scholarly journals Macular Thickness Assessed with Optical Coherence Tomography in Young Chinese Myopic Patients

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Minghui Zhao ◽  
Qiang Wu ◽  
Ping Hu ◽  
Lili Jia
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Negative Correlation ◽  
Retinal Thickness ◽  
Macular Thickness ◽  
Optical Coherence ◽  
Foveal Thickness ◽  
Positive Correlation ◽  
Central Foveal Thickness ◽  
The Mean

Purpose.To evaluate the variations in macular thickness in young Chinese myopic persons and the association with axial length (AL), spherical equivalence refraction (SE), age, intraocular pressure, and sex.Methods.In total, 133 young Chinese myopic subjects between 18 and 30 years of age were selected. The macular thickness was assessed using third-generation optical coherence tomography. AL, intraocular pressure, and SE were also measured.Results.The mean central foveal thickness was191.1±15.3 µm. The macula was consistently thinner in women than in men. Central foveal thickness had a significant positive correlation with AL and a negative correlation with SE. In the inner and outer regions, the macular thickness had a positive correlation with SE and negative correlation with AL.Conclusions.The retina was thinner in women than in men. Associated with myopic progression and AL extension, the central foveal thickness increased, while the retinal thickness of the inner and outer regions decreased.

scholarly journals Changes in macular thickness after trabeculectomy with or without adjunctive 5-fluorouracil

2017 ◽  
Vol 24 (2) ◽  
pp. 93-100
Author(s):  
Aistė Kadziauskienė ◽  
Ernesta Strelkauskaitė ◽  
Eglė Mockevičiūtė ◽  
Rimvydas Ašoklis ◽  
Eugenijus Lesinskas ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Observational Study ◽  
Conflict Of Interest ◽  
Prospective Observational Study ◽  
Macular Thickness ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Postoperative Changes ◽  
The Mean

Conflict of interest. None of the authors have any conflict of interest to declare, financial or otherwise. No financial or other support was received for the study. Background. The  aim of the  study was to assess changes in macular thickness after trabeculectomy in respect to the  use of 5-fluorouracil (5-FU) as well as to analyse possible associations between the  postoperative changes in macular thickness and intraocular pressure (IOP). Materials and methods. The prospective observational study included 106 eyes (100 patients) with glaucoma who underwent trabeculectomy with or without 5-FU. Subsequently 5-FU needling was performed if failure of the  filtrating bleb occurred. Macular thickness and the  IOP were evaluated before, one week, and six months after the surgery. The mean and sectoral macular thickness was assessed using spectral domain optical coherence tomography. Results. The mean (±SD) IOP reduced from 27.71 (±6.88) mmHg at baseline to 18.3  (±8.1)  mmHg one week (p 

scholarly journals Macular thicknesses in patients with keratoconus: An optical coherence tomography study

2019 ◽  
Vol 78 (1) ◽  
Author(s):  
Sohani Deonarain ◽  
Azeezah Motala ◽  
Talent Mthembu ◽  
Nomfundo Nxele ◽  
Thabiso Phakathi ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Structural Changes ◽  
Corneal Transplantation ◽  
Preoperative Assessment ◽  
Study Groups ◽  
Optical Coherence ◽  
Foveal Thickness ◽  
Cross Sectional ◽  
Central Foveal Thickness ◽  
The Mean

Background: Keratoconus, a corneal ectasia associated with thickness and structural changes, has been reported to co-exist with posterior segment ocular conditions. However, very few studies have reported on macular thicknesses in individuals with keratoconus.Aim: The aim of this study was to investigate macular thicknesses in participants with keratoconus.Setting: This study was conducted at the University of KwaZulu-Natal (UKZN).Methods: A comparative cross-sectional research design was used. The sample consisted of 88 participants with 44 each in the control and keratoconus (15, 11 and 18 with mild, moderate and severe keratoconus, respectively) groups. Macular thicknesses were obtained with the Fourier-domain Optovue iVue100 optical coherence tomographer using the nine Early Treatment Diabetic Retinopathy Study sectors. Data were analysed using descriptive and inferential statistics.Results: Overall, the mean macular thicknesses were comparable among the control and three keratoconus groups (p ≥ 0.199). The mean central foveal thickness was greater in the severe keratoconus group (259 µm) than the other three study groups that showed similar measurements (247 µm – 248 µm). The central fovea was thinnest followed by the perifovea and parafovea in all four study groups. The mean thickness in the nasal and temporal quadrants of the parafovea and perifovea was thickest and thinnest, respectively, in all four study groups.Conclusion: Macular thicknesses via optical coherence tomography in individuals with keratoconus and controls are similar with thickness differences that are clinically insignificant. Consequently, macular thicknesses should be included in the preoperative assessment of individuals with keratoconus awaiting corneal transplantation to assess the integrity of the retina prior to surgery.

