Immunosuppression and gingival overgrowth: gene and protein expression profiles of collagen turnover in FK506-treated human gingival fibroblasts

2005 ◽  
Vol 32 (2) ◽  
pp. 167-173 ◽  
Author(s):  
Nicoletta Gagliano ◽  
Claudia Moscheni ◽  
Claudia Dellavia ◽  
Giordano Stabellini ◽  
Virgilio F. Ferrario ◽  
...  
2019 ◽  
Vol 129 (9) ◽  
pp. 871-881 ◽  
Author(s):  
Han-Chung Lee ◽  
Hadri Hadi Md Yusof ◽  
Melody Pui-Yee Leong ◽  
Shahidee Zainal Abidin ◽  
Eryse Amira Seth ◽  
...  

2002 ◽  
Vol 6 (1) ◽  
pp. 39-60 ◽  
Author(s):  
Alex S. Beliaev ◽  
Dorothea K. Thompson ◽  
Tripti Khare ◽  
Hanjo Lim ◽  
Craig C. Brandt ◽  
...  

PLoS ONE ◽  
2016 ◽  
Vol 11 (9) ◽  
pp. e0163561 ◽  
Author(s):  
Shuji Hamauchi ◽  
Hideo Shichinohe ◽  
Haruto Uchino ◽  
Shigeru Yamaguchi ◽  
Naoki Nakayama ◽  
...  

2021 ◽  
Author(s):  
Yong-Wei Fu

AbstractAlthough deubiquitinating enzymes (DUBs) such as CYLD, A20 and OTULIN are expressed in multiple tissues and thought to be linked with inflammatory diseases, their expression in periodontal tissues remains to be determined. This research was designed to assess the expression of CYLD, A20 and OTULIN in human gingiva, and to evaluate the regulation of these DUBs in human gingival fibroblasts (HGFs) upon different stimuli. Immunohistochemistry assay was conducted to determine the expression of CYLD, A20 and OTULIN in human gingiva. Immunofluorescence assay was employed to observe the protein expression of CYLD, A20 and OTULIN in HGFs. RT-PCR and western blots were carried out to assess gene and protein expression changes of these DUBs in HGFs upon LPS or TNF-α. CYLD, A20 and OTULIN were found to be expressed in human gingiva and HGFs. Further, the expression of CYLD, A20 and OTULIN in HGFs exhibited distinct regulation by different stimuli. Our findings suggest that CYLD, A20 and OTULIN might play a role in the progression of periodontitis.


2011 ◽  
Vol 10 (3) ◽  
pp. 163-165 ◽  
Author(s):  
Edecio Cunha-Neto ◽  
Priscila C. Teixeira ◽  
Simone G. Fonseca ◽  
Angelina M. Bilate ◽  
Jorge Kalil

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