scholarly journals Microenvironmental markers are correlated with lymph node metastasis in invasive submucosal colorectal cancer

2021 ◽  
Author(s):  
Tamotsu Sugai ◽  
Noriyuki Yamada ◽  
Mitsumasa Osakabe ◽  
Mai Hashimoto ◽  
Noriyuki Uesugi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Node Metastasis ◽  
Submucosal Colorectal Cancer

A Novel Mirna Signature for the Detection of Lymph Node Metastasis in Submucosal Colorectal Cancer Patients

2017 ◽  
Vol 152 (5) ◽  
pp. S1019-S1020
Author(s):  
Tsuyoshi Ozawa ◽  
Feng Gao ◽  
Hiroaki Nozawa ◽  
Keisuke Hata ◽  
Hiroshi Nagata ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cancer Patients ◽  
Mirna Signature ◽  
Node Metastasis ◽  
Novel Mirna ◽  
Colorectal Cancer Patients ◽  
Submucosal Colorectal Cancer

Cathepsin D expression as a possible predictor of lymph node metastasis in submucosal colorectal cancer

2001 ◽  
Vol 37 (2) ◽  
pp. 180-188 ◽  
Author(s):  
H Oh-e ◽  
S Tanaka ◽  
Y Kitadai ◽  
F Shimamoto ◽  
M Yoshihara ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cathepsin D ◽  
Node Metastasis ◽  
Submucosal Colorectal Cancer

Angiogenesis at the site of deepest penetration predicts lymph node metastasis of submucosal colorectal cancer

2000 ◽  
Vol 118 (4) ◽  
pp. A514
Author(s):  
Shinji Tanaka ◽  
Hirotoki Oh-e ◽  
Ken Haruma ◽  
Shiro Oka ◽  
Yasuhiko Kitadai ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Node Metastasis ◽  
Submucosal Colorectal Cancer

Angiogenesis at the site of deepest penetration predicts lymph node metastasis of submucosal colorectal cancer

2001 ◽  
Vol 44 (8) ◽  
pp. 1129-1136 ◽  
Author(s):  
Hirotoki Oh-e ◽  
Shinji Tanaka ◽  
Yasuhiko Kitadai ◽  
Fumio Shimamoto ◽  
Masaharu Yoshihara ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Node Metastasis ◽  
Submucosal Colorectal Cancer

scholarly journals Predictive microRNAs for lymph node metastasis in endoscopically resectable submucosal colorectal cancer

Oncotarget ◽  
2016 ◽  
Vol 7 (22) ◽  
pp. 32902-32915 ◽  
Author(s):  
Chan Kwon Jung ◽  
Seung-Hyun Jung ◽  
Seon-Hee Yim ◽  
Ji-Han Jung ◽  
Hyun Joo Choi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Node Metastasis ◽  
Submucosal Colorectal Cancer

scholarly journals Increased Expression of VANGL1 is Predictive of Lymph Node Metastasis in Colorectal Cancer: Results from a 20-Gene Expression Signature

2021 ◽  
Vol 11 (2) ◽  
pp. 126
Author(s):  
Noshad Peyravian ◽  
Stefania Nobili ◽  
Zahra Pezeshkian ◽  
Meysam Olfatifar ◽  
Afshin Moradi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Candidate Genes ◽  
Case Series ◽  
Gene Expression Signature ◽  
Gene Panel ◽  
Expression Levels ◽  
Node Metastasis

This study aimed at building a prognostic signature based on a candidate gene panel whose expression may be associated with lymph node metastasis (LNM), thus potentially able to predict colorectal cancer (CRC) progression and patient survival. The mRNA expression levels of 20 candidate genes were evaluated by RT-qPCR in cancer and normal mucosa formalin-fixed paraffin-embedded (FFPE) tissues of CRC patients. Receiver operating characteristic curves were used to evaluate the prognosis performance of our model by calculating the area under the curve (AUC) values corresponding to stage and metastasis. A total of 100 FFPE primary tumor tissues from stage I–IV CRC patients were collected and analyzed. Among the 20 candidate genes we studied, only the expression levels of VANGL1 significantly varied between patients with and without LNMs (p = 0.02). Additionally, the AUC value of the 20-gene panel was found to have the highest predictive performance (i.e., AUC = 79.84%) for LNMs compared with that of two subpanels including 5 and 10 genes. According to our results, VANGL1 gene expression levels are able to estimate LNMs in different stages of CRC. After a proper validation in a wider case series, the evaluation of VANGL1 gene expression and that of the 20-gene panel signature could help in the future in the prediction of CRC progression.

16. Apical lymph node metastasis and survival in resected colorectal cancer

Pathology ◽  
2015 ◽  
Vol 47 ◽  
pp. S105
Author(s):  
Nav Gill ◽  
Christopher W. Toon ◽  
Nicole Watson ◽  
Anthony J. Gill
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Node Metastasis
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