Multicenter, Randomized, Parallel-Group Study of the Safety and Effectiveness of OnabotulinumtoxinA and Hyaluronic Acid Dermal Fillers (24-mg/mL Smooth, Cohesive Gel) Alone and in Combination for Lower Facial Rejuvenation

2010 ◽  
Vol 36 ◽  
pp. 2121-2134 ◽  
Author(s):  
ALASTAIR CARRUTHERS ◽  
JEAN CARRUTHERS ◽  
GARY D. MONHEIT ◽  
PAULA G. DAVIS ◽  
GREG TARDIE
Keyword(s):  
Hyaluronic Acid ◽  
Facial Rejuvenation ◽  
Dermal Fillers ◽  
Parallel Group Study ◽  
Parallel Group ◽  
Cohesive Gel

scholarly journals Concomitant Use of Hyaluronic Acid and Laser in Facial Rejuvenation

2019 ◽  
Vol 43 (4) ◽  
pp. 1061-1070 ◽  
Author(s):  
Fernando Urdiales-Gálvez ◽  
Sandra Martín-Sánchez ◽  
Mónica Maíz-Jiménez ◽  
Antonio Castellano-Miralla ◽  
Leonardo Lionetti-Leone
Keyword(s):  
Hyaluronic Acid ◽  
Botulinum Toxin A ◽  
Scientific Evidence ◽  
Combined Treatment ◽  
Facial Rejuvenation ◽  
Full Description ◽  
Dermal Fillers ◽  
Level Of Evidence ◽  
Laser Technology ◽  
Patient’S Satisfaction

AbstractBackgroundFacial aging is a process that involves many different changes. Therefore, in many patients, it may be necessary to perform a combined treatment. Botulinum toxin A and dermal fillers are the two most popular nonsurgical cosmetic procedures performed globally to treat age-associated changes. However, there are not many studies reporting the concomitant use of dermal fillers and laser technology for facial rejuvenation. This review aims to assess the concomitant use of dermal hyaluronic acid (HA) fillers and laser technology for facial rejuvenation.MethodsThe present updated consensus recommendations are based on the experience and opinions of the authors and on a literature search.ResultsIf a combined procedure (HA and light treatments) is to be performed, on the same day, the panel recommends starting always with the light treatments, avoiding skin manipulations after having injected HA. To customize the therapeutic management, it is crucial to establish a precise diagnosis of the photodamage and loss of volumes suffered by the patients.ConclusionsThe currently available scientific evidence about the combined use of HA fillers and laser–radiofrequency–intense pulsed light (laser/RF/IPL) is limited and encompasses mainly small and nonrandomized studies. Nevertheless, most of these studies found that, on average, the concomitant use (same day) of laser and HA fillers for facial rejuvenation represents an effective and safe strategy which improves clinical results and patient’s satisfaction. Future well-designed clinical studies are needed regarding the effectiveness and safety of combination filler/laser treatments.Level of Evidence IVThis journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authorswww.springer.com/00266.

Patient-reported outcomes in subjects with plaque psoriasis treated with tapinarof cream: Results from a phase 2b, randomized parallel-group study

2018 ◽  
Vol 2 ◽  
pp. S85
Author(s):  
Neal Bhatia ◽  
David Rubenstein ◽  
Anna M Tallman ◽  
James Lee
Keyword(s):  
Plaque Psoriasis ◽  
Patient Reported Outcomes ◽  
Parallel Group Study ◽  
Parallel Group ◽  
Patient Reported

Abstract not available. Disclosures: Study sponsored by Dermavant.Copyright 2018 SKIN

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