Poster - Thur Eve - 70: Quantification of tumour dose enhancement at kilo-voltage energies due to the presence of gold nanoparticles during radiation therapy: EGSnrcMP Monte Carlo study

2012 ◽  
Vol 39 (7Part4) ◽  
pp. 4638-4638 ◽  
Author(s):  
A Fleck ◽  
R Jiang ◽  
B Schaly ◽  
P Charland ◽  
Et Osei
2012 ◽  
Vol 35 (2) ◽  
pp. 177-185 ◽  
Author(s):  
Mohammad Taghi Bahreyni Toossi ◽  
Mahdi Ghorbani ◽  
Mohammad Mehrpouyan ◽  
Fateme Akbari ◽  
Leila Sobhkhiz Sabet ◽  
...  

2019 ◽  
Vol 25 (2) ◽  
pp. 87-92
Author(s):  
Amir Ghasemi Jangjoo ◽  
Hosein Ghiasi ◽  
Asghar Mesbahi

Abstract 103Pd seed is being used for prostate brachytherapy. Additionally, the dose enhancement effect of gold nanoparticles (GNP) has been reported in previous studies. The aim of this study was to characterize the dosimetric effect of gold nanoparticles in brachytherapy with a 103Pd source. Two brachytherapy seeds including 103 Pd source was simulated using MCNPX Monte Carlo code. The seeds’ models were validated by comparing the MC with reported results. Then, GNPs (10 nm in diameter) with a concentration of 7mg Au/g were simulated uniformly inside the prostate of a humanoid computational phantom. Additionally, the dose enhancement factor (DEF) of nanoparticles was calculated for both modeled brachytherapy seeds. A good agreement was found between the MC calculated and the reported dosimetric parameters. For both seeds, an average DEF of 23% was obtained in tumor volume for prostate brachytherapy. The application of GNPs in conjunction with 103Pd seed in brachytherapy can enhance the delivered dose to the tumor and consequently leads to better treatment outcome.


2005 ◽  
Vol 32 (8) ◽  
pp. 2455-2463 ◽  
Author(s):  
M. De Felici ◽  
R. Felici ◽  
M. Sanchez del Rio ◽  
C. Ferrero ◽  
T. Bacarian ◽  
...  

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