC promoter capable of driving tissue-specific and developmentally correct expression of a CAT (chloramphenicol acetyltransferase) marker in the mouse. Tissue surveys detected a small amount of CAT activity in the lung (Fig. 1a). The results of in situ hybridization analyses indicated that the pattern of CAT transcript in the adult heart (Fig. 1b, top panel) is the same as that of α-MyHC (Fig. 1b, lower panel). The α-MyHC gene is expressed in a layer of cardiac muscle (pulmonary myocardium) associated with the pulmonary veins (Fig. 1c). These studies extend our understanding of α-MyHC expression and delimit a third cardiac compartment.

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