Inhalation with NDS27 attenuates pulmonary neutrophilic inflammation in recurrent airway obstruction

2011 ◽  
Vol 169 (4) ◽  
pp. 101-101 ◽  
Author(s):  
C. Sandersen ◽  
D. Olejnik ◽  
T. Franck ◽  
P. Neven ◽  
D. Serteyn ◽  
...  
Keyword(s):  
Airway Obstruction ◽  
Recurrent Airway Obstruction ◽  
Neutrophilic Inflammation

scholarly journals Equine Recurrent Airway Obstruction

2014 ◽  
Vol 37 (2) ◽  
pp. 115-120 ◽  
Author(s):  
Artur Niedźwiedź
Keyword(s):  
Pulmonary Function ◽  
Airway Obstruction ◽  
Environmental Changes ◽  
Clinical Signs ◽  
Dust Exposure ◽  
Common Disease ◽  
Recurrent Airway Obstruction ◽  
Organic Dust ◽  
Mucus Production ◽  
Neutrophilic Inflammation

AbstractEquine Recurrent Airway Obstruction (RAO), also known as heaves or broken wind, is one of the most common disease in middle-aged horses. Inflammation of the airway is inducted by organic dust exposure. This disease is characterized by neutrophilic inflammation, bronchospasm, excessive mucus production and pathologic changes in the bronchiolar walls. Clinical signs are resolved in 3-4 weeks after environmental changes. Horses suffering from RAO are susceptible to allergens throughout their lives, therefore they should be properly managed. In therapy the most importanthing is to eliminate dust exposure, administration of corticosteroids and use bronchodilators to improve pulmonary function.

scholarly journals Evidence for endothelin‐B receptor involvement in recurrent airway obstruction in horses

2006 ◽  
Vol 20 (4) ◽  
Author(s):  
Changaram Venugopal ◽  
Sumanth Polikepahad ◽  
Earnestine Holmes ◽  
Rustin M. Moore
Keyword(s):  
Airway Obstruction ◽  
Recurrent Airway Obstruction ◽  
Endothelin B Receptor ◽  
Endothelin B

scholarly journals Participation of Treg cells in equine Recurrent Airway Obstruction

2013 ◽  
Vol 4 ◽  
Author(s):  
Henriquez Claudio ◽  
Moran Gabriel ◽  
Perez Barbara ◽  
Morales Natalia ◽  
Folch Hugo
Keyword(s):  
Airway Obstruction ◽  
Treg Cells ◽  
Recurrent Airway Obstruction

scholarly journals In an Adult Horse With Severe Asthma (Previously Recurrent Airway Obstruction) Does Using Inhaled Corticosteroids Result in an Equal Improvement in Clinical Signs When Compared to Systemic Corticosteroids?

2018 ◽  
Vol 3 (2) ◽  
Author(s):  
Natasha A Jocelyn
Keyword(s):  
Open Access ◽  
Airway Obstruction ◽  
Severe Asthma ◽  
Inhaled Corticosteroids ◽  
Clinical Signs ◽  
The Body ◽  
Recurrent Airway Obstruction ◽  
Bottom Line ◽  
Systemic Corticosteroids ◽  
Equine Asthma

<strong>PICO question</strong><br /><p>In an adult horse with severe asthma (previously recurrent airway obstruction (RAO)) does using inhaled corticosteroids result in an equal improvement in clinical signs when compared to systemic corticosteroids?</p><strong>Clinical bottom line</strong><br /><p>The level of confidence in the outcomes from the body of evidence in the 4 papers identified is high. This suggests inhaled corticosteroids (fluticasone and beclomethasone) when used at an appropriate dose can have equivalent effects on severe equine asthma as systemic intravenous dexamethasone. Inhaled corticosteroids can take longer to have the desired effects. </p><br /> <img src="https://www.veterinaryevidence.org/rcvskmod/icons/oa-icon.jpg" alt="Open Access" /> <img src="https://www.veterinaryevidence.org/rcvskmod/icons/pr-icon.jpg" alt="Peer Reviewed" />

scholarly journals Epithelial expression of mRNA and protein for IL-6, IL-10 and TNF-α in endobronchial biopsies in horses with recurrent airway obstruction

2008 ◽  
Vol 4 (1) ◽  
pp. 8 ◽  
Author(s):  
Miia Riihimäki ◽  
Amanda Raine ◽  
Jamshid Pourazar ◽  
Thomas Sandström ◽  
Tatiana Art ◽  
...  
Keyword(s):  
Airway Obstruction ◽  
Recurrent Airway Obstruction ◽  
Tnf Α
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