scholarly journals EPV234/#208 Outcome after loop electrosurgical excision procedure for cervical high-grade squamous intraepithelial lesion

2021 ◽  
Author(s):  
ST Kwok ◽  
SF Ngu ◽  
KLK Chan ◽  
KY Tse ◽  
MYM Chu ◽  
...  
Keyword(s):  
High Grade ◽  
Squamous Intraepithelial Lesion ◽  
Intraepithelial Lesion ◽  
Loop Electrosurgical Excision ◽  
Loop Electrosurgical Excision Procedure

scholarly journals Comparison of Monopolar Electrosurgical Conization and the Loop Electrosurgical Excision Procedure in the Management of High-Grade Squamous Intraepithelial Lesion

2021 ◽  
Vol 8 ◽  
Author(s):  
Jun Ding ◽  
Haiou Xu ◽  
Lihua Xia ◽  
Shanshan Cao ◽  
Qing Wu
Keyword(s):  
Burn Injury ◽  
High Grade ◽  
Squamous Intraepithelial Lesion ◽  
Abnormal Cervical Cytology ◽  
Significant Difference ◽  
The Status ◽  
Intraepithelial Lesion ◽  
Loop Electrosurgical Excision ◽  
Loop Electrosurgical Excision Procedure ◽  
Cervical Conization

Objectives: To compare the performance and outcomes of monopolar electrosurgical conization (MESC) or the loop electrosurgical excision procedure (LEEP) in the treatment of high-grade squamous intraepithelial lesion (HSIL).Methods: This retrospective study included 554 patients diagnosed with HSIL through biopsy. The study used either LEEP or MESC for cervical conization. Additionally, the medical records of these patients, including the basic information, status of the excision margin, cone depth, cone width, fragmentation, complication, and the results of a 6-month follow-up after conization, were reviewed.Results: Compared to MESC, LEEP had a significantly higher rate of positive endocervical margin (3.77 vs. 8.65%; p = 0.018), burn injury of the margin (4.90 vs. 10.38%; p = 0.016) and a lower rate of adequate cone depth (83.40 vs. 89.62%; p = 0.034). In addition, LEEP was significantly more likely to cause fragmentation (p = 0.000). There was, however, no significant difference in the rate of abnormal cervical cytology and positive high-risk HPV (hrHPV) between these two groups, 6 months after cervical conization.Conclusion: Both LEEP and MESC appeared to be equally effective in the clinical treatment of HSIL. Nonetheless, MESC resulted in a better pathological outcome with regard to the status of the margin, tissue fragmentation, and cone depth.

Outcomes of loop electrosurgical excision procedure for cervical neoplasia in human immunodeficiency virus–infected women

2006 ◽  
Vol 16 (3) ◽  
pp. 1082-1088
Author(s):  
C. Kietpeerakool ◽  
J. Srisomboon ◽  
P. Suprasert ◽  
C. Phongnarisorn ◽  
K. Charoenkwan ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Antiretroviral Therapy ◽  
Pap Smear ◽  
Cervical Neoplasia ◽  
Low Grade ◽  
Squamous Intraepithelial Lesion ◽  
Immunodeficiency Virus ◽  
Intraepithelial Lesion ◽  
Loop Electrosurgical Excision ◽  
Loop Electrosurgical Excision Procedure

The objective of this study was to evaluate the treatment outcomes and complications in human immunodeficiency virus (HIV)–infected women undergoing loop electrosurgical excision procedure (LEEP) for cervical neoplasia. The medical record of 60 evaluable HIV-infected women who had abnormal Papanicolaou (Pap) smear and underwent LEEP following colposcopy at Chiang Mai University Hospital between May 1998 and June 2004 was reviewed. Thirty-one (51.7%) had associated genital infection at screening. Twenty-five (41.7%) had opportunistic infection, but only 18 (30.0%) were treated with antiretroviral therapy. The most common abnormal Pap smear was high-grade squamous intraepithelial lesion (46.7%), followed by low-grade squamous intraepithelial lesion (40.0%). Forty (66.7%) women had clear surgical margins after LEEP. Only one (1.7%) woman had severe intraoperative hemorrhage. Early and late postoperative hemorrhage were noted in three (5%) women of each period. Localized infection of the cervix was detected in seven (11.7%) women. Two (3.3%) women developed cervical stenosis at 6 months after LEEP. There was no significant difference in overall complications between HIV-infected women and the control group (P = 0.24). Among 60 HIV-infected women, no statistical difference in the rate of margins involvement (P = 1.00) and complications (P = 0.85) could be demonstrated between HIV-infected women who received antiretroviral therapy and those who did not. Disease-free rate at 6 and 12 months were 97.1% and 88%, respectively. These data demonstrated that LEEP appears to be safe and effective in HIV-infected women.

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