scholarly journals An Unusual Case of a Tonsillolith

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
John Chan ◽  
Mamun Rashid ◽  
Yakubu Karagama
Keyword(s):  
Risk Factors ◽  
Foreign Body ◽  
Computer Tomography ◽  
Unusual Case ◽  
Fish Bone ◽  
Plain Radiography ◽  
History Taking ◽  
Digital Palpation ◽  
Wide Range ◽  
History Of

Tonsilloliths are rare calcified concretions that develop in tonsillar crypts within the substance of the tonsil or around it. Large tonsilloliths can mimic many conditions including abscesses or neoplasms. Given the wide range of differentials, it is difficult to diagnose tonsilloliths unless there is a considered emphasis on thorough history taking, careful inspection and a detailed characterisation of the lesion through digital palpation. This may be further supplemented with investigations such as plain radiography and computer tomography. Here, we illustrate a case with risk factors of oropharyngeal cancer and a history of fish bone impaction in the throat that was initially diagnosed as a “tonsillar foreign body” which turned out eventually to be a large tonsillolith.

scholarly journals A case report: spontaneous postpartum rupture of unscarred uterus

2018 ◽  
Vol 7 (8) ◽  
pp. 3420
Author(s):  
Swati Singh ◽  
Ravinder Ahlawat
Keyword(s):  
Risk Factors ◽  
Differential Diagnosis ◽  
Unusual Case ◽  
Surgical Intervention ◽  
Emergency Laparotomy ◽  
Full Thickness ◽  
Uterine Incision ◽  
History Of ◽  
Rupture Of Uterus ◽  
Specific Symptoms

Rupture of uterus is characterized by a breach in the wall of the uterus involving its full thickness. An unscarred uterus rupture is uncommon. It has non-specific symptoms and presentation differs according to site and time of rupture. Authors report an unusual case of spontaneous rupture of unscarred uterus. A 32-year-old, pregnant woman, developed postpartum bleeding with no history of prior uterine incision. She was diagnosed as a case of rupture of uterus and emergency laparotomy was done. Early diagnosis and immediate surgical intervention may significantly improve the prognosis. Differential diagnosis of uterine rupture should always be kept in mind in all patients with or without risk factors.

A population-based twin study in women of smoking initiation and nicotine dependence

1999 ◽  
Vol 29 (2) ◽  
pp. 299-308 ◽  
Author(s):  
K. S. KENDLER ◽  
M. C. NEALE ◽  
P. SULLIVAN ◽  
L. A. COREY ◽  
C. O. GARDNER ◽  
...  
Keyword(s):  
Risk Factors ◽  
Nicotine Dependence ◽  
Structural Equation ◽  
Substance Dependence ◽  
Smoking Initiation ◽  
Population Based ◽  
Familial Factors ◽  
Wide Range ◽  
History Of ◽  
Low Levels

Background. The development of drug dependence requires prior initiation. What is the relationship between the risk factors for initiation and dependence?Methods. Using smoking as a model addiction, we assessed smoking initiation (SI) and nicotine dependence (ND) by personal interview in 1898 female twins from the population-based Virginia Twin Registry. We developed a twin structural equation model that estimates the correlation between the liability to SI and the liability to ND, given SI.Results. The liabilities to SI and ND were substantially correlated but not identical. Heritable factors played an important aetiological role in SI and in ND. While the majority of genetic risk factors for ND were shared with SI, a distinct set of familial factors, which were probably partly genetic, solely influenced the risk for ND. SI was associated with low levels of education and religiosity, high levels of neuroticism and extroversion and a history of a wide range of psychiatric disorders. ND was associated with low levels of education, extroversion, mastery, and self-esteem, high levels of neuroticism and dependency and a history of mood and alcohol use disorders.Conclusions. The aetiological factors that influence SI and ND, while overlapping, are not perfectly correlated. One set of genetic factors plays a significant aetiological role in both SI and ND, while another set of familial factors, probably in part genetic, solely influences ND. Some risk factors for SI and ND impact similarly on both stages, some act at only one stage and others impact differently and even in opposite directions at the two stages. The pathway to substance dependence is complex and involves multiple genetic and environmental risk factors.

scholarly journals A logistic regression analysis of risk factors in ME/CFS pathogenesis

BMC Neurology ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Eliana M. Lacerda ◽  
Keith Geraghty ◽  
Caroline C. Kingdon ◽  
Luigi Palla ◽  
Luis Nacul
Keyword(s):  
Risk Factors ◽  
Multiple Sclerosis ◽  
Regression Analysis ◽  
Risk Factor ◽  
Family History ◽  
Disease Onset ◽  
Healthy Controls ◽  
Lower Income ◽  
Wide Range ◽  
History Of

