BLACK CUMIN SEED (NIGELLA SATIVA LINN.) OIL AND ITS FRACTIONS PROTECT AGAINST BETA AMYLOID PEPTIDE-INDUCED TOXICITY IN PRIMARY CEREBELLAR GRANULE NEURONS

2008 ◽  
Vol 15 (4) ◽  
pp. 519-533 ◽  
Author(s):  
NORSHARINA ISMAIL ◽  
MAZNAH ISMAIL ◽  
LATIFFAH A. LATIFF ◽  
MUSALMAH MAZLAN ◽  
ABDALBASIT A. MARIOD
Keyword(s):  
Nigella Sativa ◽  
Beta Amyloid ◽  
Amyloid Peptide ◽  
Cerebellar Granule Neurons ◽  
Granule Neurons ◽  
Cerebellar Granule ◽  
Black Cumin ◽  
Beta Amyloid Peptide ◽  
Black Cumin Seed ◽  
Cumin Seed

scholarly journals EFFECTIVENESS TEST OF BLACK CUMIN SEEDS (NIGELLA SATIVA) EXTRACT ON THE GROWTH OF KLEBSIELLA PNEUMONIAE AND PSEUDOMONAS AERUGINOSA BACTERIA

2021 ◽  
Vol 7 (2) ◽  
pp. 130-138
Author(s):  
Nadya Nazimuddin Putri ◽  
Linda Chiuman ◽  
Chrismis Novalinda Ginting ◽  
Ermi Girsang
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Klebsiella Pneumoniae ◽  
Nigella Sativa ◽  
Ethanol Extract ◽  
Inhibition Zone ◽  
Seed Extract ◽  
Diffusion Method ◽  
Black Cumin ◽  
Black Cumin Seed ◽  
Cumin Seed

Black cumin seeds are known to have beneficial contents as antibacterial. This study aimed to determine the effectiveness of black cumin seed extract (Nigella sativa) on the growth of Klebsiella pneumoniae and Pseudomonas aeruginosa. The method used was the disc diffusion method. The ethanol extract of black cumin seeds gain by maceration method and was made into various concentration (5, 7.5, 10, 12.5, and 15)%. For positive control, ciprofloxacin disc were used and negative control used distilled water. The research model used was in vitro experimental research. The results showed that ethanol extract of black cumin seeds have antibacterial activity against Klebsiella pneumoniae with inhibition zone diameters (4.5, 6.7, 10.1, 11, 12.8) mm, Pseudomonas aeruginosa with inhibition zone diameters (7.5, 12, 12.6, 13.4, 15.6) mm, positive controls respectively (24.3 and 20.7) mm and negative controls (0). It can be concluded that black cumin seed extract has an inhibiting effect on the growth of Klebsiella pneumoniae and Pseudomonas aeruginosa.

scholarly journals Ethanol Extract of Black Cumin Seed (Nigella Sativa) Reduces Expression Kidney iNOS in Mice Model Preeclampsia

2019 ◽  
Vol 5 (2) ◽  
pp. 88
Author(s):  
Rubiati Hipni
Keyword(s):  
Nigella Sativa ◽  
Ethanol Extract ◽  
Negative Control ◽  
Inos Expression ◽  
Control Group ◽  
Mice Model ◽  
Control Group Design ◽  
Black Cumin ◽  
Black Cumin Seed ◽  
Cumin Seed

This study aims to analyze the effect of ethanol extract of black cumin seeds (Nigella Sativa) on iNOS expression in the kidney of mice model preeclampsia. Design This study uses an experimental design with a posttest only control group design. Using a mice model preeclampsia. This study was divided into 6 groups: negative control, positive control (preeclampsia model), model + black cumin seed extract 500 mg/KgBB/day, 1000 mg/KgBB/day, 1500 mg/KgBB/day, and 2000 mg/KgBB/day days, after surgery on mice then examined iNOS Kidney expression by methods Immunohistochemical. Data from observations were analyzed by one way ANOVA test. The result there is an effect of ethanol extract of black cumin seeds on renal iNOS expression in mice model preeclampsia (p <0.05) at doses of 500mg, 1000mg, 1500mg, and 2000mg on decreasing renal iNOS expression. The conclusion Ethanol extract of black cumin seeds (Nigella sativa) can reduce iNOS Kidney expression in Mice Preeclampsia.

Effect of dietary black cumin seed (Nigella sativa) on performance, immune status, and serum metabolites of small ruminants: A meta-analysis

2021 ◽  
pp. 106521
Author(s):  
Sadarman ◽  
Dewi Febrina ◽  
Yendraliza ◽  
Miftahush Shirothul Haq ◽  
Rizki Amalia Nurfitriani ◽  
...  
Keyword(s):  
Immune Status ◽  
Nigella Sativa ◽  
Meta Analysis ◽  
Small Ruminants ◽  
Serum Metabolites ◽  
Black Cumin ◽  
Black Cumin Seed ◽  
Cumin Seed

scholarly journals Nigella sativa (Black Cumin) Seed Extract Alleviates Symptoms of Allergic Diarrhea in Mice, Involving Opioid Receptors

PLoS ONE ◽  
2012 ◽  
Vol 7 (6) ◽  
pp. e39841 ◽  
Author(s):  
Swantje C. Duncker ◽  
David Philippe ◽  
Christine Martin-Paschoud ◽  
Mireille Moser ◽  
Annick Mercenier ◽  
...  
Keyword(s):  
Opioid Receptors ◽  
Nigella Sativa ◽  
Seed Extract ◽  
Black Cumin ◽  
Black Cumin Seed ◽  
Cumin Seed

scholarly journals TO STUDY THE EFFECT OF DIETARY BLACK SEED (NIGELLA SATIVA) SUPPLEMENTATION ON THE MEAT QUALITY OF LABEO ROHITA

2021 ◽  
Vol 6 (5) ◽  
Author(s):  
Israr Maqbool ◽  
Ariana Ali ◽  
Muhammad Ashraf ◽  
Tahir Shehzad ◽  
Muhammad Sarfraz ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Unsaturated Fatty Acids ◽  
Labeo Rohita ◽  
Nigella Sativa ◽  
Saturated Fatty Acids ◽  
Fish Diet ◽  
Black Cumin ◽  
Black Cumin Seed ◽  
Cumin Seed

Purpose In this study, we looked at the benefits of a Nigella sativa supplementation diet and how nonessential fatty acids were controlled in Labeo rohit. Methods For a total of 28 days, Labeo rohita were fed various supplemental diets including 0.00 percent, 1%, and 2.5 percent black cumin seed. The effect of black cumin seed on Labeo rohita's fatty acid profile was investigated. Saturated fatty acids were high at the start of the trial, but they reduced after supplementation, and the difference in fatty acids between groups was statistically significant (?0.05). When black cumin seed was added to fish diet, it reduced saturated fatty acids (methyl heptadedecanoate and methyl stearate) while increasing unsaturated fatty acids (gamma-linolenic acid and methyl cis-5,8,11,14 eicosatetraenoic) ConclusionIn conclusion , adding 2.5 percent black cumin seed bin feed enhanced un-saturated fatty acids, which improved the quality of the fish flesh.

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