This paper has two objectives, (1) to examine the effects of spatial resolution, (2) to examine the effects of computational box size, upon turbulence statistics and the amount of drag reduction with and without the control scheme of wall oscillation. Direct numerical simulation (DNS) of the fully developed turbulent channel flow was performed at Reynolds number of 200 based on the wall-shear velocity and the channel half-width by using spectral methods. For the first objective, four different grids were applied to the same computational domain and the biggest impact was observed on the logarithmic law of mean velocity profiles and on the amount of drag reduction with 28.3% for the coarsest mesh and 35.4% for the finest mesh. Other turbulence features such as RMS velocity fluctuations, RMS vorticity fluctuations, and bursting events were either overpredicted or underpredicted through coarse grids. For the second objective, two different minimal channels and one natural full channel were studied and 3% drag reduction difference was observed between the smallest minimal channel of 39.1% and the natural full channel of 36.2%. In the near-wall region, however, the minimal channel flow did not exhibit significant difference in the mean velocity profiles and other lower-order statistics. Finally, from this systematical study, it showed that the accuracy of DNS depends more on the spanwise resolution, and it also confirmed that a minimal channel model is able to catch key structures of turbulence in the near-wall region but is much less expensive.