Original article: Quality of life after esophagectomy and endoscopic therapy for Barrett's esophagus with dysplasia

2010 ◽  
Vol 23 (6) ◽  
pp. 458-464 ◽  
Author(s):  
D. Schembre ◽  
A. Arai ◽  
S. Levy ◽  
M. Farrell-Ross ◽  
D. Low
Keyword(s):  
Quality Of Life ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Endoscopic Therapy ◽  
Article Quality

scholarly journals A139 IMPROVED QUALITY OF LIFE AFTER ENDOSCOPIC THERAPY FOR BARRETT’S ESOPHAGUS AND EARLY ESOPHAGEAL CANCER IN SOUTHERN ALBERTA

2021 ◽  
Vol 4 (Supplement_1) ◽  
pp. 125-126
Author(s):  
T Jeyalingam ◽  
M Woo ◽  
S E Congly ◽  
J David ◽  
P J Belletrutti ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Linear Regression ◽  
Multiple Linear Regression ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Endoscopic Therapy ◽  
Negative Impact ◽  
Older Age ◽  
The Impact

Abstract Background In patients with Barrett’s esophagus (BE), endoscopic therapy reduces the risk of progression to invasive esophageal adenocarcinoma (EAC). Data on the impact of endoscopic therapy on patient quality of life (QoL) is limited. Aims We aimed to assess: (1) change in QoL during the course of endoscopic therapy for BE, (2) factors which predict this change, (3) whether achieving complete remission of dysplasia (CRD) or intestinal metaplasia (CRIM) affect the degree of change. Methods We conducted a retrospective observational study using a prospectively maintained database of BE patients treated in Calgary, Alberta from 2013–2020 containing data on demographics, BE disease characteristics and therapeutics, QoL, and follow-up. QoL was determined prior to initiation of therapy and after each treatment session using a validated questionnaire. Descriptive statistics were calculated and change in QoL was compared using a Wilcoxon signed ranks test. Backwards multiple linear regression analysis was performed to determine predictors of change in QoL. Results Of 130 BE patients, 112 (86.1%) were male and 104 (80%) had dysplastic histology or intramucosal carcinoma on index endoscopy. Mean (SD) age was 65.6 (12.0) years. At time of analysis, 76 patients (58.5%) had completed endoscopic therapy, of whom 69 (90.8%) achieved CRIM; 54 patients (41.5%) were still undergoing treatment. There was significant improvement in all QoL measures during the treatment course except for “depression” (Table 1). Patients with CRIM or CRD had reductions in “sleep difficulty” and “negative impact on life” to a significantly greater degree vs patients not achieving CRIM (Δ sleep -0.45 vs 0.0, P=0.002; Δ negative impact -0.4 vs -0.05, P=0.014) or CRD (Δ sleep -0.40 vs +0.60, P=0.002; Δ negative impact -0.40 vs +0.20, P=0.04). Multiple linear regression revealed older age (B=-0.03, P=0.008) and fewer number of EMR sessions (B=0.254, P=0.008) were correlated with greater improvement in QoL. Conclusions Endoscopic therapy improves QoL in BE patients, especially in those achieving CRIM/CRD. Older age and fewer EMRs are correlated with greater improvement in QoL. These results further reinforce the role of endoscopic therapy as the first line treatment of BE and early EAC. Funding Agencies None

ID: 3524554 IMPROVED QUALITY OF LIFE AFTER ENDOSCOPIC THERAPY FOR BARRETT’S ESOPHAGUS AND EARLY ESOPHAGEAL CANCER

2021 ◽  
Vol 93 (6) ◽  
pp. AB293
Author(s):  
Thurarshen Jeyalingam ◽  
Matthew Woo ◽  
Stephen E. Congly ◽  
Joel David ◽  
Paul J. Belletrutti ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Esophageal Cancer ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Endoscopic Therapy ◽  
Early Esophageal Cancer

Mo1196 LONG TERM QUALITY OF LIFE AMONG PATIENTS WITH NEOPLASTIC BARRETT'S ESOPHAGUS FOLLOWING ENDOSCOPIC THERAPY COMPARED TO ESOPHAGECTOMY

2019 ◽  
Vol 89 (6) ◽  
pp. AB459
Author(s):  
Chanakyaram A. Reddy ◽  
Anna Tavakkoli ◽  
Vincent L. Chen ◽  
Sheryl J. Korsnes ◽  
Aarti Bedi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Endoscopic Therapy

Long-Term Quality of Life Following Endoscopic Therapy Compared to Esophagectomy for Neoplastic Barrett’s Esophagus

2020 ◽  
Author(s):  
Chanakyaram A. Reddy ◽  
Anna Tavakkoli ◽  
Vincent L. Chen ◽  
Sheryl Korsnes ◽  
Aarti Oza Bedi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Endoscopic Therapy

The First Prospective Study of the Impact of Endoscopic and Surgical Treatment of Early Barrett's Neoplasia in Barrett's Esophagus on Quality of Life and Fear of Cancer

2011 ◽  
Vol 140 (5) ◽  
pp. S-200-S-201
Author(s):  
Wilda Rosmolen ◽  
Pythia Nieuwkerk ◽  
Mark I. van Berge Henegouwen ◽  
Mirjam Sprangers ◽  
Jacques J. Bergman
Keyword(s):  
Quality Of Life ◽  
Surgical Treatment ◽  
Prospective Study ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Fear Of Cancer ◽  
The Impact

Impact of radiofrequency ablation for Barrett's esophagus on quality of life

Endoscopy ◽  
2011 ◽  
Vol 43 (03) ◽  
pp. 244-244
Author(s):  
E. Akbal ◽  
S. Köklü ◽  
A. Babalı
Keyword(s):  
Quality Of Life ◽  
Radiofrequency Ablation ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus
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