scholarly journals Lessons Learned from Probing for Impacts of Triclosan and Triclocarban on Human Microbiomes

mSphere ◽  
2016 ◽  
Vol 1 (3) ◽  
Author(s):  
Rolf U. Halden

ABSTRACT Despite increasing interest in the effects of triclosan and triclocarban on human biology, current knowledge is still limited on the impact of these additives to antimicrobial personal care products on the human microbiome. A carefully designed recent study published in mSphere by Poole and colleagues [A. C. Poole et al., mSphere 1(3):e00056-15, 2016, http://dx.doi.org/10.1128/mSphere.00056-15 ] highlights both the power of novel methodologies for microbiome elucidation and the longstanding challenge of employing small-cohort studies to inform risk assessment for chemicals of ubiquitous use in modern society.

2020 ◽  
Vol 12 (5) ◽  
pp. 1796 ◽  
Author(s):  
Gordana Pavić ◽  
Marijana Hadzima-Nyarko ◽  
Borko Bulajić

Due to increases in the number of inhabitants and their concentrations in densely populated areas, there is a growing need in modern society to be cautious towards the impact of catastrophic natural events. An earthquake is a particularly major example of this. Knowledge of the seismic vulnerability of buildings in Europe and around the world has deepened and expanded over the last 20 years, as a result of the many devastating earthquakes. In this study, a review of seismic risk assessment methods in Croatia was presented with respect to the hazard, exposure, and vulnerability of buildings in the fourth largest city (Osijek) in Croatia. The proposed algorithm for a detailed risk assessment was applied to a database and is currently in its initial stage.


2006 ◽  
Vol 4 (2) ◽  
pp. 57 ◽  
Author(s):  
Lt. Col. Mark Stanovich, USMCR

The last two decades have seen technological innovations that have revolutionized the collection and transfer of information, permitting access to and dissemination of massive amounts of data with unprecedented speed and efficiency. These innovations have been incorporated into virtually every aspect of modern society, from personal communications, to commercial and business processes, to governmental function and military operations. The concept of network-centric warfare (NCW) grew out of these new capabilities and has been a prominent topic in strategic and operational discussions in the US military since the late 1990s.In recent years, the concepts behind NCW have been increasingly applied to emergency response, particularly as responders prepare for an increasingly complex threat spectrum in a post-9/11 world. As emergency responders adopt the technological innovations and organizational concepts that enable network-centric operations, attention should be paid to the lessons learned by the US armed forces in the application of the network-centric approach to war-fighting. Emergency operations centers (EOCs), incident command centers (ICCs), and field personnel will require extensive training and experimentation to sort out the impact of this new technology. They must develop protocols and procedures to leverage maximum advantage, while avoiding the undesirable and damaging effects of that technology improperly applied. Because most emergency response organizations lack the vast training resources of the US military, they must be innovative and adaptable in taking advantage of every opportunity to train their personnel in the assimilation of this new technology.


2018 ◽  
Vol 20 (12) ◽  
pp. 1640-1648 ◽  
Author(s):  
Matthew Nkoom ◽  
Guanghua Lu ◽  
Jianchao Liu

The rationale behind this paper was to review the available data regarding the current knowledge on the levels and trends of pharmaceuticals and personal care products (PPCPs) in Taihu Lake.


2016 ◽  
Vol 69 (5-6) ◽  
pp. 183-188 ◽  
Author(s):  
Cedomirka Stanojevic ◽  
Svetlana Simic ◽  
Dragana Milutinovic

Introduction. Atypical work schedules cause reduced sleep, leading to drowsiness, fatigue, decline of cognitive performance and health problems among the members of the nursing staff. The study was aimed at reviewing current knowledge and attitudes concerning the impact of sleep disorders on health and cognitive functions among the members of the nursing staff. Sleep and Interpersonal Relations in Modern Society. The modern 24-hour society involves more and more employees (health services, police departments, public transport) in non-standard forms of work. In European Union countries, over 50% of the nursing staff work night shifts, while in the United States of America 55% of nursing staff work more than 40 hours a week, and 30-70% of nurses sleep less than six hours before their shift. Cognitive Effects of Sleep Deprivation. Sleep deprivation impairs the performance of tasks that require intensive and prolonged attention which increases the number of errors in patients care, and nurses are subject to increased risk of traffic accidents. Sleep Deprivation and Health Disorders. Sleep deprived members of the nursing staff are at risk of obesity, diabetes, gastrointestinal disorders and cardio?vascular disease. The risk factors for breast cancer are increased by 1.79 times, and there is a significantly higher risk for colorectal carcinoma. Conclusion. Too long or repeated shifts reduce the opportunity for sleep, shorten recovery time in nurses, thus endangering their safety and health as well as the quality of care and patients? safety. Bearing in mind the significance of the problem it is necessary to conduct the surveys of sleep quality and health of nurses in the Republic of Serbia as well in order to tackle this issue which is insufficiently recognized.


