scholarly journals Physical Activity and Quality of Life in Retinitis Pigmentosa

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Joshua D. Levinson ◽  
Ethan Joseph ◽  
Laura A. Ward ◽  
Joe R. Nocera ◽  
Machelle T. Pardue ◽  
...  

Purpose. Aerobic exercise has been found to be neuroprotective in animal models of retinal degeneration. This study aims to report physical activity levels in patients with RP and investigate the relationship between physical activity and vision-related quality-of-life (QOL). Materials and Methods. A retrospective study of adult patients with RP examined in 2005–2014. Physical activity levels were assessed using the Godin Exercise Questionnaire. The NEI-Visual Function Questionaire-25 (VFQ-25), SF-36 General Health survey, and Pepper Assessment Tool for Disability (PAT-D) were administered. Results. 143 patients participated. 81 (56.6%) patients were classified as “active” and 62 (43.4%) as “insufficiently active” by Godin score. VFQ-25 revealed statistically significant differences between the active and insufficiently active patients, including overall visual function (53.3 versus 45.1, p=0.010), color vision (73.8 versus 52.9, p<0.001), and peripheral vision (34.3 versus 23.8, p=0.021). The physical component of the SF-36 and the PAT-D survey also demonstrated statistically significant differences (47.2 versus 52.9, p=0.002; 24.3 versus 30.0, p=0.010). Active patients had a higher initial Goldmann visual field (GVF) score (74.8 versus 60.1 degrees, p=0.255) and final GVF score (78.7 versus 47.1 degrees, p=0.069) but did not reach statistical significance. Conclusions. In RP, increased physical activity is associated with greater self-reported visual function and QOL.

2020 ◽  
Vol 30 (11) ◽  
pp. 1784-1790
Author(s):  
Steven Fleming ◽  
Tamara Jones ◽  
Monika Janda ◽  
Dimitrios Vagenas ◽  
Leigh Ward ◽  
...  

BackgroundParticipating in physical activity after a diagnosis of cancer is associated with reduced morbidity and improved outcomes. However, declines in, and low levels of, physical activity are well documented in the broader cancer population, but with limited evidence following gynecological cancer.ObjectiveTo describe physical activity levels from before and up to 2 years after gynecological cancer surgery; to explore the relationship between physical activity patterns and quality of life; and to describe characteristics associated with physical activity trajectories post-gynecological cancer.MethodsWomen with gynecological cancer (n=408) participated in a prospective study that assessed physical activity and quality of life pre-surgery (baseline), at 6 weeks, and 3, 6, 9, 12, 15, 18 and 24 months post-surgery. Validated questionnaires were used to assess physical activity (Active Australia Survey) and quality of life outcomes (Functional Assessment of Cancer Therapy-General). Generalized estimating equation modeling, group-based trajectory analysis, and analysis of variance were used to identify physical activity levels over time, to categorize women into physical activity trajectory groups, and to assess the relationship between physical activity levels and quality of life, respectively.ResultsWomen had a mean±SD age of 60±11.4 years at diagnosis, with the majority diagnosed with endometrial cancer (n=235, 58%) or stage I disease (n=241, 59%). Most women (80%) started with and maintained low levels of physical activity (1–10 metabolic equivalent task hours per week), reported no physical activity throughout the follow-up period, or reduced physical activity levels over time. Only 19% of women maintained or doubled physical activity levels, so that by 24 months post-diagnosis they were engaging in sufficient levels of physical activity. Women with endometrial cancer (58% of the sample) were more likely to be overweight or obese and to report low levels of physical activity or none at all. Higher physical activity levels were associated with higher quality of life (p<0.05).ConclusionThe low baseline and surveillance levels of physical activity show that the vast majority of gynecological cancer survivors have the ability to improve their physical activity levels. Integration of physical activity advice and support into standard care could lead to gains in quality of life during gynecological cancer survivorship.


Lupus ◽  
2016 ◽  
Vol 26 (7) ◽  
pp. 690-697 ◽  
Author(s):  
T Dassouki ◽  
F B Benatti ◽  
A J Pinto ◽  
H Roschel ◽  
F R Lima ◽  
...  