scholarly journals The Effect of Perioperative Topical Ketorolac 0.5% on Macular Thickness after Uneventful Phacoemulsification

2017 ◽  
Vol 2017 ◽  
pp. 1-8
Author(s):  
Derya Dal ◽  
Ozge Sarac ◽  
Yasin Toklu ◽  
Ayse Gul Kocak Altintas ◽  
Hasan Basri Cakmak ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Thickness ◽  
Topical Steroids ◽  
Optical Coherence ◽  
Foveal Thickness ◽  
The Mean ◽  
Group 2 ◽  
Group 1

Background. To evaluate the effects of topical 0.5% ketorolac treatment combined with topical steroids on macular thickness in cases who had uneventful phacoemulsification surgery. Methods. 58 eyes of 58 consecutive cases were included. The mean foveal thickness (MFT), parafoveal thickness (ParaFT), and perifoveal thickness (PeriFT) measurements were performed with optical coherence tomography (RTVue-100, Optovue, Fremont, CA, USA) preoperatively and at postoperative 1 week, 1 month, and 2 months. All cases received topical 0.1% dexamethasone postoperatively. Randomly selected cases additionally received topical 0.5% ketorolac, which started 2 days prior to surgery. Cases who received both topical steroids and ketorolac formed group 1 and subjects who received only topical steroids formed group 2. Results. The increase in mean MFT at the 1st week, 1st month, and 2nd months after surgery in group 1 was significantly lower than group 2 (P=0.008, P≤0.001, and P≤0.001, resp.). In group 1, the increase in mean ParaFT and PeriFT was significantly lower than group 2 at the 1st and 2nd months of the surgery (P<0.05 for all variables). Conclusions. Topical ketorolac combined with steroids is highly efficacious in order to prevent increment in thickness on each part of the macula even after an uneventful phacoemulsification surgery comparing to steroid monotheraphy.

scholarly journals The Association between Macular Thickness and Axial Length in Myopic Eyes

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Yeon Woong Chung ◽  
Moon Young Choi ◽  
Jung-sub Kim ◽  
Jin-woo Kwon
Keyword(s):  
Optical Coherence Tomography ◽  
Axial Length ◽  
High Myopia ◽  
Polynomial Regression ◽  
Macular Thickness ◽  
Optical Coherence ◽  
Regression Analyses ◽  
Foveal Thickness ◽  
P Values ◽  
The Relationship

Purpose. To investigate the relationship between macular thickness and axial length (AL) in myopic eyes. Methods. We included 441 myopic eyes in this study and measured macular thickness at the fovea and in other macular regions, using optical coherence tomography. We got thickness difference indices (TDIs) which by definition are the values of thickness difference obtained by subtracting the foveal thickness from that of each macula sector to evaluate macular contour. We then analyzed the relationships between AL and foveal thickness and AL and the TDIs of each macular sector. Results. In polynomial regression analyses, foveal thickness slope was relatively flat up to an AL of 25.5 mm and began to rise from 25.5–26.0 mm. The TDIs were also relatively flat up to AL of 25.5mm and started to show steepened negative slopes from around AL of 25.5 mm. When grouping myopia participants as high myopia or non-high myopia based on AL of 25.5mm, all macular indices of the high myopia group showed significant correlation with AL (all p values <0.01). But all indices of non-high myopia group had no significant correlation with AL. Conclusions. Average macular thickness profiles showed that appreciable changes started at an AL of 25.5mm.