2019 ◽  
Vol 22 (2) ◽  
pp. 95-112 ◽  
Author(s):  
Per Anker Jensen ◽  
Theo J.M. van der Voordt

Purpose This paper aims to explore the impact of buildings on the creation of healthy workplaces (HWs) and end users’ physical and mental health and well-being. The paper presents available research on the impact of workplace layout, interior design, indoor climate and “green” offices. It ends with reflections on the main lessons learned, gaps in our current knowledge and suggestions for further research. Design/methodology/approach A literature research has been conducted of all papers in four corporate real estate management and facilities management-oriented journals from 2008 to 2017 that discuss health and well-being and related topics such as satisfaction, productivity and creativity. Findings A conceptual model to analyse impact factors for HWs covers the influence of many different variables. Most papers only discuss a particular influencing factor, mainly plants and indoor climate. Various papers show that the spatial layout, in particular the level of openness and opportunities for communication, concentration and privacy and interior design have an important impact on user satisfaction, perceived productivity support and creativity. These factors may have a positive impact on HWs as well and can also be benefits of HWs. Practical implications The paper identifies, which factors are important to consider for creating HWs and potential benefits of HWs. Originality/value This paper discusses the role of CREM and FM in creating HWs and reflects on the available knowledge, current omissions and the need for transdisciplinary follow-up research.


Author(s):  
Paul R. Stevenson ◽  
Richard L. Haessler ◽  
Alex McNeill ◽  
Mark A. Pyne ◽  
Raymond A. West

Risk-informed inservice inspection (ISI) programs have been in use for over seven years as an alternative to current regulatory requirements in the development and implementation of ISI programs for nuclear plant piping systems. Programs using the Westinghouse Owners Group (WOG) (now known as the Pressurized Water Reactor Owners Group - PWROG) risk-informed ISI methodology have been developed and implemented within the U.S. and several other countries. Additionally, many plants have conducted or are in the process of conducting updates to their risk-informed ISI programs. In the development and implementation of these risk-informed ISI programs and the associated updates to those programs, the following important lessons learned have been identified and are addressed. • Concepts such as “loss of inventory,” which are typically not modeled in a plant’s probabilistic risk assessment (PRA) model for all systems. • The importance of considering operator actions in the identification of consequences associated with a piping failure and the categorization of segments as high safety significant (HSS) or low safety significant (LSS). • The impact that the above considerations have had on the large early release frequency (LERF) and categorization of segments as HSS or LSS. • The importance of automation. • Making the update process more efficient to reduce costs associated with maintaining the risk-informed ISI program. The insights gained are associated with many of the steps in the risk-informed ISI process including: development of the consequences associated with piping failures, categorization of segments, structural element selection and program updates. Many of these lessons learned have impacted the results of the risk-informed ISI programs and have impacted the updates to those programs. This paper summarizes the lessons learned and insights gained from the application of the WOG risk-informed ISI methodology in the U.S., Europe and Asia.


ESC CardioMed ◽  
2018 ◽  
pp. 1085-1090
Author(s):  
Slayman Obeid ◽  
Melroy Miranda ◽  
Thomas F. Lüscher

Coronary artery disease (CAD) has been historically investigated as a metabolic disease focusing on dyslipidaemia and inflammation. The advent of the Human Microbiome Project has introduced the gut microbiota as a new player in the pathogenesis of CAD. Recent studies have shown that ageing and Western diets not only increase our risk of CAD but also affect gut microbiota composition and its interaction with our metabolic homeostasis. This chapter provides a short description of the historical timeline and the potential sources of the microbiome in humans. It aims to summarize and give a brief overview of the current knowledge on the impact of the gut microbiota on metabolism, with particular emphasis on CAD and the potential of influencing the microbiota to protect against CAD.


Author(s):  
Devi Pratami

A project always has risks that can lead to project failure. In the project, a risk analysis is required to provide an evaluation for the project to proceed as planned. In the event of inadequate planning and ineffective control, it will result in irregularities identified as a risk to the project. This study aims to analyze the qualitative risk on Fiber Optic Installaion project in Sukabumi, West Java, Indonesia. In addition, risk assessment is undertaken on project implementation. Assessment of risk using the impact and probability to measure the impact of risk occurrence. The impacts are more detailed by classified by time impact, cost impact, quality impact, safety and security impact, proximity. The result is there are 36 risk that may occur and mostly risks are associaated by quality and safety&security impact.


Sign in / Sign up

Export Citation Format

Share Document