Abstract Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex disease, whose exact cause remains unclear. A wide range of risk factors has been proposed that helps understanding potential disease pathogenesis. However, there is little consistency for many risk factor associations, thus we undertook an exploratory study of risk factors using data from the UK ME/CFS Biobank participants. We report on risk factor associations in ME/CFS compared with multiple sclerosis participants and healthy controls. Methods This was a cross-sectional study of 269 people with ME/CFS, including 214 with mild/moderate and 55 with severe symptoms, 74 people with multiple sclerosis (MS), and 134 healthy controls, who were recruited from primary and secondary health services. Data were collected from participants using a standardised written questionnaire. Data analyses consisted of univariate and multivariable regression analysis (by levels of proximity to disease onset). Results A history of frequent colds (OR = 8.26, P <= 0.001) and infections (OR = 25.5, P = 0.015) before onset were the strongest factors associated with a higher risk of ME/CFS compared to healthy controls. Being single (OR = 4.41, P <= 0.001), having lower income (OR = 3.71, P <= 0.001), and a family history of anxiety is associated with a higher risk of ME/CFS compared to healthy controls only (OR = 3.77, P < 0.001). History of frequent colds (OR = 6.31, P < 0.001) and infections before disease onset (OR = 5.12, P = 0.005), being single (OR = 3.66, P = 0.003) and having lower income (OR = 3.48, P = 0.001), are associated with a higher risk of ME/CFS than MS. Severe ME/CFS cases were associated with lower age of ME/CFS onset (OR = 0.63, P = 0.022) and a family history of neurological illness (OR = 6.1, P = 0.001). Conclusions Notable differences in risk profiles were found between ME/CFS and healthy controls, ME/CFS and MS, and mild-moderate and severe ME/CFS. However, we found some commensurate overlap in risk associations between all cohorts. The most notable difference between ME/CFS and MS in our study is a history of recent infection prior to disease onset. Even recognising that our results are limited by the choice of factors we selected to investigate, our findings are consistent with the increasing body of evidence that has been published about the potential role of infections in the pathogenesis of ME/CFS, including common colds/flu.

scholarly journals The Australian Genetics of Depression Study: Study Description and Sample Characteristics

2019 ◽  
Author(s):  
Enda M Byrne ◽  
Katherine M Kirk ◽  
Sarah E Medland ◽  
John J McGrath ◽  
Richard Parker ◽  
...  
Keyword(s):  
Risk Factors ◽  
Short Form ◽  
Community Sample ◽  
Medical Practitioner ◽  
Diagnostic Interview ◽  
Clinical Depression ◽  
Online Questionnaire ◽  
Wide Range ◽  
History Of ◽  
Participant Group

AbstractObjectivesDepression is the most common psychiatric disorder and the largest contributor to global disability. The Australian Genetics of Depression study was established to recruit a large cohort of individuals who have been diagnosed with depression, and to investigate genetic and environmental risk factors for depression and response to commonly prescribed antidepressants. This paper describes the recruitment and characteristics of the sample.MethodsParticipants completed an online questionnaire that consisted of a compulsory module that assessed self-reported psychiatric history, clinical depression using the Composite Interview Diagnostic Interview Short Form, and experiences of using commonly prescribed antidepressants. Further voluntary modules assessed a wide range of traits of relevance to psychopathology. Participants who reported they were willing to provide a DNA sample were sent a saliva kit in the mail.ResultsA total of 20,689 participants, 75% of whom were female, enrolled in the study. The average age of participants was 43 years ± 15 years. 15,807 participants (76% of the participant group) returned saliva kits. The overwhelming majority of participants reported being given a diagnosis of depression by a medical practitioner and 88% met the criteria for a depressive episode. Rates of comorbidity with other psychiatric disorders were high. Two-thirds of the sample reported having taken more than one type of antidepressant during treatment for their depression.ConclusionsThis study was effective in recruiting a large community sample of people with a history of clinical depression, highlighting the willingness of Australians to engage with medical research. A combination of recruitment through health records and media as well as use of an online questionnaire made it feasible to recruit the large sample needed for investigating the genetics of common diseases. It will be a valuable resource for investigating risk factors for depression, treatment response to antidepressants and susceptibility to side effects.

scholarly journals Obstructive Pneumonia With Bronchial Foreign Body: A Case Report

