Predicting Sudden Cardiac Death From T Wave Alternans of the Surface Electrocardiogram:.

1996 ◽  
Vol 7 (11) ◽  
pp. 1095-1111 ◽  
Author(s):  
DAVID S. ROSENBAUM ◽  
PAUL ALBRECHT ◽  
RICHARD J. COHEN
Keyword(s):  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
T Wave ◽  
T Wave Alternans ◽  
Surface Electrocardiogram

RESEARCH THE VALUE OF THE COMBINATION OF T WAVE ALTERNANS AND NT-PROBNT IN PREDICTING SUDDEN CARDIAC DEATH

2012 ◽  
pp. 74-83
Author(s):  
Anh Tien Hoang ◽  
Nhat Quang Nguyen
Keyword(s):  
Myocardial Infarction ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Ventricular Arrhythmias ◽  
Healthy Person ◽  
Treadmill Test ◽  
T Wave ◽  
T Wave Alternans

Background: Decades of research now link TWA with inducible and spontaneous clinical ventricular arrhythmias. This bench-to-bedside foundation makes TWA, NT-ProBNP a very plausible index of susceptibility to ventricular arrythmia, and motivates the need to define optimal combination of TWA and NT-ProBNP in predicting ventricular arrythmia in myocardial infarction patients. We research this study with 2 targets: 1. To evaluate the role of TWA in predicting sudden cardiac death in myocardial infarction patients. 2. To evaluate the role of NT-ProBNP in predicting sudden cardiac death in myocardial infarction patients 3. Evaluate the role of the combined NT-ProBNP and TWA in predicting sudden cardiac death in myocardial infarction patients. Methods: Prospective study with follow up the mortality in 2 years: 71 chronic myocardial infarction patients admitted to hospital from 5/2009 to 5/20011 and 50 healthy person was done treadmill test to caculate TWA; ECG, echocardiography, NT-ProBNP. Results: Cut-off point of NT-ProBNP in predicting sudden cardiac death is 3168 pg/ml; AUC = 0,86 (95% CI: 0,72 - 0,91); Cut-off point of TWA in predicting sudden cardiac death is 107 µV; AUC = 0,81 (95% CI: 0,69 - 0,87); NT-ProBNP can predict sudden cardiac death with OR= 7,26 (p<0,01); TWA can predict sudden cardiac death with OR= 8,45 (p<0,01). The combined NT-ProBNP and TWA in predicting ventricular arrythmia in heart failure patients: OR= 17,91 (p<0,001). Conclusions: The combined NT-ProBNP and TWA have the best predict value of sudden cardiac death in myocardial infarction patients, compare to NT-ProBNP or TWA alone

Importance of regional specificity of T-wave alternans in assessing risk for cardiovascular mortality and sudden cardiac death during routine exercise testing

Heart Rhythm ◽  
2011 ◽  
Vol 8 (3) ◽  
pp. 385-390 ◽  
Author(s):  
Johanna Leino ◽  
Richard L. Verrier ◽  
Mikko Minkkinen ◽  
Terho Lehtimäki ◽  
Jari Viik ◽  
...  
Keyword(s):  
Sudden Cardiac Death ◽  
Exercise Testing ◽  
Cardiovascular Mortality ◽  
Cardiac Death ◽  
T Wave ◽  
Regional Specificity ◽  
T Wave Alternans
Sign in / Sign up

Export Citation Format

Share Document