scholarly journals Schwannoma of the Appendix Orifice

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Maha Alkhattab ◽  
Amenah Dhannoon ◽  
Rishabh Sehgal ◽  
Conor Gormley ◽  
Margaret Sheehan ◽  
...  
Keyword(s):  
Right Hemicolectomy ◽  
Anatomical Location ◽  
Mesenchymal Tumors ◽  
Benign Schwannoma ◽  
Standard Management ◽  
Routine Surveillance ◽  
Complete Surgical Resection ◽  
Spindle Cell Proliferation ◽  
History Of ◽  
Benign Nature

Schwannomas are rare mesenchymal tumors. They are usually diagnosed incidentally during endoscopic or diagnostic imaging for another reason. Malignant transformation is rare. In this case report, we present an incidental schwannoma protruding through the appendiceal orifice diagnosed during endoscopy. A healthy 56-year-old female underwent a surveillance colonoscopy for family history of colorectal cancer. A prominent and edematous appendiceal orifice was noted, and the area was aggressively biopsied. Histopathological assessment revealed a benign schwannoma. Computerized topography was unremarkable. Subsequently, the patient underwent a right hemicolectomy. Patient is scheduled to undergo routine surveillance in three years. Grossly, schwannomas are white, encapsulated, and well-circumscribed lesions that stain strongly positive for S100, GFAP, and CD57. Histologically, schwannomas demonstrate spindle cell proliferation. Several imaging modalities have been utilized in the diagnosis and management of mesenchymal neoplasms. Despite the benign nature of the diagnosis, complete surgical resection with clear margins remains the gold standard management strategy. Our case highlights the presence of a relatively uncommon tumor in an unusual anatomical location.

scholarly journals Primary Intracranial Leiomyosarcoma: Report of a Case and Review of the Literature

Sarcoma ◽  
2006 ◽  
Vol 2006 ◽  
pp. 1-3 ◽  
Author(s):  
Sakeer Hussain ◽  
Anil Nanda ◽  
Marjorie Fowler ◽  
Federico L. Ampil ◽  
Gary V. Burton
Keyword(s):  
Ct Scan ◽  
Review Of The Literature ◽  
Therapeutic Approaches ◽  
Provisional Diagnosis ◽  
Mesenchymal Tumors ◽  
Bony Destruction ◽  
Complete Surgical Resection ◽  
History Of ◽  
Histopathologic Analysis ◽  
Pet Scans

A 26-year old man presented with a 3-month history of a progressively enlarging palpable parieto-occipital mass. A CT scan indicated the lesion arose from the dura with bony destruction. A stealth assisted craniotomy was performed with the provisional diagnosis of osteoblastic meningioma. Further histopathologic analysis of the intracranial mass was consistent with leiomyosarcoma. Staging evaluation, including CT and PET scans, demonstrated no other sites of disease. Despite complete surgical resection and radiotherapy to the resection site, the disease recurred locally and systematically 5 months later. Primary intracranial mesenchymal tumors are rare and few cases have been previously reported. Outcomes have been universally poor and current therapeutic approaches appear to have only limited benefit.

scholarly journals Undifferentiated pleomorphic sarcoma in oropharyngeal mucosa of patients with multiple basal cell carcinomas

Rare Tumors ◽  
2021 ◽  
Vol 13 ◽  
pp. 203636132110264
Author(s):  
Andrea Dekanić ◽  
Marko Velepič ◽  
Margita Belušić Gobić ◽  
Ita Hadžisejdić ◽  
Nives Jonjić
Keyword(s):  
Differential Diagnosis ◽  
Basal Cell ◽  
Polypoid Lesion ◽  
Older Patient ◽  
Mesenchymal Tumors ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Pleomorphic Sarcoma ◽  
Basal Cell Carcinomas ◽  
History Of ◽  
Multiple Basal Cell Carcinomas

Malignant mesenchymal tumors of oropharyngeal mucosa are rare. Those with fibroblastic and histiocytic differentiation in the skin are called atypical fibroxanthoma (AFX) and in the soft tissue undifferentiated pleomorphic sarcoma (UPS). Here we present a case of an older patient with a history of multiple basal cell carcinomas and recently with a rapidly growing polypoid lesion in the mucosa of posterior oropharyngeal wall with AFX/UPS morphology. The differential diagnosis, histological pitfalls of this poorly characterized mesenchymal lesions, and the challenges associated with treatment are discussed.

