Renal and extra-renal excretion of calcium in the marine teleost, Gadus morhua

The calcium turnover, with particular emphasis on the routes and rates of excretion, was investigated in the Atlantic cod, Gadus morhua. A very rapid internal redistribution of injected 45Ca was demonstrated, with the decline in the plasma concentration conforming to the power function f(t) = 8.83% X t-0.585. The clearance for 45Ca and [3H]inulin were both linearly correlated to urine flow and showed a ratio (Cca/CIn) of 2.6:1. Likewise a linear correlation between the renal and extra-renal excretion of 45Ca could be demonstrated with a ratio of 1:0.47, indicating that the renal route of excretion is of major importance in this species. The renal excretion of calcium was estimated to be 4.2 mumol X kg-1 X h-1 and the total calcium excretion to be 6.2 mumol X kg-1 X h-1. Calculations are presented, suggesting that the balance between intake and excretion of calcium can be explained in terms of growth of the animal, which would allow for an increase in the amount of body calcium of approximately 5 g X yr-1. It is also concluded that because about two-thirds calcium is excreted via the renal route, the kidneys may be the most important site for the regulation of calcium excretion in the cod.

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Kinetics of Calcium Fluxes Across the Intestinal Mucosa of the Marine Teleost, Gadus Morhua, Measured Using an In Vitro Perfusion Method

Journal of Experimental Biology ◽

10.1242/jeb.140.1.171 ◽

1988 ◽

Vol 140 (1) ◽

pp. 171-186 ◽

Cited By ~ 2

Author(s):

KRISTINA SUNDELL ◽

BJÖRN THRANDUR BJÖRNSSON

Keyword(s):

Intestinal Mucosa ◽

Gadus Morhua ◽

Atlantic Cod ◽

Calcium Influx ◽

Calcium Excretion ◽

Passive Component ◽

Marine Teleost ◽

Atpase Inhibitor

An in vitro technique for perfusion of the intestinal vasculature and lumen was developed and used to measure calcium (Ca2+) fluxes across the intestinal mucosa of the marine teleost, the Atlantic cod (Gadus morhua). Saturable and nonsaturable components of the calcium influx and efflux were determined. The calcium influx had one passive component and one saturable component, following Michaelis-Menten kinetics with Km = 8.41mmoll−1 and Vmax = 0.604μmol Ca2+ kg−1 h−1. At physiological Ca2+ concentrations in the vascular ([Ca2+] = l.9mmoll−1) and luminal ([Ca2+] =14.9mmoll−1) perfusion fluids, the saturable component amounted to 60% of the Ca2+ influx. The high-affinity Ca2+-ATPase inhibitor chlorpromazine (CP, 10−4moll−1) antagonized 45% of the Ca2+ influx. The Ca2+ efflux across the intestinal mucosa of the cod was a saturable process, following Michaelis-Menten kinetics with Km =6.15mmoll−1 and Vmax =3.79μmol Ca2+ kg−1h−1, but insensitive to CP (l0−5moll−1). The Ca2+ efflux was l.22μumol Ca2+ kg−1 h−1, representing about 20% of the total calcium excretion and about 50% of the extrarenal excretion of the Atlantic cod in vivo.

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Effects of vitamin D3, 25(OH) vitamin D3, 24,25(OH)2 vitamin D3, and 1,25(OH)2 vitamin D3 on the in vitro intestinal calcium absorption in the marine teleost, Atlantic cod (Gadus morhua)

General and Comparative Endocrinology ◽

10.1016/0016-6480(90)90049-r ◽

1990 ◽

Vol 78 (1) ◽

pp. 74-79 ◽

Cited By ~ 32

Author(s):

Kristina Sundell ◽

Björn Th. Björnsson

Keyword(s):

Vitamin D3 ◽

Gadus Morhua ◽

Calcium Absorption ◽

Atlantic Cod ◽

Intestinal Calcium Absorption ◽

Marine Teleost

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Purification of hepatic microsomal cytochromes P-450 from β-naphthoflavone-treated Atlantic cod (Gadus morhua), a marine teleost fish

Biochimica et Biophysica Acta (BBA) - General Subjects ◽

10.1016/0304-4165(85)90222-3 ◽

1985 ◽

Vol 840 (3) ◽

pp. 409-417 ◽

Cited By ~ 103

Author(s):

