Fully distributed chirped FBG sensor and application in laser-induced interstitial thermotherapy

Author(s):  
Chenglin Li ◽  
Na Chen ◽  
Zhenyi Chen ◽  
Tingyun Wang
2021 ◽  
Vol 151 (3) ◽  
pp. 429-442
Author(s):  
Clark Chen ◽  
Ian Lee ◽  
Claudio Tatsui ◽  
Theresa Elder ◽  
Andrew E. Sloan

Abstract Introduction Laser Interstitial Thermotherapy (LITT; also known as Stereotactic Laser Ablation or SLA), is a minimally invasive treatment modality that has recently gained prominence in the treatment of malignant primary and metastatic brain tumors and radiation necrosis and studies for treatment of spinal metastasis has recently been reported. Methods Here we provide a brief literature review of the various contemporary uses for LITT and their reported outcomes. Results Historically, the primary indication for LITT has been for the treatment of recurrent glioblastoma (GBM). However, indications have continued to expand and now include gliomas of different grades, brain metastasis (BM), radiation necrosis (RN), other types of brain tumors as well as spine metastasis. LITT is emerging as a safe, reliable, minimally invasive clinical approach, particularly for deep seated, focal malignant brain tumors and radiation necrosis. The role of LITT for treatment of other types of tumors of the brain and for spine tumors appears to be evolving at a small number of centers. While the technology appears to be safe and increasingly utilized, there have been few prospective clinical trials and most published studies combine different pathologies in the same report. Conclusion Well-designed prospective trials will be required to firmly establish the role of LITT in the treatment of lesions of the brain and spine.


2021 ◽  
Vol 11 (1) ◽  
pp. 359
Author(s):  
Sung Tae Kim ◽  
Hyejin Yoon ◽  
Young-Hwan Park ◽  
Seung-Seop Jin ◽  
Soobong Shin ◽  
...  

This paper presents a multi-functional strand capable of introducing prestressing force in prestressed concrete (PSC) girders and sensing their static and dynamic behavior as well. This innovative strand is developed by replacing the core steel wire of the strand used in PSC structures with a carbon fiber-reinforced polymer (CFRP) wire with a built-in optical Fiber Bragg Grating (FBG) sensor. A full-scale girder specimen was fabricated by applying this multi-function strand to check the possibility of tracking the change of prestressing force at each construction stage. Moreover, dynamic data could be secured during dynamic loading tests without installing accelerometers and made it possible to obtain the natural frequencies of the structure. The results verified the capability to effectively manage the prestressing force in the PSC bridge structure by applying the PC strand with a built-in optical sensor known for its outstanding practicability and durability.


2015 ◽  
Vol 08 (05) ◽  
pp. 1550018 ◽  
Author(s):  
Shupeng Liu ◽  
Na Chen ◽  
Fufei Pang ◽  
Zhengyi Chen ◽  
Tingyun Wang

Purpose: This work focused on the investigation the hyperthermia performance of the carbon-coated magnetic particles (CCMPs) in laser-induced hyperthermia. Materials and methods: We prepared CCMPs using the organic carbonization method, and then characterized them with transmission electron microscopy (TEM), ultraviolet-visible (UV-Vis) spectrophotometry, vibrating sample magnetometer (VSM) and X-ray diffraction (XRD). In order to evaluate their performance in hyperthermia, the CCMPs were tested in laser-induced thermal therapy (LITT) experiments, in which we employed a fully distributed fiber Bragg grating (FBG) sensor to profile the tissue's dynamic temperature change under laser irradiation in real time. Results: The sizes of prepared CCMPs were about several micrometers, and the LITT results show that the tissue injected with the CCMPs absorbed more laser energy, and its temperature increased faster than the contrast tissue without CCMPs. Conclusions: The CCMPs may be of great help in hyperthermia applications.


2002 ◽  
Vol 47 (16) ◽  
pp. 2987-2999 ◽  
Author(s):  
Ahmed M Minhaj ◽  
Fabrice Manns ◽  
Peter J Milne ◽  
David B Denham ◽  
Nelson Salas Jr ◽  
...  

1992 ◽  
Vol 7 (1-4) ◽  
pp. 121-126 ◽  
Author(s):  
F. X. Roux ◽  
L. Merienne ◽  
B. Leriche ◽  
S. Lucerna ◽  
B. Turak ◽  
...  

Measurement ◽  
2021 ◽  
Vol 171 ◽  
pp. 108851
Author(s):  
Jun-Yi Guo ◽  
Bin Shi ◽  
Meng-Ya Sun ◽  
Cheng-Cheng Zhang ◽  
Guang-Qing Wei ◽  
...  

2015 ◽  
Vol 23 (4) ◽  
pp. 400-411 ◽  
Author(s):  
Claudio E. Tatsui ◽  
R. Jason Stafford ◽  
Jing Li ◽  
Jonathan N. Sellin ◽  
Behrang Amini ◽  
...  

OBJECT High-grade malignant spinal cord compression is commonly managed with a combination of surgery aimed at removing the epidural tumor, followed by spinal stereotactic radiosurgery (SSRS) aimed at local tumor control. The authors here introduce the use of spinal laser interstitial thermotherapy (SLITT) as an alternative to surgery prior to SSRS. METHODS Patients with a high degree of epidural malignant compression due to radioresistant tumors were selected for study. Visual analog scale (VAS) scores for pain and quality of life were obtained before and within 30 and 60 days after treatment. A laser probe was percutaneously placed in the epidural space. Real-time thermal MRI was used to monitor tissue damage in the region of interest. All patients received postoperative SSRS. The maximum thickness of the epidural tumor was measured, and the degree of epidural spinal cord compression (ESCC) was scored in pre- and postprocedure MRI. RESULTS In the 11 patients eligible for study, the mean VAS score for pain decreased from 6.18 in the preoperative period to 4.27 within 30 days and 2.8 within 60 days after the procedure. A similar VAS interrogating the percentage of quality of life demonstrated improvement from 60% preoperatively to 70% within both 30 and 60 days after treatment. Imaging follow-up 2 months after the procedure demonstrated a significant reduction in the mean thickness of the epidural tumor from 8.82 mm (95% CI 7.38–10.25) before treatment to 6.36 mm (95% CI 4.65–8.07) after SLITT and SSRS (p = 0.0001). The median preoperative ESCC Grade 2 was scored as 4, which was significantly higher than the score of 2 for Grade 1b (p = 0.04) on imaging follow-up 2 months after the procedure. CONCLUTIONS The authors present the first report on an innovative minimally invasive alternative to surgery in the management of spinal metastasis. In their early experience, SLITT has provided local control with low morbidity and improvement in both pain and the quality of life of patients.


Sign in / Sign up

Export Citation Format

Share Document