Residual bacterial detection rates after primary culture as determined by secondary culture and rapid testing in platelet components: A systematic review and meta‐analysis

Transfusion ◽  
2020 ◽  
Author(s):  
Brandon S. Walker ◽  
Sandra K. White ◽  
Robert L. Schmidt ◽  
Ryan A. Metcalf
Keyword(s):  
Systematic Review ◽  
Primary Culture ◽  
Meta Analysis ◽  
Rapid Testing ◽  
Bacterial Detection ◽  
Detection Rates ◽  
Secondary Culture

scholarly journals Systematic review with meta-analysis: age-related malignancy detection rates at upper gastrointestinal endoscopy

2020 ◽  
Vol 13 ◽  
pp. 175628482095922
Author(s):  
Judith J. de Jong ◽  
Marten A. Lantinga ◽  
Ina M. E. Thijs ◽  
Philip R. de Reuver ◽  
Joost P. H. Drenth
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Detection Rates ◽  
Gi Endoscopy ◽  
Upper Gi ◽  
Age Related ◽  
Upper Gi Endoscopy ◽  
Age Limits ◽  
Upper Gi Malignancy ◽  
Upper Gastrointestinal

Background: Age is an important and objective risk factor for upper gastrointestinal (GI) malignancy. The accuracy of various age limits to detect upper GI malignancy is unclear. Determination of this accuracy may aid in the decision to refer symptomatic patients for upper GI endoscopy. The aim of this analysis was to synthesize data on upper GI malignancy detection rates for various age limits worldwide through meta-analysis. Methods: We searched MEDLINE, EMBASE, and Web of Science in November 2018. Selection criteria included studies addressing malignant findings at upper GI endoscopy in a symptomatic population reporting age at time of diagnosis. Meta-analyses were conducted to derive continent-specific cancer detection rates. Results: A total of 33 studies including 346,641 patients across 21 countries fulfilled the inclusion criteria. To detect >80% of malignant cases all symptomatic patients over 40 years of age should be investigated in Africa, over 50 years of age in South America and Asia, and over 55 years of age in North America and Europe. Conclusion: This systematic review and meta-analysis provides data on intercontinental variation in age at time of upper GI malignancy diagnosis in symptomatic patients referred for upper GI endoscopy. Guideline recommendations for age-based selection should be tailored to local age-related detection rates.

scholarly journals SARS-CoV-2 Detection in Different Respiratory Sites: A Systematic Review and Meta-Analysis

2020 ◽  
Author(s):  
Abbas Mohammadi ◽  
Elmira Esmaeilzadeh ◽  
Yijia Li ◽  
Ronald J Bosch ◽  
Jonathan Li
Keyword(s):  
Systematic Review ◽  
Symptom Onset ◽  
Meta Analysis ◽  
Nasopharyngeal Swab ◽  
Inclusion Criteria ◽  
Rna Detection ◽  
Timely Initiation ◽  
Detection Rates ◽  
Diverse Range ◽  
Oropharyngeal Swab

Background: The accurate detection of SARS-CoV-2 through respiratory sampling is critical for the prevention of further transmission and the timely initiation of treatment for COVID-19. There is a diverse range of SARS-CoV-2 detection rates in reported studies, with uncertainty as to the optimal sampling strategy for COVID-19 diagnosis and monitoring. Methods: We performed a systematic review and meta-analysis of studies comparing respiratory sampling strategies for the detection of SARS-CoV-2 RNA. The inclusion criteria were studies that assessed at least two respiratory sampling sites (oropharyngeal swab, nasopharyngeal swab, and sputum) in participants with COVID-19. The percentage positive tests were compared between sampling modalities by constructing a Z-test assuming independence and using the standard errors obtained from the random effects meta-analysis. Findings: From 1039 total studies, we identified 11 studies that met our inclusion criteria, with SARS-CoV-2 testing results from a total of 3442 respiratory tract specimens. Compared to nasopharyngeal swab sampling, sputum testing resulted in significantly higher rates of SARS-CoV-2 RNA detection while oropharyngeal swab testing had lower rates of viral RNA detection. Earlier sampling after symptom onset was associated with improved detection rates, but the differences in SARS-CoV-2 RNA detection by sampling method was consistent regardless of the duration of symptoms. Interpretation: The results support sputum sampling as a primary method of COVID-19 diagnosis and monitoring, and highlight the importance of early testing after symptom onset to increase the rates of COVID-19 diagnosis.

