The choice of an oral anticoagulant

1972 ◽  
Vol 10 (7) ◽  
pp. 25-28 ◽  
Keyword(s):  
Myocardial Infarction ◽  
Atrial Fibrillation ◽  
Anticoagulant Therapy ◽  
Cerebral Ischaemia ◽  
Oral Anticoagulant ◽  
Short Term ◽  
Prevention And Treatment ◽  
Transient Cerebral Ischaemia

Some of the indications for anticoagulant therapy remain controversial, but they are widely used for the prevention and treatment of thrombosis and embolism after surgery1 and after myocardial infarction,2 in patients with atrial fibrillation, and in those with transient cerebral ischaemia.3 This article discusses the drugs available for long-term use. Those suitable for immediate and short-term use, heparin and arvin, will be discussed in the next issue.

scholarly journals Clinical and pathogenetic features of myocardial infarction in patients with atrial fibrillation

2020 ◽  
pp. 31-39
Author(s):  
S.Y. Borodashkina ◽  
◽  
K.V. Protasov ◽  
Keyword(s):  
Myocardial Infarction ◽  
Atrial Fibrillation ◽  
Observational Studies ◽  
Risk Group ◽  
Clinical Manifestations ◽  
High Risk Group ◽  
Short Term ◽  
Invasive Treatment ◽  
Long Term Prognosis

Patients with myocardial infarction (MI) and atrial fibrillation (AF), the number of which is progressively increasing every year, make up a high-risk group for both recurrent cardiovascular events and bleeding; they require special attention from clinicians. The literature review provides data on features of pathogenesis and clinical manifestations of MI in patients with AF. The analysis of data on AF effect observational studies on short-term and long-term prognosis in patients with myocardial infarction was carried out. Mechanisms of occurrence, clinical features and prognostic value of postinfarction AF are considered. From the standpoint of modern clinical guidelines, information is presented on features of MI invasive treatment in combination with AF. Algorithms of anticoagulant and antiarrhythmic therapy in patients of this category are considered.

scholarly journals Mechanical thrombextraction in patient with acute ischemic stroke on background of oral anticoagulant therapy

2021 ◽  
pp. 36-40
Author(s):  
V.О. Yarosh ◽  
◽  
V.V. Babenko ◽  
O.E. Svyrydiuk ◽  
O.J. Zharinov ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Ischemic Stroke ◽  
Thrombolytic Therapy ◽  
Acute Ischemic Stroke ◽  
Anticoagulant Therapy ◽  
Oral Anticoagulant ◽  
Oral Anticoagulant Therapy ◽  
Interventional Treatment ◽  
Key Words Ischemic Stroke

Thrombolytic therapy, which is a priority treatment strategy in patients with acute ischemic stroke in the first 3-4.5 hours after start of the disease, has significant limitations in case of background anticoagulant therapy. Mechanic thrombextraction is considered to be an alternative therapeutic strategy in case of inefficacy or contraindications to thrombolytic therapy. The article presents a clinical case of the 75-year old female patient with acute cardioembolic stroke on background of heart failure and atrial fibrillation. Long-term background usage of the direct oral anticoagulant due to atrial fibrillation is a limitation to use thrombolytic therapy, therefore mechanical thrombextraction was performed. The case presents possibilities of the successful interventional treatment of acute cardioembolic ischemic stroke. An example of a possible drug-drug interaction possibly leading to reduction of the effectiveness of anticoagulant therapy is shown. Key words: ischemic stroke, anticoagulants, mechanical trombextraction.

Oral Anticoagulant Therapy and its Control: Marcumar (Phenprocoumon), a new highly active Anticoagulant and Konakion (Phytomenadione), as an Effective Regulator

1959 ◽  
Vol 03 (02) ◽  
pp. 271-278 ◽  
Author(s):  
Charles E Brambel ◽  
G Lawrence Serra
Keyword(s):  
Anticoagulant Therapy ◽  
Oral Anticoagulant ◽  
Oral Anticoagulant Therapy ◽  
Term Treatment ◽  
Short Term ◽  
Highly Active ◽  
Long Term Treatment

SummaryData are presented to demonstrate the advantages of Marcumar in short-term and long-term treatment, over less active anticoagulants, and the effectiveness of Konakion as regulator of such therapy.

Long-Term Oral Anticoagulant Therapy in Patients With Unstable Angina or Suspected Non–Q-Wave Myocardial Infarction

Circulation ◽  
1998 ◽  
Vol 98 (11) ◽  
pp. 1064-1070 ◽  
Author(s):  
Sonia S. Anand ◽  
Salim Yusuf ◽  
Janice Pogue ◽  
Jeffrey I. Weitz ◽  
Marcus Flather
Keyword(s):  
Myocardial Infarction ◽  
Unstable Angina ◽  
Anticoagulant Therapy ◽  
Oral Anticoagulant ◽  
Oral Anticoagulant Therapy ◽  
Q Wave
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