2021 ◽  
Author(s):  
Hitomi Tanaka ◽  
Takatoshi Anno ◽  
Haruka Takenouchi ◽  
Hideaki Kaneto ◽  
Toru Oga ◽  
...  
Keyword(s):  
Foreign Body ◽  
Foreign Bodies ◽  
Laboratory Data ◽  
Vital Signs ◽  
Fish Bone ◽  
Case Presentation ◽  
Bronchial Foreign Body ◽  
Old Japanese ◽  
History Of ◽  
Normal Chest

Abstract Background: Bronchial foreign bodies are relatively uncommon in adults. There are a variety of symptoms induced by airway foreign bodies, although the typical symptoms of some bronchial foreign bodies are cough, wheezing, chest pain, hemoptysis and fever up. Case presentation: An 80-year-old Japanese man was referred to our hospital with symptom of 7-month history of cough and pneumonia. His chest radiograph showed a slight increase in opacity. His vital signs and his laboratory data were almost normal. Chest computed tomography revealed obstructive pneumonia and a bronchial foreign body. We performed bronchoscopy and detected a fish bone as an intrabronchial foreign body and finally removed it from the bronchi.Conclusions:It is very important to carefully perform medical consultation about the current and past medical history. People in some countries and regions such as Japan have a habit of eating fish. It is necessary to more carefully consider the possibility of some bronchial foreign body such as a fish bone, when we observe symptoms of persistent cough.

scholarly journals Prevalence of sexually transmitted infections and bacterial vaginosis among lesbian women: systematic review and recommendations to improve care

2019 ◽  
Vol 35 (3) ◽  
Author(s):  
Maira Libertad Soligo Takemoto ◽  
Mariane de Oliveira Menezes ◽  
Carla Betina Andreucci Polido ◽  
Débora de Souza Santos ◽  
Valeria Marli Leonello ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bacterial Vaginosis ◽  
Sexually Transmitted Infections ◽  
Lesbian Women ◽  
Care Providers ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Sexual Stigma ◽  
Wide Range ◽  
History Of

Our aim was to systematically review data about the risk of sexually transmitted infections (STI) and bacterial vaginosis among lesbian women and to suggest strategies to improve prevention, diagnosis and treatment. A search strategy for lesbian, STI and bacterial vaginosis was applied to PubMed, LILACS and BDENF databases. Of 387 unique references retrieved, 22 fulfilled the inclusion criteria (cross-sectional studies reporting prevalence for 8 STIs/bacterial vaginosis and history of a STI). The most frequent infection reported was bacterial vaginosis, and none study reported data on hepatitis B. A wide range of prevalence was observed for most infections. In terms of risk factors, the number of sexual partners, the past or current smoking, a history of forced sex and sexual stigma seem to increase the risk of STI and bacterial vaginosis. The findings of this review are discussed considering guidelines directly addressing the LGBT community’s health and relevant studies investigating both safe sexual practices and the intricate relationship between LGBT people and their care providers. A set of recommendations to improve preventive care for lesbian women is proposed. Affirming that little is known about the extent of STIs and bacterial vaginosis transmission in female-to-female sexual activities or about the risk factors for STI and bacterial vaginosis among lesbian women is reasonable. In fact, the overall quality of the studies was low or very low with significant uncertainty around their findings. However, we consider that the available knowledge indicates some paths to be followed by care providers and policy decision-makers to improve their actions towards better sexual health of lesbian women.

scholarly journals The Occurrence of Tongue Lesions among Dental Outpatients Attending Khanzad Dental Polyclinics Center in Erbil City

2020 ◽  
Vol 19 (2) ◽  
pp. 41-51
Author(s):  
Rawa hameed Mirkhan Abdulla ◽  
◽  
Ali Fakhree Alzubaidee
Keyword(s):  
Risk Factors ◽  
Allergic Reactions ◽  
Systemic Diseases ◽  
Pathological Conditions ◽  
Wide Range ◽  
History Of ◽  
Common Risk Factors ◽  
The Common ◽  
Age Range ◽  
Fissured Tongue

Background: The tongue can be targeted by a wide range of pathological conditions; the recognition of tongue lesions may be helpful in the early diagnosis of some systemic disorders. Objective: To determine the frequency and relation of the tongue conditions with risk factors among a group of dental outpatients attending a specialized dental polyclinics center in Erbil city, for individuals who are aware of their tongue lesion when to exist, and to estimate the possible coincidence between some of the tongue lesions with age, gender, smoking, alcohol drinking habit, allergic reactions, and systemic diseases. Patients and Methods: 1100 patients were examined for a period of 3 months from October 1st , 2019 – December 31st , 2019. Results: The frequency of tongue conditions was 52.8%, the study sample consists of 520 males 47.3%, and 580 females 52.7%. The age range was from 0.58 to 85 years, and 112 patients had one or more systemic diseases 92 of them were on regular medications. The most common frequent condition was fissured tongue diagnosed in 420 patients 38.2%. Conclusion: The common risk factors for tongue conditions in this study were old age, male gender, smoking, alcohol consumption, and medication intake, around one quarter (25.6%) of the sample has a family history of tongue condition. Keywords: Tongue conditions, fissured tongue, clinical study, coated tongue

scholarly journals Secondary infertility due to intrauterine retained fetal bone fragments