Three Cases of Pyogenic Granuloma of the Gastrointestinal Tract

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S119-S119
Author(s):  
Yukihiro Nakanishi ◽  
Preeti Behl ◽  
Byron Crawford
Keyword(s):  
Gastrointestinal Tract ◽  
Pyogenic Granuloma ◽  
Right Hemicolectomy ◽  
Capillary Hemangioma ◽  
Deficiency Anemia ◽  
Significant Drop ◽  
Massive Gastrointestinal Bleeding ◽  
History Of ◽  
Mixed Inflammatory Infiltrate ◽  
Pedunculated Polyp

Abstract Pyogenic granuloma also known as lobular capillary hemangioma occurs commonly in the skin and oral mucosa. This entity has been rarely reported in the gastrointestinal tract. We herein report three cases of pyogenic granuloma, located in the duodenum, ileum, and rectum, respectively. Case 1 is a 54-year-old female with a history of angioimmunoblastic T-cell lymphoma who underwent an esophagogastroduodenoscopy for severe heartburn. The endoscopy showed a 13-mm nonbleeding, pedunculated polyp in the second portion of duodenum, which was removed using a hot snare after injection of epinephrine. The patient had an episode of massive gastrointestinal bleeding postpolypectomy, with a significant drop of her hemoglobin, which was managed with blood transfusion. Case 2 is a 68-year-old male with a history of right hemicolectomy due to trauma who had a colonoscopy for chronic diarrhea. The colonoscopy revealed a 14-mm, nonbleeding, pedunculated polyp in the ileum, located 3 cm from the ileocolonic anastomosis. The polyp was removed with hot snare, without complications. Case 3 is a 44-year-old female with morbid obesity who underwent a colonoscopy for iron-deficiency anemia. The colonoscopy showed an 8-mm multilobulated sessile lesion in the distal rectum, which was completely removed using hot snare. No complications were seen postpolypectomy. Histological examination of all the three polyps showed a proliferation of capillary-sized blood vessels with a mixed inflammatory infiltrate, resembling granulation tissue. Additionally, the ileal polyp in our case had marked eosinophilic infiltrate, the etiology of which remains unknown. In conclusion, pyogenic granuloma, given its vascular nature, can be a cause of bleeding in the gastrointestinal tract. Awareness regarding this rare entity is important for its proper diagnosis and treatment.

scholarly journals A Case of Benign Schwannoma of the Ascending Colon Treated With Laparoscopic-Assisted Wedge Resection

2013 ◽  
Vol 98 (4) ◽  
pp. 315-318 ◽  
Author(s):  
Se-Jin Baek ◽  
Won Hwangbo ◽  
Jin Kim ◽  
In-Sun Kim
Keyword(s):  
Submucosal Tumor ◽  
Wedge Resection ◽  
Ascending Colon ◽  
Mesenchymal Tumors ◽  
Benign Schwannoma ◽  
S 100 ◽  
Colon And Rectum ◽  
Laparoscopic Assisted ◽  
Specific Symptoms ◽  
Diffuse Positivity

Abstract Isolated colonic schwannomas are rare gastrointestinal mesenchymal tumors. Only a small number of cases have been reported. Occurrence of these tumors is more common in the stomach than in the large intestine. These spindle cell lesions are distinct from leiomyoma, leiomyosarcoma, and gastrointestinal stromal tumors because the tumor cells have a distinct immunophenotype, with strong diffuse positivity for S-100 and vimentin, as well as corroborative negative staining of CD117 and smooth muscle markers. We present a case of colonic schwannoma in a 70-year-old woman who had no specific symptoms. The patient was diagnosed with a submucosal tumor in the ascending colon on colonoscopy and abdominal computed tomography. Laparoscopic-assisted wedge resection of colon was performed. The very rare pathologic diagnosis of ascending schwannoma was made postoperatively. This case is interesting because schwannomas of the colon and rectum are extremely rare and are treated by laparoscopic-assisted wedge resection.