A GOKSOYR

Keyword(s):

Teleost Fish ◽

Gadus Morhua ◽

Atlantic Cod ◽

Marine Teleost ◽

Marine Teleost Fish

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ORGAN DISTRIBUTION OF A HIGH AFFINITY RECEPTOR FOR l,25(OH)2 VITAMIN D3 IN THE ATLANTIC COD (GADUS MORHUA), A MARINE TELEOST

Vitamin D ◽

10.1515/9783110850345-036 ◽

1991 ◽

pp. 114-115

Keyword(s):

Vitamin D3 ◽

Gadus Morhua ◽

Atlantic Cod ◽

Organ Distribution ◽

Marine Teleost ◽

High Affinity ◽

High Affinity Receptor ◽

Affinity Receptor

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Effects of temperature on life history set the sensitivity to fishing in Atlantic cod Gadus morhua

Marine Ecology Progress Series ◽

10.3354/meps10943 ◽

2014 ◽

Vol 514 ◽

pp. 217-229 ◽

Cited By ~ 11

Author(s):

HY Wang ◽

LW Botsford ◽

JW White ◽

MJ Fogarty ◽

F Juanes ◽

...

Keyword(s):

Life History ◽

Gadus Morhua ◽

Atlantic Cod ◽

Effects Of Temperature

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Responses of Atlantic cod Gadus morhua head kidney leukocytes to phytase produced by gastrointestinal-derived bacteria

Fish Physiology and Biochemistry ◽

10.1007/s10695-009-9364-0 ◽

2009 ◽

Vol 36 (4) ◽

pp. 883-891 ◽

Cited By ~ 14

Author(s):

Carlo C. Lazado ◽

Christopher Marlowe A. Caipang ◽

Sanchala Gallage ◽

Monica F. Brinchmann ◽

Viswanath Kiron

Keyword(s):

Gadus Morhua ◽

Atlantic Cod ◽

Head Kidney

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Some recent data on sperm morphology and motility kinetics in Atlantic cod (Gadus morhua L.)

Fish Physiology and Biochemistry ◽

10.1007/s10695-020-00915-4 ◽

2021 ◽

Author(s):

Sayyed Mohammad Hadi Alavi ◽

Azadeh Hatef ◽

Ian A.E. Butts ◽

Olga Bondarenko ◽

Jacky Cosson ◽

...

Keyword(s):

Gadus Morhua ◽

Sperm Morphology ◽

Atlantic Cod

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Natural mortality from poor condition in Atlantic cod (Gadus morhua)

Canadian Journal of Fisheries and Aquatic Sciences ◽

10.1139/f00-023 ◽

2000 ◽

Vol 57 (4) ◽

pp. 826-836 ◽

Cited By ~ 96

Author(s):

Jean-Denis Dutil ◽

Yvan Lambert

Keyword(s):

Gadus Morhua ◽

Atlantic Cod ◽

Negative Impact ◽

Fish Muscle ◽

Early Summer ◽

Wild Fish ◽

Natural Mortality ◽

Muscle Lactate ◽

Lactate Dehydrogenase Activity ◽

Poor Condition

The extent of energy depletion was assessed in Atlantic cod (Gadus morhua) in spring and early summer (1993-1995) to assess relationships between poor condition and natural mortality. Several indices of condition were compared in wild fish in the northern Gulf of St. Lawrence and in fish exposed to a prolonged period of starvation in laboratory experiments. Discriminant analyses classified only a small fraction of the wild fish as similar to cod that did not survive and a much larger fraction as similar to cod that survived starvation. This percentage increased from April to May and peaked in June 1993 and 1994. Condition factor and muscle somatic index allowed a clear distinction between live and dead fish. Muscle lactate dehydrogenase activity suggested that cod had experienced a period of negative growth early in 1993, 1994, and 1995. Fish classified as similar to starved individuals were characterized by a higher gonad to liver mass ratio than others. Reproduction may have a negative impact on survival not only in spring but also later into summer, as some individuals were found not to have recovered by late summer. This study shows that natural mortality from poor condition contributed to lower production in the early 1990s.

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