Anterior chamber particles are associated with reduction of intraocular pressure after selective laser trabeculoplasty

2020 ◽  
pp. bjophthalmol-2019-315445
Author(s):  
Alexei N Kulikov ◽  
Dmitrii S Maltsev ◽  
Alina A Kazak ◽  
Maria A Burnasheva
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Open Angle Glaucoma ◽  
Anterior Segment ◽  
Optical Coherence ◽  
Selective Laser Trabeculoplasty ◽  
Cross Sectional ◽  
Laser Trabeculoplasty ◽  
The Mean

PurposeTo study the correlation between intraocular pressure (IOP) reduction and the number of hyper-reflective particles appearing in the anterior chamber following selective laser trabeculoplasty (SLT).Material and methodsIn this prospective interventional study, we included primary open-angle glaucoma patients. All participants received a standardised SLT session, which consisted of 100 pulses of 0.9 mJ over 360°. Anterior segment optical coherence tomography (4×4 mm volume scan, 101 horizontal cross-sectional scans) and applanation tonometry were performed before SLT and 15 min, 1 day, 1 week, 1 month and 3 months after. Particles were counted on cross-sectional scans using a standardised algorithm.ResultsIn this study, we included 25 patients (25 eyes), 14 males and 11 females, with a mean age of 68.9±10.5 and baseline IOP of 21.4±4.5 mm Hg. IOP at month 1 and month 3 after SLT was 18.0±4.0 and 17.4±3.3 mm Hg, respectively. The mean number of anterior chamber particles before and 15 min after SLT was 0.62±0.2 and 7.1±2.0 particles/mm2, respectively (p=0.036). There was a statistically significant correlation between the mean number of anterior chamber particles 15 min after SLT and IOP reduction at 1 month (r=0.62, p=0.03) and 3 months (r=0.71, p=0.01).ConclusionThe number of the anterior chamber particles graded using anterior segment optical coherence tomography after the procedure correlates with the IOP-lowering effect of SLT.

Association of Spectral-Domain Optical Coherence Tomography Findings with Visual Outcome of Macula-Off Rhegmatogenous Retinal Detachment Surgery

2015 ◽  
Vol 234 (2) ◽  
pp. 83-90 ◽  
Author(s):  
Hae Min Kang ◽  
Sung Chul Lee ◽  
Christopher Seungkyu Lee
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Detachment ◽  
Rhegmatogenous Retinal Detachment ◽  
Subretinal Fluid ◽  
Visual Outcome ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Foveal Thickness ◽  
Central Foveal Thickness ◽  
Sd Oct

Purpose: To identify prognostic factors for the visual outcome for patients with macula-off rhegmatogenous retinal detachment (RRD). Methods: The medical records of 27 patients (27 eyes) with macula-off RRD were retrospectively investigated. In addition to clinical characteristics, spectral-domain optical coherence tomography (SD OCT) images were analyzed. Results: The central foveal thickness at baseline was 923 ± 499.5 µm, and the mean height of the subretinal fluid was 697.8 ± 463.6 µm. Dropout of backreflection at the fovea was detected on preoperative SD OCT in 8 patients (29.6%). The external limiting membrane was disrupted in 5 patients (18.5%) as was the photoreceptor integrity in 9 patients (33.3%) at 12 months. On multiple regression analysis, backreflection integrity was the only predictive factor for postoperative visual outcome (B = 0.179, p = 0.020). Conclusions: Backreflection integrity on preoperative SD OCT seems to be helpful in predicting the postoperative visual outcome in macula-off RRD patients.

scholarly journals Central Macular Thickness in Children with Myopia, Emmetropia, and Hyperopia: An Optical Coherence Tomography Study

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Gordon S. K. Yau ◽  
Jacky W. Y. Lee ◽  
Tiffany T. Y. Woo ◽  
Raymond L. M. Wong ◽  
Ian Y. H. Wong
Keyword(s):  
Optical Coherence Tomography ◽  
Axial Length ◽  
Retinal Nerve Fibre Layer ◽  
Macular Thickness ◽  
Chinese Children ◽  
Central Macular Thickness ◽  
Optical Coherence ◽  
The Mean ◽  
Nerve Fibre Layer ◽  
Chinese Subjects