2014 ◽  
Vol 61 (3) ◽  
pp. 95-97
Author(s):  
Julian Habibaj ◽  
Halim Kosova ◽  
Valbona Bilali ◽  
Sokol Bilali
Keyword(s):  
Foreign Body ◽  
Histological Examination ◽  
Unusual Case ◽  
Uterine Cavity ◽  
Contraceptive Device ◽  
Secondary Infertility ◽  
Dead Bone ◽  
Intrauterine Contraceptive ◽  
History Of ◽  
Bone Fragments

We present an unusual case of a 28-year-old woman who had termination of pregnancy at 18 weeks of gestation. She visited our clinic with a history of secondary infertility for 3 years. A transvaginal ultrasonography revealed a hyperechogenic image that suggested presence of an intrauterine contraceptive device (IUCD). Hysteroscopy revealed a foreign body in the uterine cavity. The foreign body was removed with a hysteroscope using additional instruments that were not designed for hysteroscopy. Histological examination of the foreign body revealed fragments of dead bone.

scholarly journals Unusual case of nail in lung

2017 ◽  
Vol 4 (6) ◽  
pp. 1709
Author(s):  
Ashok P. Arbat ◽  
Sameer A. Arbat ◽  
Meenakshi S. Ghadge ◽  
Jayshree J. Upadhye
Keyword(s):  
Informed Consent ◽  
Foreign Body ◽  
Unusual Case ◽  
Age Groups ◽  
Foreign Body Aspiration ◽  
External Diameter ◽  
Lower Zone ◽  
X Ray ◽  
Tracheobronchial Foreign Body ◽  
History Of

Tracheobronchial foreign body aspiration is a health problem that can be seen in all age groups, and it requires urgent diagnosis and intervention. We report an unusual case of nail in lung. 45 years old male was referred to us with history of aspiration of nail 2 Days back and cough. X-ray Chest PA view showed radio-opaque foreign body in right lung-lower zone. Patient had undergone bronchoscopy 2 days ago with report stating, “Normal study; No foreign body Seen” Counselling of the patient and relatives was done. Informed consent was taken. Under general anaesthesia with intubation, fluoroscopy guided video bronchoscopy was performed with external diameter 5.6mm and working channel 2mm. Foreign body was localized and removed It’s an innovative technique with multi-disciplinary approach. Counselling of the patient and relatives is important. 

scholarly journals Migration of Ingested Fish Bone from Upper Aerodigestive Tract to the Skin of the Neck

2015 ◽  
Vol 23 (2) ◽  
pp. 81-83
Author(s):  
Mukulika Saha ◽  
Amit Chakrabarti ◽  
Amit Bikram Maity ◽  
Satadal Mandal
Keyword(s):  
Foreign Body ◽  
Foreign Bodies ◽  
Muscular Contraction ◽  
Fish Bone ◽  
Surrounding Tissue ◽  
Upper Aerodigestive Tract ◽  
Intact Skin ◽  
Hollow Viscus ◽  
Unusual Event ◽  
History Of

IntroductionIngested foreign bodies commonly get impacted in the upper aero digestive tract, but only a few of these foreign bodies have perforated the oesophagus and an even smaller number of these have migrated extraluminally. Case reportA 43 year old male patient presented with history of accidental ingestion of fish bone (F.B) 3 weeks back. On examination a sharp pointed swelling was seen over right side of neck and on palpation a pointed object was felt beneath the intact skin. Digital X-ray, ultrasonography of the neck and CT scan neck showed a linear obliquely placed foreign body on right side of neck at the level of thyroid gland. The foreign body was easily removed by an incision over the skin and was confirmed to be a fish bone. DiscussionHorizontally oriented foreign bodies are more likely to penetrate the lumen of a hollow viscus. The muscular contraction of the neck might account for this unusual event to some extent, one possible factor being that the presence of the foreign body in the soft tissue might have led to inflammation and oedema, which made the texture of the surrounding tissue loose and lax ; a sort of gel-sol interconversion. 

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