scholarly journals Mechanosensory S-neurons rather than AH-neurons appear to generate a rhythmic motor pattern in guinea-pig distal colon

2004 ◽  
Vol 558 (2) ◽  
pp. 577-596 ◽  
Author(s):  
Nick J. Spencer ◽  
Terence K. Smith
Keyword(s):  
Guinea Pig ◽  
Motor Pattern ◽  
Distal Colon ◽  
Rhythmic Motor ◽  
Rhythmic Motor Pattern

Principles of rhythmic motor pattern generation

1996 ◽  
Vol 76 (3) ◽  
pp. 687-717 ◽  
Author(s):  
E. Marder ◽  
R. L. Calabrese
Keyword(s):  
Motor Pattern ◽  
Pattern Generation ◽  
Rhythmic Movements ◽  
Motor Patterns ◽  
Nervous Systems ◽  
Cellular Processes ◽  
Rhythmic Motor ◽  
Computational Analyses ◽  
Motor Pattern Generation ◽  
Rhythmic Motor Pattern

Rhythmic movements are produced by central pattern-generating networks whose output is shaped by sensory and neuromodulatory inputs to allow the animal to adapt its movements to changing needs. This review discusses cellular, circuit, and computational analyses of the mechanisms underlying the generation of rhythmic movements in both invertebrate and vertebrate nervous systems. Attention is paid to exploring the mechanisms by which synaptic and cellular processes interact to play specific roles in shaping motor patterns and, consequently, movement.

scholarly journals A smooth muscle tone-dependent stretch-activated migrating motor pattern in isolated guinea-pig distal colon

2003 ◽  
Vol 551 (3) ◽  
pp. 955-969 ◽  
Author(s):  
T. K Smith ◽  
G. R Oliver ◽  
G. W Hennig ◽  
D. M O'Shea ◽  
P. V. Berghe ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Guinea Pig ◽  
Muscle Tone ◽  
Motor Pattern ◽  
Distal Colon ◽  
Smooth Muscle Tone

scholarly journals Multiple Types of Control by Identified Interneurons in a Sensory-Activated Rhythmic Motor Pattern

2001 ◽  
Vol 21 (8) ◽  
pp. 2903-2911 ◽  
Author(s):  
György Kemenes ◽  
Kevin Staras ◽  
Paul R. Benjamin
Keyword(s):  
Motor Pattern ◽  
Rhythmic Motor ◽  
Rhythmic Motor Pattern

Pilocarpine-induced motor rhythms in the isolated locust suboesophageal ganglion

1997 ◽  
Vol 200 (16) ◽  
pp. 2197-2207 ◽  
Author(s):  
G F Rast ◽  
P Bräunig
Keyword(s):  
Motor Pattern ◽  
Rhythmic Activity ◽  
Neurosecretory Cells ◽  
Muscarinic Agonist ◽  
Suboesophageal Ganglion ◽  
Muscle Receptor ◽  
Rhythmic Motor ◽  
Motor Nerves ◽  
Rhythmic Motor Pattern

Rhythmic activity was recorded from the mandibular motor nerves after treating isolated locust suboesophageal ganglia with the muscarinic agonist pilocarpine. The rhythmic motor pattern consisted of alternating bursts of activity in the antagonistic mandibular opener and closer motoneurones on each side and was synchronised in contralateral homologues. This pattern closely resembled the activity recorded from mandibular muscles in intact feeding locusts. The chewing frequency, however, was approximately three times higher in intact insects than the frequency of the motor pattern recorded from isolated ganglia. Serotonergic neurosecretory cells showed activity synchronous with the pilocarpine-evoked motor pattern. Similarly, rhythmic activity of the motoneurones innervating the two mandibular muscle receptor organs was synchronised with the mandibular motor pattern.

G Protein Signaling in a Neuronal Network is Necessary for Rhythmic Motor Pattern Production

2003 ◽  
Vol 89 (2) ◽  
pp. 762-772 ◽  
Author(s):  
Stefan Clemens ◽  
Paul S. Katz
Keyword(s):  
G Protein ◽  
Motor Pattern ◽  
Synaptic Strength ◽  
G Protein Signaling ◽  
Guanine Nucleotide ◽  
Protein Signaling ◽  
Rhythmic Motor ◽  
Pattern Production ◽  
Sites Of Action ◽  
Rhythmic Motor Pattern

G protein-coupled receptors are widely recognized as playing important roles in mediating the actions of extrinsic neuromodulatory inputs to motor networks. However, the potential for their direct involvement in rhythmic motor pattern generation has received considerably less attention. Results from this study indicate that G protein signaling appears to be integral to the operation of the central pattern generator (CPG) underlying the escape swim of the mollusk Tritonia diomedea. Blocking G protein signaling in a single CPG neuron, cerebral neuron C2, with intracellular iontophoresis of the guanine nucleotide analogue guanosine 5′- O-(2-thiodiphosphate) (GDP-β-S), prevented the production of the swim motor program. Moreover, tonic activation of G protein signaling in this neuron by iontophoresis of the GTP analogues guanosine 5′- O-(3-thiotriphosphate) (GTP-γ-S) and 5′-guanylyl-imidodiphosphate also inhibited motor pattern production. The possible sites of action of these guanine nucleotide analogues were examined to assess potential mechanisms by which they interfered with motor pattern production. Intracellular iontophoresis of GDP-β-S into C2 did not affect C2 basal synaptic strength. However, it did reduce heterosynaptic facilitation of C2 synapses caused by the dorsal swim interneurons (DSIs), a set of serotonergic swim CPG neurons. In contrast, GTP-γ-S directly enhanced C2 synaptic strength onto DFN, mimicking the neuromodulatory effect of the DSIs. GDP-β-S, but not the GTP analogues, decreased C2 excitability, whereas both GTP analogues, but not GDP-β-S, blocked the ability of DSI stimulation to increase C2 excitability. The decrease in C2 excitability caused by GDP-β-S is not likely to be responsible for the inhibition of the swim motor pattern because decreasing C2 firing rate, by injecting hyperpolarizing current, did not prevent the production of the rhythmic motor pattern. Taken together, these data suggest that G protein signaling is a necessary and integral component of the escape swim CPG in Tritonia and that G protein signaling mediates DSI heterosynaptic facilitation of C2 but may not mediate the DSI-evoked enhancement of C2 excitability.

scholarly journals Precise Temperature Compensation of Phase in a Rhythmic Motor Pattern

PLoS Biology ◽  
2010 ◽  
Vol 8 (8) ◽  
pp. e1000469 ◽  
Author(s):  
Lamont S. Tang ◽  
Marie L. Goeritz ◽  
Jonathan S. Caplan ◽  
Adam L. Taylor ◽  
Mehmet Fisek ◽  
...  
Keyword(s):  
Temperature Compensation ◽  
Motor Pattern ◽  
Rhythmic Motor ◽  
Rhythmic Motor Pattern
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