Purpose.To investigate the central macular thickness (CMT) in myopic, emmetropic, and hyperopic Chinese children using Optical Coherence Tomography.Methods.168 right eyes of Chinese subjects aged 4–18 were divided into 3 groups based on their postcycloplegic spherical equivalent: myopes (<−1.0 D); emmetropes (≥−1.0 to ≤+1.0 D); and hyperopes (>+1.0 D) and the CMT was compared before/after age adjustment. The CMT was correlated with age, axial length, and peripapillary retinal nerve fibre layer (RNFL).Results.The mean CMT was274.9±50.3 μm and the mean population age was7.6±3.3years. The CMT was thickest in the myopes (283.3±57.3 μm,n=56), followed by the hyperopes (266.2±55.31 μm,n=60) and then emmetropes (259.8±28.7 μm,n=52) (allP<0.0001). When adjusted for age, myopes had a thicker CMT than the other 2 groups (allP<0.0001) but there was no CMT difference between the emmetropes and hyperopes (P>0.05). There was no significant correlation between CMT with age, axial length, or peripapillary RNFL (allP≥0.2).Conclusion.Chinese children with myopia had a thicker CMT than those with emmetropia or hyperopia. There was no correlation of the CMT with age, axial length, or peripapillary RNFL thickness.

COMPARISON OF FOVEAL THICKNESS MEASURED WITH THE RETINAL THICKNESS ANALYZER AND OPTICAL COHERENCE TOMOGRAPHY

Retina ◽  
2001 ◽  
Vol 21 (6) ◽  
pp. 596-601 ◽  
Author(s):  
ALJOSCHA S. NEUBAUER ◽  
SIEGFRIED PRIGLINGER ◽  
STEFANIE ULLRICH ◽  
MARTIN BECHMANN ◽  
MARTIN J. THIEL ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Thickness ◽  
Optical Coherence ◽  
Foveal Thickness ◽  
Retinal Thickness Analyzer

scholarly journals Result of intravitreal aflibercept injection for myopic choroidal neovascularization

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Shih-Lin Chen ◽  
Pei-Ling Tang ◽  
Tsung-Tien Wu
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Choroidal Neovascularization ◽  
Optical Coherence ◽  
Foveal Thickness ◽  
Flow Area ◽  
Myopic Choroidal Neovascularization ◽  
Central Foveal Thickness ◽  
Intravitreal Aflibercept ◽  
Myopic Cnv

Abstract Background The current study aimed to evaluate the efficacy of intravitreal aflibercept injections as the primary treatment for subfoveal/juxtafoveal myopic choroidal neovascularization (CNV) by using optical coherence tomography (OCT). Optical coherence tomography angiography (OCTA) was further used for some patients to detect the changes of CNV after treatment. Methods In the present study, 21 treatment-naive eyes of 21 patients with subfoveal/juxtafoveal myopic CNV received primary intravitreal aflibercept injections and were under follow-up for a minimum duration of 12 months. Among the 21 patients, 12 underwent OCTA to evaluate the changes in central foveal thickness, selected CNV area, and flow area. Results The mean best-corrected visual acuity (BCVA) pertaining to all the patients significantly improved from the baseline value of 0.7 to 0.3 logMAR after treatment for 12 months (P = 0.001). However, the improvements in the median BCVA after treatment for three and 12 months were not statistically significant in the younger group (< 50 years), compared to the older group (≥ 50 years). One aflibercept injection resolved the CNV in 47.6% (10/21) of the patients. The younger group displayed greater improvement in the median central foveal thickness, compared to the older group. OCTA revealed interlacing or disorganized pattern at the level of the outer retinal layer in 12 subjects with myopic CNV. After 3 months of treatment, both groups displayed a decrease in the size of the selected CNV area and flow area. The interlacing group displayed a trend towards better anatomical improvements. Conclusion Intravitreal aflibercept injection provides long-term improvement in visual acuity in patients with myopic CNV. Eyes with the interlacing pattern on OCTA displayed a greater decrease in size and flow after aflibercept injection. Trial registration Before data collection, written informed consent was obtained from each participant, whose identity information was protected by encryption and conversion to a non-identifiable format and removing data links. This study was approved by the Institutional Review Board of Kaohsiung Veterans General Hospital (KSVGH21-CT1–17).

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