scholarly journals Carcinoembryonic Antigen Elevation in a Patient with SARS-CoV-2 and a History of Colon Cancer

2021 ◽  
pp. 802-805
Author(s):  
Taha Alrifai ◽  
Anita Sharko ◽  
William T. Leslie
Keyword(s):  
Health Care ◽  
Colon Cancer ◽  
Severe Acute Respiratory Syndrome ◽  
Carcinoembryonic Antigen ◽  
Health Care Delivery ◽  
Care Delivery ◽  
Prognostic Biomarkers ◽  
Diagnosis And Treatment ◽  
Routine Surveillance ◽  
History Of

The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic continues to affect millions of people and impact health-care delivery worldwide. New data and insights into the diagnosis and treatment of SARS-CoV-2 are emerging rapidly. Several prognostic biomarkers have been studied in patients with SARS-CoV-2. Among those biomarkers is the carcinoembryonic antigen (CEA). We report the case of a 46-year-old male with a history of colon cancer who was found to have an elevated CEA level during routine surveillance. Further workup confirmed a diagnosis of SARS-CoV-2 infection. The CEA level normalized with the resolution of the infection.

TOOTH-RASHES AS DESCRIBED BY MICHAEL UNDERWOOD (1737-1820), THE FOUNDER OF MODERN PEDIATRICS

PEDIATRICS ◽  
1969 ◽  
Vol 43 (3) ◽  
pp. 459-459
Author(s):  
T. E. C.
Keyword(s):  
Scarlet Fever ◽  
Erythema Nodosum ◽  
Whole Body ◽  
Deciduous Teeth ◽  
History Of ◽  
History Of Pediatrics ◽  
Benign Nature ◽  
Almost All ◽  
As If

I know of no contemporary pediatrician who believes that the cutting of deciduous teeth causes skin rashes. But, almost all the great figures in the history of pediatrics believed firmly that teething was associated with a riety of rashes. Michael Underwood, who more than anyone else laid the foundation of modern pediatrics, wrote about tooth-rashes as follows: A very common rash, appears chiefly in teething children, which yery much resembles the measles, and has been sometimes mistaken for it. It is preceded by sickness at the stomach, but is attended by very little fever; though the rash continues very florid for three days, like the measles, but does not dry off in the manner of that disease. . . . While the double or eye-teeth are cutting, I have noticed a rash Which at its first appearance is very similar to the above, and has likewise been mistaken for the measles. It, however, soon spreads into larger spots and patches of bright red, and afterwards of a darker hue, resembling the ill-looking petechiae which appear in bad fevers, but is, nevertheless, of a benign nature. It is, indeed, attended with some fever, arising possibly from the irritation occasioned by teething, and has been followed by small and hard round tumours on the legs, which softening in two or three days, always appear as if they would suppurate, though I believe they never do . . . [? erythema nodosum, T. E. C., Jr.] I have seen a third kind of rash, in appearance resembling the measles, and, like it, covering the whole body, but with larger intermediate patches, like the eruption in the scarlet fever. . . .

Natural history of ampullary adenoma in familial adenomatous polyposis: reconfirmation of benign nature during extended surveillance

2000 ◽  
Vol 95 (6) ◽  
pp. 1557-1562 ◽  
Author(s):  
Takayuki Matsumoto ◽  
Mitsuo Iida ◽  
Shotaro Nakamura ◽  
Kazuoki Hizawa ◽  
Takashi Yao ◽  
...  
Keyword(s):  
Familial Adenomatous Polyposis ◽  
Natural History ◽  
Adenomatous Polyposis ◽  
Ampullary Adenoma ◽  
History Of ◽  
Benign Nature

scholarly journals Subsequent Development of Desmoid Tumor after a Resected Gastrointestinal Stromal Tumor

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Areen Abdulelah Murshid ◽  
Hatim Q. Al-Maghraby
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Desmoid Tumor ◽  
Case Reports ◽  
Previous History ◽  
Subsequent Development ◽  
Stromal Tumor ◽  
Desmoid Tumors ◽  
Mesenchymal Tumors ◽  
First Case ◽  
History Of

