scholarly journals Efficient, One-Pot Synthesis of Tetrahydrobenzo[a]xanthen-11-ones and Dibenzo[a,j]xanthenes Using Trichloroacetic Acid as a Solid Heterogeneous Catalyst Under Solvent-Free Conditions

2011 ◽  
Vol 8 (4) ◽  
pp. 1895-1899 ◽  
Author(s):  
Zahed Karimi Jaber ◽  
S. Zoleykha Abbasi ◽  
Baharak Pooladian ◽  
Marziyeh Jokar
Keyword(s):  
Heterogeneous Catalyst ◽  
Efficient Method ◽  
Trichloroacetic Acid ◽  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Aryl Aldehydes ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
Free Media

A simple and efficient method have been described for the synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-one derivatives employing a one-pot, three-component reaction of aryl aldehydes, 2-naphthol and dimedone in the presence of trichloroacetic acid under solvent-free conditions. Also the condensation of 2-naphthol with alkyl or aryl aldehydes in the presence of trichloroacetic acid under solvent-free media to afford the corresponding 14-aryl or alkyl -14H-dibenzo [a.j]xanthenes in excellent yields and short reaction times is described.

scholarly journals Efficient Synthesis of 1-Amidoalkyl-2-Naphthols by One-Pot, Three-Component Reaction under Solvent-Free Conditions

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Zahed Karimi-Jaberi ◽  
Marziyeh Jokar ◽  
S. Zoleykha Abbasi
Keyword(s):  
Trichloroacetic Acid ◽  
Reaction Times ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
One Pot Condensation ◽  
High Yields ◽  
Free Media

Two efficient and direct procedures have been developed for the preparation of 1-amidoalkyl-2-naphthols by a one-pot condensation of aldehydes, 2-naphthol, and amides in the presence of trichloroacetic acid or cobalt (II) chloride as catalyst. The reactions were carried out under solvent-free media. High yields, short reaction times, easy workup of the catalyst are advantages of these procedures.

scholarly journals An Efficient and Green Procedure for the Synthesis of 2,4,6-Triarylpyridines Using PPA-SiO2as a Reusable Heterogeneous Catalyst Under Solvent-Free Conditions

2012 ◽  
Vol 9 (4) ◽  
pp. 2037-2043 ◽  
Author(s):  
Abolghasem Davoodnia ◽  
Bahareh Razavi ◽  
Niloofar Tavakoli-Hoseini
Keyword(s):  
Heterogeneous Catalyst ◽  
Simple Procedure ◽  
Substantial Reduction ◽  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
High Yields ◽  
Work Up

Silica gel-supported polyphosphoric acid (PPA-SiO2) was found to be highly efficient, eco-friendly and recyclable heterogeneous catalyst for the synthesis of 2,4,6-triarylpyridines through one-pot three-component reaction of acetophenone, aryl aldehydes, and ammonium acetate under solvent-free conditions. This method has several advantages, such as simple procedure with an easy work-up, short reaction times, and high yields. Furthermore, the catalyst could be recycled after a simple work-up, and used at least three times without substantial reduction in its catalytic activity.

scholarly journals Synthesis of 2,4,6-triarylpyridines Using AlPO4 Under Solvent-free Conditions

2010 ◽  
Vol 2 (2) ◽  
pp. 337-342 ◽  
Author(s):  
P. Rajput ◽  
N. J. P. Subhashini ◽  
Shiva Raj
Keyword(s):  
Heterogeneous Catalyst ◽  
Simple Procedure ◽  
Reaction Times ◽  
Aluminum Phosphate ◽  
Solvent Free ◽  
One Pot ◽  
One Pot Synthesis ◽  
Solvent Free Conditions

