Vancomycin and Clarithromycin Show Synergy against Mycobacterium abscessus In Vitro
Keyword(s):
ABSTRACT Lung disease caused by Mycobacterium abscessus is increasing, and current clarithromycin-based treatment regimens are only moderately effective. Here, we determined the effect of clarithromycin-vancomycin combination against M. abscessus complex isolates in vitro. Synergy was found with a fractional inhibitory concentration index (FICI) score of ≤0.5 and a 4- to 10-fold decrease in MIC.
2005 ◽
Vol 49
(8)
◽
pp. 3544-3545
◽
2000 ◽
Vol 44
(8)
◽
pp. 2179-2181
◽
2012 ◽
Vol 56
(7)
◽
pp. 3785-3796
◽
2011 ◽
Vol 55
(9)
◽
pp. 4485-4487
◽
2012 ◽
Vol 56
(7)
◽
pp. 3549-3555
◽