Desmoid tumors (deep fibromatosis) of the mesentery are rare mesenchymal tumors. They are often misdiagnosed, especially with a previous history of resection for gastrointestinal stromal tumor (GIST). Immunohistochemistry can help differentiate between these two tumors. In this article, we present a case we had encountered: a Desmoid tumor developing in a patient with a history of GIST 3 years ago. It is the first case of GIST with subsequent development of Desmoid tumor to be reported in Saudi Arabia. We discuss the two entities of Desmoid tumor and GIST by comparing their definitions, clinical presentations, histological features, immunohistochemistry stains, molecular pathogenesis, prognosis, and treatment. We also discuss the relationship between GIST and the subsequent development of Desmoid tumors and compare our case with case reports in literature.

scholarly journals Pleomorphic adenoma of dorsum of the nose: a rare occurrence

2020 ◽  
Vol 6 (10) ◽  
pp. 1919
Author(s):  
Rajiv Kumar Jain ◽  
Chultim D. Bhutia ◽  
Deepak Kumar Gupta ◽  
Ashvanee Kumar Chaudhary ◽  
Gagan Rangari ◽  
...  
Keyword(s):  
Pleomorphic Adenoma ◽  
Surgical Excision ◽  
Histological Evaluation ◽  
Prior History ◽  
Salivary Gland Tumours ◽  
Complete Surgical Excision ◽  
Complete Surgical Resection ◽  
Long Term Follow Up ◽  
History Of ◽  
Benign Salivary Gland Tumours

<p class="abstract">Pleomorphic adenoma are common benign salivary gland tumours, which are found in majority in major salivary glands such as parotids and submandibular glands. However, Pleomorphic adenoma to originate from dorsum of the nose is a rare entity. In rare cases, it can be found in unusual sites such as upper aero digestive tracts, palate and lacrimal glands. Complete surgical resection is the treatment of choice. Though, the evolution to malignancy and recurrence is not usually encountered, still a long-term follow-up is recommended. Here, we report a 53 year old female , complained of swelling in the left side of dorsum of nose for 10 years with a feeling of heaviness over the left side of face and difficulty in vision on the side of swelling due to the enlarged size of the swelling which gave a feeling of vision disruption , also had a prior history of  incision and drainage 4 years ,done elsewhere. On clinical examination, nodular mass was palpated on left side dorsum of nose which was freely mobile, and Skin over the swelling had blackish pigmentation. Anterior rhinoscopy revealed no abnormalities. Complete surgical excision via a lateral rhinotomy incision was performed. Cytological and histological evaluation revealed the presence of pleomorphic adenoma. We observed a decent cosmetic outcome with no evidence of recurrence.</p>

Solitary neurofibroma of the larynx: a diagnostic challenge

2021 ◽  
Vol 14 (1) ◽  
pp. e236682
Author(s):  
Bruno Cunha ◽  
Ricardo Pacheco ◽  
Isabel Fonseca ◽  
Alexandra Borges
Keyword(s):  
Differential Diagnosis ◽  
Tumour Size ◽  
Negative Consequences ◽  
Diagnostic Challenge ◽  
Presenting Symptoms ◽  
Aged Woman ◽  
Complete Surgical Resection ◽  
Long Term Follow Up ◽  
Middle Aged Woman ◽  
Benign Nature

Solitary neurofibromas of the larynx are extremely rare, with a total of 15 cases described in the literature. Nonetheless, acquaintance with this diagnosis is important, as misdiagnoses can have negative consequences. Presenting symptoms are non-specific and depend on tumour size and location. As well-defined submucosal masses with a broad differential diagnosis, they remain a clinical and radiological challenge. While some characteristics might favour a benign nature and subtle signs might help narrow the differential diagnosis, imaging alone is not sufficient for differentiation and definitive diagnosis requires a biopsy. Complete surgical resection and long-term follow-up is indicated. We share our experience on a case of a solitary laryngeal neurofibroma in a middle-aged woman, presenting with a large well-defined paraglottic lesion.

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