Active and passive Ca movements in dog red blood cells and resealed ghosts
1979 ◽
Vol 237
(1)
◽
pp. C10-C16
◽
Keyword(s):
Low Ph
◽
Dog red blood cells accumulate Ca rapidly when deprived of substrate or cooled to 5 degrees C. The latter effect is reversible as the cells are rewarmed to body temperature. Resealed ghosts extrude Ca, provided ATP is incorporated in them. Passive fluxes of Ca are stimulated by Na on the opposite side of the membrane, consistent with a model for Ca-Na countertransport. Quinidine, cell shrinkage, and low pH--all known to suppress net Ca influx--have no accelerating effect on Ca efflux, thus validating earlier conclusions about the variability of the coupling ratio for Ca-Na exchange. The significance of these findings for cell volume regulation is discussed.
1980 ◽
Vol 76
(6)
◽
pp. 683-708
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Keyword(s):
1983 ◽
Vol 82
(6)
◽
pp. 761-784
◽
1977 ◽
Vol 69
(5)
◽
pp. 537-552
◽
2004 ◽
Vol 287
(2)
◽
pp. C336-C344
◽
Keyword(s):
2010 ◽
Vol 298
(3)
◽
pp. C510-C520
◽
1987 ◽
Vol 253
(1)
◽
pp. C60-C65
◽
Keyword(s):
1986 ◽
Vol 250
(3)
◽
pp. C423-C429
◽
Keyword(s):