DMBT1 involvement in the human aortic endothelial cell response toStreptococcus mutans

2019 ◽  
Vol 34 (3) ◽  
pp. 108-117 ◽  
Author(s):  
Takahiko Oho ◽  
Emi Nagata
1996 ◽  
Vol 32 (1-3) ◽  
pp. 153-156 ◽  
Author(s):  
Andreas Papapetropoulos ◽  
James W Ryan ◽  
Alexander Antonov ◽  
Renu Virmani ◽  
Frank D Kolodgie ◽  
...  

2014 ◽  
Vol 9 (1) ◽  
pp. 421 ◽  
Author(s):  
Pilar Formentín ◽  
María Alba ◽  
Úrsula Catalán ◽  
Sara Fernández-Castillejo ◽  
Josep Pallarès ◽  
...  

2006 ◽  
Vol 20 (4) ◽  
Author(s):  
Jean Tsou ◽  
Harold J Ting ◽  
Ulrich Y Schaff ◽  
Michael F Insana ◽  
Scott I Simon

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Jeny Shklover ◽  
James McMasters ◽  
Alba Alfonso-Garcia ◽  
Manuela Lopera Higuita ◽  
Alyssa Panitch ◽  
...  

Abstract Xenogeneic biomaterials contain biologically relevant extracellular matrix (ECM) composition and organization, making them potentially ideal surgical grafts and tissue engineering scaffolds. Defining the effect of ECM niche (e.g., basement membrane vs. non-basement membrane) on repopulating cell phenotype and function has important implications for use of xenogeneic biomaterials, particularly in vascular applications. We aim to understand how serous (i.e., basement membrane) versus fibrous (i.e., non-basement membrane) ECM niche of antigen-removed bovine pericardium (AR-BP) scaffolds influence human aortic endothelial cell (hAEC) adhesion, growth, phenotype, inflammatory response and laminin production. At low and moderate seeding densities hAEC proliferation was significantly increased on the serous side. Similarly, ECM niche modulated cellular morphology, with serous side seeding resulting in a more rounded aspect ratio and intact endothelial layer formation. At moderate seeding densities, hAEC production of human laminin was enhanced following serous seeding. Finally, inflammatory marker and pro-inflammatory cytokine expression decreased following long-term cell growth regardless of seeding side. This work demonstrates that at low and moderate seeding densities AR-BP sidedness significantly impacts endothelial cell growth, morphology, human laminin production, and inflammatory state. These findings suggest that ECM niche has a role in modulating response of repopulating recipient cells toward AR-BP scaffolds for vascular applications.


2016 ◽  
Vol 112 (3) ◽  
pp. 702-713 ◽  
Author(s):  
Zahia Touat-Hamici ◽  
Henri Weidmann ◽  
Yuna Blum ◽  
Carole Proust ◽  
Hervé Durand ◽  
...  

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