scholarly journals Doubly robust estimation of the local average treatment effect curve

Author(s):  
Elizabeth L. Ogburn ◽  
Andrea Rotnitzky ◽  
James M. Robins
2018 ◽  
Vol 238 (3-4) ◽  
pp. 243-293 ◽  
Author(s):  
Jason Ansel ◽  
Han Hong ◽  
and Jessie Li

Abstract We investigate estimation and inference of the (local) average treatment effect parameter when a binary instrumental variable is generated by a randomized or conditionally randomized experiment. Under i.i.d. sampling, we show that adding covariates and their interactions with the instrument will weakly improve estimation precision of the (local) average treatment effect, but the robust OLS (2SLS) standard errors will no longer be valid. We provide an analytic correction that is easy to implement and demonstrate through Monte Carlo simulations and an empirical application the interacted estimator’s efficiency gains over the unadjusted estimator and the uninteracted covariate adjusted estimator. We also generalize our results to covariate adaptive randomization where the treatment assignment is not i.i.d., thus extending the recent contributions of Bugni, F., I.A. Canay, A.M. Shaikh (2017a), Inference Under Covariate-Adaptive Randomization. Working Paper and Bugni, F., I.A. Canay, A.M. Shaikh (2017b), Inference Under Covariate-Adaptive Randomization with Multiple Treatments. Working Paper to allow for the case of non-compliance.


PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249642
Author(s):  
Byeong Yeob Choi

Instrumental variable (IV) analysis is used to address unmeasured confounding when comparing two nonrandomized treatment groups. The local average treatment effect (LATE) is a causal estimand that can be identified by an IV. The LATE approach is appealing because its identification relies on weaker assumptions than those in other IV approaches requiring a homogeneous treatment effect assumption. If the instrument is confounded by some covariates, then one can use a weighting estimator, for which the outcome and treatment are weighted by instrumental propensity scores. The weighting estimator for the LATE has a large variance when the IV is weak and the target population, i.e., the compliers, is relatively small. We propose a truncated LATE that can be estimated more reliably than the regular LATE in the presence of a weak IV. In our approach, subjects who contribute substantially to the weak IV are identified by their probabilities of being compliers, and they are removed based on a pre-specified threshold. We discuss interpretation of the proposed estimand and related inference method. Simulation and real data experiments demonstrate that the proposed truncated LATE can be estimated more precisely than the standard LATE.


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