Negative pressure wound therapy using polyvinyl alcohol foam to bolster full-thickness mesh skin grafts in dogs

Abstract Degloving, a skin and subcutis avulsion, is a severe traumatic injury sometimes caused by rolling wheels or machines. Although avulsed flaps are often readapted to its original site, most of these tissues become necrotic. Due to the extensive skin and soft tissue deficiency caused by necrosis, treatment becomes difficult. Skin grafts harvested from avulsed flaps may be used to treat degloving injuries, while negative pressure wound therapy (NPWT) is used to secure the grafts. Commonly used porous polyurethane foam wound fillers are difficult to set in circumferential extremity degloving injuries; gauze-based wound fillers are easier to use and cause less pain during dressing changes. We present a case of an extensive, full-circumference left lower-extremity degloving injury, treated using NPWT with gauze-based wound fillers for fixation of skin grafts harvested from avulsed flaps after hydrosurgical debridement. For complex wound geometries, gauze-based wound fillers can be easily applied for skin graft immobilization.

Download Full-text

Prospective Randomized Controlled Trial Comparing Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy

Journal of Burn Care & Research ◽

10.1097/bcr.0000000000000089 ◽

2015 ◽

Vol 36 (2) ◽

pp. 324-328 ◽

Cited By ~ 12

Author(s):

Trang Q. Nguyen ◽

Mieczyslawa Franczyk ◽

Justine C. Lee ◽

Matthew R. Greives ◽

Annemarie O’Connor ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Controlled Trial ◽

Skin Grafts ◽

Wound Therapy ◽

Randomized Controlled ◽

Prospective Randomized Controlled Trial

Download Full-text

The use of negative-pressure wound therapy over a cultured epithelial autograft for full-thickness wounds secondary to purpura fulminans in an infant

Archives of Plastic Surgery ◽

10.5999/aps.2020.01032 ◽

2020 ◽

Author(s):

Benjamin Kah Liang Goh ◽

Alvin Wen Choong Chua ◽

Khong Yik Chew ◽

Gavin Chun-Wui Kang ◽

Li-Wei Chiang ◽

...

Keyword(s):

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Purpura Fulminans ◽

Full Thickness ◽

Wound Therapy ◽

Cultured Epithelial Autograft

Download Full-text

An Alternative Treatment Strategy for Complicated Chronic Wounds: Negative Pressure Therapy over Mesh Skin Graft

BioMed Research International ◽

10.1155/2017/8395219 ◽

2017 ◽

Vol 2017 ◽

pp. 1-7 ◽

Cited By ~ 9

Author(s):

Michele Maruccia ◽

Maria G. Onesti ◽

Valentina Sorvillo ◽

Antonio Albano ◽

Luca A. Dessy ◽

...

Keyword(s):

Skin Graft ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Tissue Growth ◽

Real Problem ◽

Skin Defect ◽

Skin Grafts ◽

Wound Therapy ◽

Pressure Therapy ◽

Mesh Skin Graft

Extensive skin defect represents a real problem and major challenge in plastic and reconstructive surgery. On one hand, skin grafts offer a practical method to deal with skin defects despite their unsuitability for several complicated wounds. On the other hand, negative pressure wound therapy (NPWT), applied before skin grafting, promotes granulation tissue growth. The aim of the study is to evaluate the improvement in wound healing given by the merger of these two different approaches. We treated 23 patients for large wounds of multiple factors. Of these, 15 were treated with the application of V.A.C.® Therapy (KCI Medical S.r.l., Milan, Italy), in combination with skin grafts after a prior unsuccessful treatment of 4 weeks with mesh skin grafts and dressings. Another 8 were treated with only mesh skin graft. Pain reduction and wound area reduction were found statistically significant (p<0.0009,p<0.0001). Infection was resolved in almost all patients. According to our study, the use of the negative pressure wound therapy over mesh skin grafts is significantly effective especially in wounds resistant to conventional therapies, thereby improving the rate of skin graft take.

Download Full-text

A retrospective analysis of securing autologous split-thickness skin grafts with negative pressure wound therapy in paediatric burn patients

Burns ◽

10.1016/j.burns.2013.12.007 ◽

2014 ◽

Vol 40 (6) ◽

pp. 1116-1120 ◽

Cited By ~ 16

Author(s):

Michael Hoeller ◽

Michael Valentin Schintler ◽

Klaus Pfurtscheller ◽

Lars-Peter Kamolz ◽

Norbert Tripolt ◽

...

Keyword(s):

Retrospective Analysis ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Burn Patients ◽

Skin Grafts ◽

Wound Therapy ◽

Thickness Skin

Download Full-text

Clinical outcomes of full thickness skin graft combined with negative pressure wound therapy in diabetes mellitus foot amputee after infection

Foot & Ankle Orthopaedics ◽

10.1177/2473011417s000088 ◽

2017 ◽

Vol 2 (3) ◽

pp. 2473011417S0000

Author(s):

Ji-Yong Ahn

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Skin Graft ◽

Negative Pressure ◽

Negative Pressure Wound Therapy ◽

Full Thickness ◽

Full Thickness Skin Graft ◽

Wound Therapy ◽

Full Thickness Skin ◽

Thickness Skin

Category: Diabetes Introduction/Purpose: Infected diabetes mellitus (DM) foot has been controlled with amputation. After performing the amputation with preserving enough length of the foot due to functional and cosmetic advantages, remaining wounds have been covered with split thickness skin graft (STSG) despite of sacrifice of donor site with pain and scar. We hypothesized outcomes of full thickness skin graft (FTSG) combined with negative pressure wound therapy (NPWT) can be an alternative STSG. The aim of this study was to investigate clinical outcomes of FTSG combined with negative pressure wound therapy in DM foot infection. Methods: This study included 21 patients of infected DM foot (21 feet). There were 20 cases of midfoot and 1 case of hindfoot. We performed the amputation and combined NPWT at a mean age of 51.7 years (37 to 81) with the mean 12 months follow-up between June, 2014, and January, 2016. FTSG was performed after sufficient granulation healing of DM foot amputee. We measured multiple risk factors preoperatively and postoperatively. The wound healing after FTSG was evaluated during the followup. The relationship between outcomes of FTSG and multiple risk factors were evaluated. Results: 20 feet showed complete healing of wound. One foot showed failed wound healing. Mean NPWT number of times before the FTSG were 11. Mean C-reactive protein (CRP) values and Hemoglobin A1C (HbA1C) were 1.24 and 9.21 just before FTSG, respectively. There were no significant correlations between wound healing and risk factors (CRP, HbA1C) (p=0.223, p=0.175). Conclusion: Full thickness skin graft combined with negative pressure wound therapy (NPWT) can be the treatment of choice for the diabetes mellitus foot amputee as an alternative STSG.

Download Full-text