scholarly journals Comparative evaluation of digital mammography and film mammography: systematic review and meta-analysis

2011 ◽  
Vol 129 (4) ◽  
pp. 250-260 ◽  
Author(s):  
Wagner Iared ◽  
David Carlos Shigueoka ◽  
Maria Regina Torloni ◽  
Fernanda Garozzo Velloni ◽  
Sérgio Aron Ajzen ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cancer Detection ◽  
Digital Mammography ◽  
Digital Technology ◽  
Reference Lists ◽  
Meta Analysis ◽  
Analysis Method ◽  
Detection Rates ◽  
Randomized Controlled ◽  
Patient Recall

CONTEXT AND OBJECTIVE: Mammography is the best method for breast-cancer screening and is capable of reducing mortality rates. Studies that have assessed the clinical impact of mammography have been carried out using film mammography. Digital mammography has been proposed as a substitute for film mammography given the benefits inherent to digital technology. The aim of this study was to compare the performance of digital and film mammography. DESIGN: Systematic review and meta-analysis. METHOD: The Medline, Scopus, Embase and Lilacs databases were searched looking for paired studies, cohorts and randomized controlled trials published up to 2009 that compared the performance of digital and film mammography, with regard to cancer detection, recall rates and tumor characteristics. The reference lists of included studies were checked for any relevant citations. RESULTS: A total of 11 studies involving 190,322 digital and 638,348 film mammography images were included. The cancer detection rates were significantly higher for digital mammography than for film mammography (risk relative, RR = 1.17; 95% confidence interval, CI = 1.06-1.29; I² = 19%). The advantage of digital mammography seemed greatest among patients between 50 and 60 years of age. There were no significant differences between the two methods regarding patient recall rates or the characteristics of the tumors detected. CONCLUSION: The cancer detection rates using digital mammography are slightly higher than the rates using film mammography. There are no significant differences in recall rates between film and digital mammography. The characteristics of the tumors are similar in patients undergoing the two methods.

Mo1980 Electronic Chromoendoscopy Techniques Significantly Improve Detection Rates of Flat Adenomas Compared to White Light Colonoscopy: A Systematic Review and Meta-Analysis

2016 ◽  
Vol 83 (5) ◽  
pp. AB482
Author(s):  
Madhav Desai ◽  
Neil Gupta ◽  
Abhishek Choudhary ◽  
Prashanth Vennalaganti ◽  
Sreekar Vennelaganti ◽  
...  
Keyword(s):  
Systematic Review ◽  
White Light ◽  
Meta Analysis ◽  
Detection Rates ◽  
Flat Adenomas

scholarly journals Diagnostic accuracy of magnetic resonance imaging targeted biopsy techniques compared to transrectal ultrasound guided biopsy of the prostate: a systematic review and meta-analysis

2021 ◽  
Author(s):  
E. J. Bass ◽  
A. Pantovic ◽  
M. J. Connor ◽  
S. Loeb ◽  
A. R. Rastinehad ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Transrectal Ultrasound ◽  
Significant Heterogeneity ◽  
Visual Estimation ◽  
Ultrasound Guided ◽  
Detection Rates ◽  
Randomized Controlled ◽  
Guided Biopsy ◽  
Clinically Significant

Abstract Background Multiparametric MRI localizes cancer in the prostate, allowing for MRI guided biopsy (MRI-GB) 43 alongside transrectal ultrasound-guided systematic biopsy (TRUS-GB). Three MRI-GB approaches exist; visual estimation (COG-TB); fusion software-assisted (FUS-TB) and MRI ‘in-bore’ biopsy (IB-TB). It is unknown whether any of these are superior. We conducted a systematic review and meta-analysis to address three questions. First, whether MRI-GB is superior to TRUS-GB at detecting clinically significant PCa (csPCa). Second, whether MRI-GB is superior to TRUS-GB at avoiding detection of insignificant PCa. Third, whether any MRI-GB strategy is superior at detecting csPCa. Methods A systematic literature review from 2015 to 2019 was performed in accordance with the START recommendations. Studies reporting PCa detection rates, employing MRI-GB and TRUS-GB were included and evaluated using the QUADAS-2 checklist. 1553 studies were found, of which 43 were included in the meta-analysis. Results For csPCa, MRI-GB was superior in detection to TRUS-GB (0.83 vs. 0.63 [p = 0.02]). MRI-GB was superior in detection to TRUS-GB at avoiding detection of insignificant PCa. No MRI-GB technique was superior at detecting csPCa (IB-TB 0.87; COG TB 0.81; FUS-TB 0.81, [p = 0.55]). There was significant heterogeneity observed between the included studies. Conclusions In patients with suspected PCa on MRI, MRI-GB offers superior rates of csPCa detection and reduces detection of insignificant PCa compared to TRUS-GB. No individual MRI-GB technique was found to be better in csPCa detection. Prospective adequately powered randomized controlled trials are required.

