scholarly journals Transaortic Intra-Aortic Balloon Pump Catheter Insertion through a Separate Saphenous Vein Graft in Patients with Severe Aortoiliac Disease

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Faruk Toktas ◽  
Senol Yavuz ◽  
Cuneyt Eris ◽  
Suleyman Surer
Keyword(s):  
Coronary Artery ◽  
Saphenous Vein ◽  
Vein Graft ◽  
Saphenous Vein Graft ◽  
Multislice Ct ◽  
Ascending Aorta ◽  
Suitable Alternative ◽  
Aortoiliac Disease ◽  
Intra Aortic Balloon Pump ◽  
Iabp Support

Background. Intra-aortic balloon pump (IABP) is the most widely used mechanical assist device for hemodynamic support in high risk patients undergoing cardiac surgery. The aim of our study was to confirm whether transaortic route is a suitable alternative to allow IABP insertion in patients with severe aortoiliac diseases.Methods. This study included 7 consecutive patients undergoing coronary artery bypass grafting for severe coronary artery disease associated with severe aortoiliac disease. These patients could not be weaned from cardiopulmonary bypass and required the IABP support, which were placed through the ascending aorta. IABP catheter was inserted indirectly through a separate saphenous vein graft anastomosed to the ascending aorta by an end-to-side manner under a partial occluding clamp and advanced to the desired position in the descending thoracic aorta and exteriorly brought into the subcutaneous tissues in the jugulum.Results. The procedure was successfully performed in all the patients. The mean duration of IABP support was54.0±13.4hours. There were no in-hospital mortality and complications related to transaortic route. IABP removal did not require repeat sternotomy. At postoperative 6th month, multislice CT examination showed thrombotic occlusion at the remnant of the saphenous vein graft.Conclusions. This technique is a simple, reliable, and reproducible option in patients with severe aortoiliac disease in whom retrograde femoral route is not possible.

Reverse saphenous vein graft between ascending aorta and distal right coronary artery in man

1969 ◽  
Vol 23 (1) ◽  
pp. 119
Author(s):  
T.D. Hoeksema ◽  
D.R. Santschi ◽  
C.J. Frahm ◽  
J.H. Greenwald ◽  
A.V. Dumanian
Keyword(s):  
Coronary Artery ◽  
Right Coronary Artery ◽  
Saphenous Vein ◽  
Vein Graft ◽  
Saphenous Vein Graft ◽  
Ascending Aorta

scholarly journals Hemoptysis caused by saphenous vein graft aneurysm late after coronary artery bypass grafting

2005 ◽  
Vol 129 (6) ◽  
pp. 1432-1433 ◽  
Author(s):  
Yoshiharu Nishimura ◽  
Yoshitaka Okamura ◽  
Takeshi Hiramatsu ◽  
Hideaki Mori ◽  
Hiroki Hayashi ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Grafting ◽  
Coronary Artery Bypass ◽  
Saphenous Vein ◽  
Vein Graft ◽  
Saphenous Vein Graft ◽  
Artery Bypass ◽  
Bypass Grafting ◽  
Artery Bypass Grafting

Abstract 15922: Role of Polo-Like Kinase-1 in Intimal Hyperplasia in Saphenous Vein Graft: Potential Implication in Vein-Graft Disease

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Swastika Sur ◽  
Songcang Chen ◽  
Jeffrey T Sugimoto ◽  
Devendra K Agrawal
Keyword(s):  
Coronary Artery ◽  
Saphenous Vein ◽  
Intimal Hyperplasia ◽  
Vein Graft ◽  
Saphenous Vein Graft ◽  
Bypass Graft ◽  
Fold Increase ◽  
Potential Implication ◽  
Vein Graft Disease ◽  
Graft Disease

Coronary revascularization by coronary artery bypass grafting (CABG) is the choice of procedure in patients with multi-vessel or left main coronary artery disease. Concerns have been raised on the long term result of CABG using saphenous vein graft (SVG) as its patency significantly declines following surgery, compared to internal mammary artery (IMA), which is almost immune to restenosis. Proliferation of smooth muscle cells (SMCs) is the key event in the pathogenesis of intimal hyperplasia leading to SVG failure. PDGF-BB is a major growth factor released at the site of pulsatile stretch- and shear stress-induced graft injury. Here, we examined, for the first time, the expression of PLK1 and its phosphorylation/activation in isolated human bypass graft conduits. Human SV and IMA vessels were freshly collected, SMCs isolated and cultured up to 5th passage. In cultured SMCs, effect of PDGF-BB was examined on total and phosphorylated PLK1 (pPLK1) by Western blot analysis. Cell proliferation was measured using thymidine incorporation, MTT method and cell count. We found significantly higher expression of pPLK1 and total PLK1 in PDGF-stimulated SV SMCs than IMA. SV SMCs had 5-fold increase in the density of pPLK1 and had 2-fold increase in the density of total PLK1. While in the IMA SMCs, increase in pPLK1 was significantly lower than in SV SMCs. Also, this increase was not sustained. These data suggest a greater and sustained sensitivity of SV SMCs to PDGF-BB induced PLK1 activity than that of IMA. A PLK1 blocker inhibited PDGF-induced proliferation in both IMA and SV SMCs. These data demonstrate differential activity of PDGF-induced PLK1 activation, which was greater in SV SMCs than in IMA. This could explain the development of intimal hyperplasia in SV conduits than the IMA following CABG. Thus, inhibition of PLK1 could be a target in developing better therapeutic approach to prevent vein-graft disease.

The tumor was macroscopically resected, and the right coronary artery was bypassed using a saphenous vein graft

ASVIDE ◽  
2018 ◽  
Vol 5 ◽  
pp. 786-786
Author(s):  
Takamichi Inoue ◽  
Tadashi Kitamura ◽  
Shinzo Torii ◽  
Kagami Miyaji
Keyword(s):  
Coronary Artery ◽  
Right Coronary Artery ◽  
Saphenous Vein ◽  
Vein Graft ◽  
Saphenous Vein Graft ◽  
The Right
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