Measurement of Oral Calcium Absorption from the Gut by External Isotope Counting

1971 ◽  
Vol 57 (2) ◽  
pp. 88-91
Author(s):  
Murdoch A. Macleod
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Calcium Metabolism ◽  
Calcium Absorption ◽  
Normal Subjects ◽  
Intestinal Calcium Absorption ◽  
Calcium Balance ◽  
Oral Calcium ◽  
Absorption Current ◽  
Reliable Methods

AbstractAmong the factors which regulate normal gastro-intestinal calcium absorption, current thought recognises calcium intake, vitamin D and parathyroid hormone as playing an important part. It is well documented that gastro-intestinal calcium absorption is reduced in states of malabsorption, hypoparathyroidism and in patients with chronic renal failure, and raised in states of hyperparathyroidism, urolithiasis and idiopathic hypercalcuria.Difficulties inherent in classic calcium-balance techniques have prompted a search for more practical and reliable methods of measuring the degree of impairment of calcium absorption. This paper describes a study of intestinal calcium absorption in 10 normal subjects and four patients, with various disorders of calcium metabolism, using an external radio-isotope counting technique.

scholarly journals Intestinal Calcium Absorption and Serum Vitamin D Metabolites in Normal Subjects and Osteoporotic Patients

1979 ◽  
Vol 64 (3) ◽  
pp. 729-736 ◽  
Author(s):  
J. C. Gallagher ◽  
B. Lawrence Riggs ◽  
John Eisman ◽  
Alan Hamstra ◽  
Sara B. Arnaud ◽  
...  
Keyword(s):  
Vitamin D ◽  
Calcium Absorption ◽  
Serum Vitamin ◽  
Normal Subjects ◽  
Intestinal Calcium Absorption ◽  
Vitamin D Metabolites ◽  
Serum Vitamin D

Comparison of Dihydrotachysterol and 5,6-trans Vitamin D3 on Intestinal Calcium Absorption in Patients with Chronic Renal Failure

1974 ◽  
Vol 52 (2) ◽  
pp. 272-274 ◽  
Author(s):  
R. Gagnon ◽  
G. W. Ogden ◽  
G. Just ◽  
M. Kaye
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Vitamin D3 ◽  
Calcium Absorption ◽  
Intestinal Calcium Absorption ◽  
Vitamin D Analogue

The effect of dihydrotachysterol2 and of 5,6-trans vitamin D3 on calcium absorption in patients with severe chronic renal failure were compared. Dihydrotachysterol appeared to be more effective than the vitamin D analogue.

Calcium Metabolism during Lactation: Enhanced Intestinal Calcium Absorption in Vitamin D-Deprived, Hypocalcemic Rats*

Endocrinology ◽  
1981 ◽  
Vol 109 (3) ◽  
pp. 900-907 ◽  
Author(s):  
AGNA BOASS ◽  
SVEIN U. TOVERUD ◽  
J. WESLEY PIKE ◽  
MARK R. HAUSSLER
Keyword(s):  
Vitamin D ◽  
Calcium Metabolism ◽  
Calcium Absorption ◽  
Intestinal Calcium Absorption

OCCULT MALABSORPTION CAUSING OSTEITIS FIBROSA CYSTICA

1962 ◽  
Vol 40 (4) ◽  
pp. 481-492
Author(s):  
J. G. Devlin ◽  
D. K. O'Donovan
Keyword(s):  
Vitamin D ◽  
Iron Absorption ◽  
Calcium Absorption ◽  
Calcium Balance ◽  
Gluten Free ◽  
Osteitis Fibrosa Cystica ◽  
Mucosal Atrophy ◽  
Cystic Changes ◽  
Calcium Malabsorption ◽  
Radiological Examinations

ABSTRACT A case is reported of intermittent hypercalcaemia, hypophosphataemia and severe skeletal rarefaction with cystic changes. An occult calcium malabsorption was found. Fat, triolein and iron absorption and radiological examinations were normal. There was gross intestinal mucosal atrophy. She was shown to be in a state of negative calcium balance and this was reversed by vitamin D. A gluten-free diet also improved calcium absorption. It is postulated that the patient had severe secondary hyperparathyroidism as the skeleton reverted to normal after six months of medical treatment.

Critical appraisal of oral calcium load test for indirect assessment of intestinal calcium absorption

Urology ◽  
1979 ◽  
Vol 14 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Kashayar Sakhaee ◽  
Roy Peterson ◽  
Cheryl Northcutt ◽  
Charles Y.C. Pak
Keyword(s):  
Critical Appraisal ◽  
Calcium Absorption ◽  
Intestinal Calcium Absorption ◽  
Load Test ◽  
Oral Calcium ◽  
Indirect Assessment ◽  
Calcium Load

Action of 1,25-dihydroxyvitamin D3 and a diphosphonate on calcium metabolism in rats

1975 ◽  
Vol 229 (2) ◽  
pp. 402-408 ◽  
Author(s):  
JP Bonjour ◽  
U Trechsel ◽  
H Fleisch ◽  
R Schenk ◽  
HF DeLuca ◽  
...  
Keyword(s):  
Calcium Metabolism ◽  
Calcium Absorption ◽  
Bone Mineralization ◽  
Concomitant Administration ◽  
Urinary Calcium ◽  
Intestinal Calcium Absorption ◽  
Bone Morphology ◽  
Dihydroxyvitamin D3 ◽  
Calcium Retention ◽  
Endogenous Production

The effect of 1,25-dihydroxycholecalciferol (1,25-(OH)2D3) on Ca balance, 45Ca kinetics, and bone morphology has been studied in control rats and rats given disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP), 10 mg P/kg sc per day. This large dose of EHDP is known to inhibit bone mineralization and intestinal calcium absorption and to depress the endogenous production of 1,25-(OH)2D3. In conctrol rats, 1,25-(OH)2D3 increased intestinal calcium absorption. However, in contrast to the enhanced calcium absorption that results from an augmentation of dietary calcium, the 1,25(OH)2D3-induced augmentation of calcium absorption does not lead to a rise in calcium retention, the intestinal effect being matched by an increased excretion of urinary calcium. The EHDP-induced decrease of intestinal calcium absorption could be completely prevented by the concomitant administration of 1,25-(OH)2D3 but not the inhibition of bone mineralization. Therefore, in contrast to the impairment of calcium absorption, that of bone mineralization brought about by large doses of EHDP cannot be merely attributed to a decreased production of 1,25-(OH)2D3.

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