Cloacal exstrophy and related abdominal wall defects in Manitoba: Incidence and demographic factors

2008 ◽  
Vol 27 (3) ◽  
pp. 241-251 ◽  
Author(s):  
Jane A. Evans ◽  
Kathleen D. Darvill ◽  
Cynthia Trevenen ◽  
Cheryl Rockman-Greenberg
Author(s):  
Andrew H. Shitta ◽  
Mercy W. Isichei ◽  
Ezekiel D. Dung ◽  
Solomon D. Peter ◽  
Michael B. Ode ◽  
...  

Background: Congenital anterior abdominal wall defects (AAWD) is a spectrum of abdominal wall defects that includes omphalocele, gastroschisis, bladder exstrophy, cloacal exstrophy, prune belly syndrome and pentalogy of Cantrell. Early Prenatal diagnosis of AAWD provides opportunity for abnormal karyotypes screening and planned delivery in a specialized centre. Ultrasound can detect these defects during pregnancy. This study aims to evaluate the detection rate of AAWD during routine obstetric ultrasonography in our region.Methods: A retrospective study of all patients that presented with AAWD to our centre from January 2008 to July 2020. Data included patient’s age, sex, birth weight, diagnosis, resuscitation time, outcome, maternal age, parity and antenatal ultrasound scan (USS) records. Antenatal USS before 12 weeks only, were excluded. Data analysed using excel.Results: Of the 140 with AAWD, 84.29% had omphalocele, 10% gastroschisis, 2.14% prune belly syndrome and 0.71% each with bladder exstrophy, cloacal exstrophy and pentalogy of Cantrell. There were 123 booked pregnancies. Majority (112) had antenatal care elsewhere while 11 attended our Centre. Ultrasonography of 108 pregnancies scanned at12 weeks or beyond, had 4 confirmed prenatal diagnosis of AAWD. All done in our centre. Mean gestational age at diagnosis was 24weeks. Outcome was rupture1 (25%) and 25% mortality (prenatally diagnosed) and 51.92% mortality for patients with missed diagnosis.Conclusions: Our obstetric ultrasound detection rate of AAWD is very low. There is a need for improvement in training to improve perinatal care of these defects.


1997 ◽  
Vol 9 (1) ◽  
pp. 49-60
Author(s):  
Vanessa Wright

The spectrum of abdominal wall defects includes exomphalos (omphalocoele), gastroschisis, and bladder and cloacal exstrophy. These congenital anomalies are readily recognised on a prenatal ultrasound scan. A raised maternal serum alpha-fetoprotein (MSAFP) should also prompt an ultrasound examination looking specifically for these anomalies, as well as neural tube defects. The influence of prenatal diagnosis on the peri- and postnatal management and outcome is still the subject of debate. Most published work relies on patient numbers too small to be of use statistically. Attempting to draw objective conclusions is made difficult because published series come from units with differing facilities and levels of expertise in the many professional groups involved in the management of these often complex anomalies.


2019 ◽  
Vol 12 (1) ◽  
pp. bcr-2018-226076
Author(s):  
Prashant Kumar ◽  
Rishi Nayyar ◽  
Amlesh Seth ◽  
Deepti Gupta

The exstrophy–epispadias complex represents a spectrum of genitourinary malformations ranging from simple glanular epispadias to an overwhelming multisystem defect, cloacal exstrophy. Neonatal total reconstruction of bladder exstrophy–epispadias complex is the treatment of choice. An adult patient presenting with untreated exstrophy is very rare. Malignant transformation, commonly adenocarcinoma, in such cases is a known complication due to mucosal metaplasia of urothelium. Management in such cases necessitates a radical surgical procedure that often results in a massive defect in the anterior abdominal wall. Providing a cover for such defects is a challenging task for the reconstructive surgeon. Local skin flaps and wide mobilisation of the rectus muscle are the usually employed techniques for closure of such defects. However, these may be inadequate in extremely large defects such as those encountered in our patients. We, hereby, describe our technique of closure of the abdominal wall defect using a pedicled anterolateral thigh flap.


2018 ◽  
Vol 0 (4) ◽  
pp. 13-17
Author(s):  
O. V. Panchuk ◽  
V. G. Mishalov ◽  
I. M. Leschishin ◽  
V. F. Simonov ◽  
E. G. Donets ◽  
...  

2017 ◽  
Vol 68 (7) ◽  
pp. 1648-1651
Author(s):  
Bogdan Mihnea Ciuntu ◽  
Ciprian Vasiluta ◽  
Robert Negru ◽  
Roxana Hultoana ◽  
Roxana Ciuntu ◽  
...  

The study aims to assess the significance of negative pressure therapy in the treatment of diabetic foot.The objectives intend to evaluate the healing time required after applying the method and the functional consequences for the patient. A prospective study was conducted on a sample of 37 patients with diabetic foot were monitored their clinical course between September 2014 - April 2017, following negative pressure therapy. There were used vacuum assisted closure devices (VAC � -Hartman) in order to apply negative pressure to the wound, while complying with specified settings (negative pressure, time of use of a kit) in accordance with patients� outcome.There were monitored changes in wound size (planimetric and volumetric measurement), their bacterial load and duration of treatment. Healing was obtained in all cases, to an average hospital stay of 27.3 days and 8 days of therapy application.The negative result of microbial cultures was obtained after an average of 6.45 days by simultaneous application of negative pressure and antibiotic treatment according to the antibiogram. Skin grafts were necessary to close the defect in 4 cases. After basic treatment of the wound, auxiliary methods such as negative pressure contribute to the healing.In patients with diabetic foot who were required surgical intervention, the use of negative pressure therapy yielded a significant benefit in the preservation of the affected limb, after minimal excision.The results we obtained throughout our experience recommend use of NPTW technique as indication for abdominal wall surgery in closing abdominal wall defects, compartment syndrome and surgical site infection after prosthetic mesh.


2008 ◽  
Vol 84 ◽  
pp. S112
Author(s):  
Olivia Williams ◽  
Benedicte Michel ◽  
Graham Hutchings ◽  
Pierre Bernard ◽  
Christian Debauche

Author(s):  
Laura C. HA ◽  
Amanda CRAIG ◽  
Matthew R. GRACE ◽  
Sarah S. OSMUNDSON ◽  
Emily W. TAYLOR ◽  
...  

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