Objective The objectives of this paper are to objectively measure habitual physical activity levels in patients with primary Sjögren’s syndrome (pSS) with mild disease activity and to determine to which extent it may be associated with physical capacity and function and clinical features. Methods In this cross-sectional study, 29 women with pSS were objectively assessed for habitual physical activity levels (using accelerometry) and compared with 20 healthy women (CTRL) frequency-matched for physical activity levels, age, body mass index, and body fat percentage with regard to physical capacity and function, fatigue, depression, pain, and health-related quality of life. Results pSS showed 8.5 min/day of moderate-to-vigorous physical activity (MVPA) when only MVPA accumulated in bouts ≥ 10 min was considered; when considering total MVPA (including bouts < 10 min), average levels were 26.3 min/day, with 62% of pSS patients achieving the recommendation (≥ 21.4 min/day). Moreover, pSS showed lower VO2peak, lower muscle strength and function, higher fatigue, and poorer health-related quality of life when compared with CTRL ( p < 0.05). These differences (except for aerobic capacity) were sustained even when only individuals achieving the minimum of 21.4 min/day of total MVPA in both groups were compared. Finally, MVPA time was significantly correlated with aerobic conditioning, whereas total counts and sedentary time were associated with lower-body muscle strength and the bodily-pain domain of SF-36 in patients with pSS. Conclusion When compared to physical activity-matched healthy controls, pSS patients showed reduced physical capacity and function, increased fatigue and pain, and reduced health-related quality of life. Except for aerobic conditioning, these differences were sustained when only more physically active participants were compared, indicating that minimum recommended levels of physical activity for the general population may not be sufficient to counteract pSS comorbidities.


2019 ◽  
Vol 12 (4) ◽  
pp. 110
Author(s):  
Süleyman Gönülateş ◽  
Mehmet Ali Ozturk

The aim of this study is to investigate whether there is a positive or negative relationship between the quality of life of the students and their physical activity levels (PAL). A total of 469 students participated in the study (female = 209, male = 260). The physical activity levels of the participants were determined as "International Physical Activity Questionnaire Short Form (IPAQ-SF)" and their quality of life was determined by the World Health Organization (WHOQOL-BREF). In the statistical analysis, parametric tests were used because of the normal and homogeneous distribution of the data. The difference between PAL and quality of life scores was evaluated by MANOVA test. The relationship between PAL and quality of life of the participants was tested by Pearson Correlation test. The overall health status of the participants was 87% (n = 408) good-very good and the level of physical activity was 88.1% (n = 413) moderate-high active. There was no statistically significant difference between the PAL and quality of life scores of the participants. After Pearson Correlation test, there was no correlation between PAL and quality of life at r2 at p


2015 ◽  
Vol 7 (1) ◽  
pp. 29-41
Author(s):  
ADEEL NAZIR AHMAD ◽  
KIMBERLEY L. EDWARDS

Background: People with asthma believe their condition prevents them from undertaking physical activity. The objective was to determine the association between habitual physical activity levels and the quality of life in adults with asthma and meeting the physical activity guidelines. Material/Methods: A cross-sectional survey of adults (aged >18) with asthma was conducted in three general practices in Nottingham, UK (n = 128). A self-reported short form International Physical Activity Questionnaire, mini Asthma Quality of Life Questionnaire and a demographic questionnaire (age, gender, ethnicity and BMI) were used to collect data. Physical activity was provided in minutes for different activities to enable the habitual weekly MET-minutes to be calculated, and the quality of life score was determined. Results: Among 128 respondents, 22% met the physical activity guidelines. Mostly younger, white, male, normal weight participants had higher physical activity levels and better asthma quality of life. Mean total asthma quality of life score was 4.5. Linear regression modelling showed a positive association between the total physical activity and the quality of life score (p < 0.001); thus higher physical activity levels were associated with less/no asthma quality of life impairment (higher score). Conclusions: The majority of asthmatics in this study had low physical activity levels, did not meet the recommended physical activity guidelines and had impaired quality of life. A strong positive association between physical activity and asthma quality of life supports the view that adults with asthma should be encouraged to be sufficiently physically active, which could be associated with a better asthma related quality of life.


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