scholarly journals Antiepileptic Effects of Tiagabine, a Selective GABA Uptake Inhibitor, in the Rat Kindling Model of Temporal Lobe Epilepsy

Epilepsia ◽  
1997 ◽  
Vol 38 (9) ◽  
pp. 966-974 ◽  
Author(s):  
Kiyoshi Morimoto ◽  
Hitoshi Sato ◽  
Yoshitaka Yamamoto ◽  
Takemi Watanabe ◽  
Hiroshi Suwaki
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Gaba Uptake ◽  
Uptake Inhibitor ◽  
Kindling Model ◽  
Gaba Uptake Inhibitor

Anticonvulsant activity of the glial GABA uptake inhibitor, THAO, in chemical seizures

1989 ◽  
Vol 168 (2) ◽  
pp. 265-268 ◽  
Author(s):  
Susan F. Gonsalves ◽  
Bonnie Twitchell ◽  
Robert E. Harbaugh ◽  
Povl Krogsgaard-Larsen ◽  
Arne Schousboe
Keyword(s):  
Anticonvulsant Activity ◽  
Gaba Uptake ◽  
Uptake Inhibitor ◽  
Gaba Uptake Inhibitor

6-(4-Phenyl-benzyloxy-methyl) guvacine. Synthesis, GABA uptake inhibitor and muscarinic properties

1996 ◽  
Vol 6 (24) ◽  
pp. 3025-3028 ◽  
Author(s):  
Philippe Bisel ◽  
Jean Pierre Gies ◽  
Gilbert Schlewer ◽  
Camille G. Wermuth
Keyword(s):  
Gaba Uptake ◽  
Uptake Inhibitor ◽  
Gaba Uptake Inhibitor

Synthesis of analogues of GABA. VIII. Selective a-alkylation and γ-halogenation of the dianion from α,β-unsaturated nipecotic acid derivatives

1983 ◽  
Vol 36 (3) ◽  
pp. 601 ◽  
Author(s):  
RD Allan ◽  
J Fong
Keyword(s):  
Amino Acid ◽  
Carboxylic Acid ◽  
Alkylating Agents ◽  
Gaba Uptake ◽  
Nipecotic Acid ◽  
Uptake Inhibitor ◽  
Gaba Uptake Inhibitor ◽  
Unsaturated Amino Acid

1,2,3,6-Tetrahydropyridine-3-carboxylic acid (3), the β, γ-unsaturated derivative of the GABA uptake inhibitor nipecotic acid (1), has been synthesized by deconjugation via the dilithium salt of the N-t-butyloxycarbonyl-protected intermediate (6). Substitution of the intermediate with alkylating agents or an aldehyde gave predominantly a-alkylated products but chlorination with N-chlorosuccinimide provided a route to the γ-substituted unsaturated amino acid (13a).

scholarly journals Parawixin2, a novel non-selective GABA uptake inhibitor from Parawixia bistriata spider venom, inhibits pentylenetetrazole-induced chemical kindling in rats

2013 ◽  
Vol 543 ◽  
pp. 12-16 ◽  
Author(s):  
Erica A. Gelfuso ◽  
José L. Liberato ◽  
Alexandra O.S. Cunha ◽  
Márcia R. Mortari ◽  
Renê O. Beleboni ◽  
...  
Keyword(s):  
Spider Venom ◽  
Gaba Uptake ◽  
Uptake Inhibitor ◽  
Chemical Kindling ◽  
Gaba Uptake Inhibitor ◽  
Parawixia Bistriata

scholarly journals The Involvement of Apoptotic Neural Damages in a Patient with Intractable Temporal Lobe Epilepsy and in a Kindling Model

Epilepsia ◽  
2000 ◽  
Vol 41 (s9) ◽  
pp. 50-50
Author(s):  
Hiroto Iwasa ◽  
Shuichi Kikuchi ◽  
Seiichirou Mine ◽  
Hiro Miyagishima ◽  
Yasuo Iwadate
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Kindling Model
Sign in / Sign up

Export Citation Format

Share Document