A series of 2,4,6-triarylpyridines have been prepared using a variety of aromatic and heteroaromatic aldehydes in the presence of aluminum phosphate (AlPO4) as a heterogeneous catalyst at 120 oC under solvent-free conditions. The present methodology offers several advantages such as excellent yields, simple procedure, shorter reaction times, milder conditions and the catalyst exhibited remarkable reusable activity. Keywords: Aluminum phosphate; 2,4,6-triarylpyridines; One-pot synthesis; Shorter reaction times;  Reusable activity.  © 2010 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. DOI: 10.3329/jsr.v2i2.3859               J. Sci. Res. 2 (2), 337-342 (2010) 

A One-Pot, Three-Component, Solvent-Free Synthesis of Novel 6H-Chromeno[3’,4’:5,6]Pyrido[2,3-d]Pyrimidine-Triones under Microwave Irradiation

2018 ◽  
Vol 42 (12) ◽  
pp. 604-607
Author(s):  
Loghman Firoozpour ◽  
Hoda Yahyavi ◽  
Ramona Ejtemaei ◽  
Setareh Moghimi ◽  
Alireza Foroumadi
Keyword(s):  
Microwave Irradiation ◽  
Efficient Method ◽  
Barbituric Acid ◽  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Substituted Benzaldehydes ◽  
High Yields ◽  
Solvent Free Synthesis

A green and efficient method for preparing novel heterocyclic systems is established through the reaction of differently substituted benzaldehydes, barbituric acid and 4-amino-2H-chromene-2-one under solvent-free conditions. This method affords 6H-chromeno[3’,4’:5,6] pyrido[2,3-d]pyrimidine-trione derivatives in high yields and short reaction times.

Glutamic Acid as an Efficient and Green Catalyst for the One-Pot Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles under Thermal, Solvent-Free Conditions

2017 ◽  
Vol 41 (11) ◽  
pp. 673-675 ◽  
Author(s):  
Fahimeh Khazaee Feizabad ◽  
Khatereh Khandan-Barani ◽  
Alireza Hassanabadi
Keyword(s):  
Glutamic Acid ◽  
Reaction Times ◽  
Catalytic Amount ◽  
Solvent Free ◽  
One Pot ◽  
Green Catalyst ◽  
Aryl Aldehydes ◽  
Solvent Free Conditions ◽  
The One ◽  
Tetrasubstituted Imidazoles

A high-yielding synthesis of 1,2,4,5-tetrasubstituted imidazoles is described, involving the reaction of 1,2-dicarbonyl compounds, aryl aldehydes, amines and ammonium acetate in the presence of a catalytic amount of glutamic acid under thermal, solvent-free conditions. The salient features of this protocol are aerobic conditions, a non-hazardous green catalyst, short reaction times and mild reaction conditions.

ZnO@SnO2 Mixed Metal Oxide as an Efficient and Recoverable Nanocatalyst for the Solvent Free Synthesis of Hantzsch 1,4-Dihydropyridines

2019 ◽  
Vol 16 (2) ◽  
pp. 139-144 ◽  
Author(s):  
Bharatkumar M. Sapkal ◽  
Prakash K. Labhane ◽  
Shamrao T. Disale ◽  
Dhananjay H. More
Keyword(s):  
Metal Oxide ◽  
Metal Oxide Nanoparticles ◽  
Reaction Times ◽  
Solvent Free ◽  
Catalyst Loading ◽  
Mixed Metal Oxide ◽  
One Pot ◽  
Mixed Metal ◽  
Solvent Free Conditions ◽  
Three Component Reaction

An efficient synthesis of Hantzsch 1,4-dihydropyridines via a one-pot three-component reaction of ethyl acetoacetate, substituted aldehydes and ammonium acetate in the presence of ZnO@SnO2 mixed metal oxide nanoparticles under solvent-free conditions has been reported. Compare to the reported reactions, this method shows attractive aspects such as cleaner reaction profile, shorter reaction times, minimum catalyst loading and high yields. Isolated catalysts were reused for new reactions without considerable loss of their catalytic activity.