scholarly journals Comparative Effectiveness of Fecal Immunochemical Tests versus Flexible Sigmoidoscopy for Colorectal Cancer Screening: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

2021 ◽  
Author(s):  
Hemant Mutneja ◽  
Rohit Agrawal ◽  
Abhishek Bhurwal ◽  
Shilpa Arora ◽  
Andrew Go ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Systematic Review ◽  
Clinical Trials ◽  
Randomized Clinical Trials ◽  
Flexible Sigmoidoscopy ◽  
Colorectal Neoplasia ◽  
Meta Analysis ◽  
Detection Rates ◽  
Crc Screening ◽  
Advanced Colorectal Neoplasia

Background and Aims: Fecal immunochemical tests (FITs) and flexible sigmoidoscopies are commonly used modalities for colorectal cancer (CRC) screening. We performed a systematic review and meta-analysis to compare the effectiveness of FIT and sigmoidoscopy in CRC screening. Methods: PRISMA statement and Cochrane guidelines were followed for this review. Digital dissertation databases were searched from inception till December 1st 2020 and randomized clinical trials comparing the detection rates of CRC for FIT and sigmoidoscopy were included. Outcomes for analysis included participation rates and detection rates of CRC, advanced adenomas and advanced colorectal neoplasia for both screening modalities. Results: Five randomized clinical trials with a total of 261,755 patients were included for the analysis. The participation rate for FIT was significantly higher compared to flexible sigmoidoscopy (OR 2.11, 95% CI 1.29-3.44, p=0.003). In intention-to-screen analysis, the detection rate for advanced colorectal neoplasia was significantly lower with FIT (OR 0.62, 95% CI 0.45-0.84, p=0.002) as compared to flexible sigmoidoscopy but not statistically different for CRC (OR 1.15, 95% CI 0.65-2.02, p=0.63). Conclusion: Despite lower participation amongst patients, CRC screening with flexible sigmoidoscopy leads to higher detection of advanced colorectal neoplasia, when compared to a single round of fecal immunochemical testing.

scholarly journals Prevalence and Possible Role of Candida Species in Patients with Psoriasis: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Aldona Pietrzak ◽  
Ewelina Grywalska ◽  
Mateusz Socha ◽  
Jacek Roliński ◽  
Kinga Franciszkiewicz-Pietrzak ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Fungal Colonization ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Cross Sectional ◽  
Detection Rates ◽  
Central Register ◽  
Cross Sectional Studies

Although fungal colonization is implicated in the pathogenesis of psoriasis, its prevalence remains unclear. The aim of this systematic review and meta-analysis was to provide an overview on the prevalence of Candida species in patients with psoriasis. We searched databases (MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and http://clinicaltrials.gov) to identify studies involving subjects of any age with an established diagnosis of psoriasis and healthy controls, who were tested for carriage of Candida spp. on the skin or mucosal membranes (or saliva and stool), or presented with clinical candidiasis with microbiologically confirmed etiology. We identified nine cross-sectional studies including a total of 1038 subjects with psoriasis (psoriatics) and 669 controls. We found Candida species detection rates for psoriatics were significantly higher than those in the controls, especially in the oral mucosa milieux. These results suggest psoriasis may be one of the systemic diseases that predispose to oral Candida spp. carriage and infection.

1021 DISTAL ATTACHMENTS DO NOT IMPROVE SSP DETECTION RATES DURING COLONOSCOPY: A SYSTEMATIC REVIEW AND META-ANALYSIS

2019 ◽  
Vol 89 (6) ◽  
pp. AB128
Author(s):  
Muhammad Aziz ◽  
Madhav Desai ◽  
Seemeen Hassan ◽  
Rawish Fatima ◽  
Chandra S. Dasari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Detection Rates
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