Copper(ii) oxide nanoparticles as a highly active and reusable heterogeneous catalyst for the construction of phenyl-1H-pyrazolo[3,4-b]pyridine derivatives under solvent-free conditions

RSC Advances ◽  
2016 ◽  
Vol 6 (105) ◽  
pp. 103838-103842 ◽  
Author(s):  
Mudumala Veeranarayana Reddy ◽  
Yeon Tae Jeong
Keyword(s):  
Efficient Method ◽  
Reaction Times ◽  
Solvent Free ◽  
Oxide Nanoparticles ◽  
Pyridine Derivatives ◽  
One Pot ◽  
Cuo Nps ◽  
Highly Active ◽  
Solvent Free Conditions ◽  
The One

We developed a simple and efficient method for the one-pot synthesis of phenyl-1H-pyrazolo[3,4-b]pyridine derivatives in the presence of CuO NPs under solvent-free conditions with higher yields and shorter reaction times.

scholarly journals One-pot multicomponent nitro-Mannich reaction using a heterogeneous catalyst under solvent-free conditions

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e5065 ◽  
Author(s):  
Giovanna Bosica ◽  
Ramon Zammit
Keyword(s):  
Heterogeneous Catalyst ◽  
Mannich Reaction ◽  
Reaction Times ◽  
Solvent Free ◽  
Free Medium ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Activity Loss ◽  
A Minor ◽  
Minor Activity

An environmentally-friendly, one-pot multicomponent reaction of various aldehydes, amines and nitroalkanes for the synthesis of β-nitroamines is here described. Amberlyst A-21 supported CuI was found to be a highly efficient novel heterogeneous catalyst for the three-component nitro-Mannich reaction between aldehydes, amines and nitroalkanes. The developed protocol is performed in a solvent-free medium to produce a variety of β-nitroamines in good to excellent yields within short reaction times. The catalyst can be easily prepared and recovered. It has been tested up to eight times with only a minor activity loss.

A one-pot three-component synthesis of novel α-sulfamidophosphonates under ultrasound irradiation and catalyst-free conditions

RSC Advances ◽  
2015 ◽  
Vol 5 (49) ◽  
pp. 39324-39329 ◽  
Author(s):  
Billel Belhani ◽  
Malika Berredjem ◽  
Marc Le Borgne ◽  
Zouhair Bouaziz ◽  
Jacques Lebreton ◽  
...  
Keyword(s):  
Reaction Times ◽  
Ultrasound Irradiation ◽  
Solvent Free ◽  
One Pot ◽  
Mild Conditions ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
Work Up

A one-pot synthesis of novel α-sulfamidophosphonates is described via a three-component reaction under ultrasound irradiation, catalyst-free and solvent-free conditions. The synthesis has mild conditions, short reaction times, good yields and simple work-up procedures.

scholarly journals Three-component reaction of β-keto esters, aromatic aldehydes and urea/thiourea promoted by caffeine, a green and natural, biodegradable catalyst for eco-safe Biginelli synthesis of 3,4-dihydropyrimidin-2(1H)-ones/thiones derivatives under solvent-free conditions

2018 ◽  
Vol 83 (6) ◽  
pp. 673-684 ◽  
Author(s):  
Farzaneh Mohamadpour ◽  
Mojtaba Lashkari
Keyword(s):  
Biginelli Reaction ◽  
Reaction Times ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
Solid Catalyst ◽  
One Pot ◽  
Keto Esters ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
High Yields

Caffeine was found to be a natural and green and biodegradable catalyst for the one-pot, three-component condensation Biginelli reaction of ?-keto esters, aromatic aldehydes and urea/thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones/thiones derivatives under solvent-free conditions. The remarkable features of this green procedure are high yields, short reaction times, simplicity of operation and work-up procedures, the availability and easy handling of this solid catalyst, avoidance of hazardous or toxic catalysts and organic solvents and economic availability of the catalyst.

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